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Machine learning (ML) is playing an increasingly important role in scientific research. In conjunction with classical statistical approaches, ML-assisted analytical strategies have shown great promise in accelerating research findings. This…

Machine Learning · Statistics 2024-11-01 Jiacheng Miao , Qiongshi Lu

From structural biology to epidemiology, predictions from machine learning (ML) models increasingly complement costly gold-standard data, enabling faster, more affordable, and scalable scientific inquiry. In response, prediction-based (PB)…

Machine Learning · Statistics 2026-01-21 Jessica Gronsbell , Jianhui Gao , Zachary R. McCaw , Yaqi Shi , David Cheng

Artificial intelligence (AI) and machine learning (ML) are increasingly used to generate data for downstream analyses, yet naively treating these predictions as true observations can lead to biased results and incorrect inference. Wang et…

Prediction-Powered Inference (PPI) is a powerful framework for enhancing statistical estimates by combining limited gold-standard data with machine learning (ML) predictions. While prior work has demonstrated PPI's benefits for individual…

Machine Learning · Statistics 2025-11-10 Sida Li , Nikolaos Ignatiadis

Semi-supervised learning (SSL) arises in practice when labeled data are scarce or expensive to obtain, while large quantities of unlabeled data are readily available. With the growing adoption of machine learning techniques, it has become…

Machine Learning · Statistics 2026-05-29 Jiawei Shan , Zhifeng Chen , Yiming Dong , Yazhen Wang , Jiwei Zhao

As artificial intelligence and machine learning tools become more accessible, and scientists face new obstacles to data collection (e.g., rising costs, declining survey response rates), researchers increasingly use predictions from…

Machine Learning · Statistics 2025-12-08 Stephen Salerno , Kentaro Hoffman , Awan Afiaz , Anna Neufeld , Tyler H. McCormick , Jeffrey T. Leek

This paper introduces a new framework for data efficient and versatile learning. Specifically: 1) We develop ML-PIP, a general framework for Meta-Learning approximate Probabilistic Inference for Prediction. ML-PIP extends existing…

Machine Learning · Statistics 2020-07-14 Jonathan Gordon , John Bronskill , Matthias Bauer , Sebastian Nowozin , Richard E. Turner

In modern data analysis, it is common to use machine learning methods to predict outcomes on unlabeled datasets and then use these pseudo-outcomes in subsequent statistical inference. Inference in this setting is often called…

Methodology · Statistics 2024-11-04 Feng Gan , Wanfeng Liang , Changliang Zou

Unlabeled data are increasingly prevalent in contemporary economic studies, yet their effective use for improving prediction remains challenging because the outcomes are often costly or even infeasible to observe. Machine learning methods…

Methodology · Statistics 2026-05-12 Fuzhi Xu , Xingyu Yan , Xinyu Zhang

Incorporating auxiliary information alongside primary data can significantly enhance the accuracy of simultaneous inference. However, existing multiple testing methods face challenges in efficiently incorporating complex side information,…

Methodology · Statistics 2025-02-11 Ziyi Liang , T. Tony Cai , Wenguang Sun , Yin Xia

Distribution shifts between sites can seriously degrade model performance since models are prone to exploiting unstable correlations. Thus, many methods try to find features that are stable across sites and discard unstable features.…

Machine Learning · Computer Science 2024-09-11 Minh Nguyen , Alan Q. Wang , Heejong Kim , Mert R. Sabuncu

Affine projection algorithm (APA) is a well-known algorithm in adaptive filtering applications such as audio echo cancellation. APA relies on three parameters: $P$ (projection order), $\mu$ (step size) and $\delta$ (regularization…

Information Theory · Computer Science 2023-10-16 Shirin Jalali , Carl Nuzman , Yue Sun

While reliable data-driven decision-making hinges on high-quality labeled data, the acquisition of quality labels often involves laborious human annotations or slow and expensive scientific measurements. Machine learning is becoming an…

Machine Learning · Statistics 2024-03-01 Tijana Zrnic , Emmanuel J. Candès

A great deal of effort has been devoted to reducing the risk of spurious scientific discoveries, from the use of sophisticated validation techniques, to deep statistical methods for controlling the false discovery rate in multiple…

Machine Learning · Computer Science 2016-03-03 Cynthia Dwork , Vitaly Feldman , Moritz Hardt , Toniann Pitassi , Omer Reingold , Aaron Roth

Adaptive experiments use preliminary analyses of the data to inform further course of action and are commonly used in many disciplines including medical and social sciences. Because the null hypothesis and experimental design are…

Methodology · Statistics 2026-05-26 Tobias Freidling , Qingyuan Zhao , Zijun Gao

Machine learning models are increasingly used to produce predictions that serve as input data in subsequent statistical analyses. For example, computer vision predictions of economic and environmental indicators based on satellite imagery…

Methodology · Statistics 2025-11-18 Dan M. Kluger , Kerri Lu , Tijana Zrnic , Sherrie Wang , Stephen Bates

Inference for the parameters indexing generalised linear models is routinely based on the assumption that the model is correct and a priori specified. This is unsatisfactory because the chosen model is usually the result of a data-adaptive…

Methodology · Statistics 2020-06-16 Stijn Vansteelandt , Oliver Dukes

Online Passive-Aggressive (PA) learning is a class of online margin-based algorithms suitable for a wide range of real-time prediction tasks, including classification and regression. PA algorithms are formulated in terms of deterministic…

Machine Learning · Statistics 2015-09-09 Arnold Salas , Stephen J. Roberts , Michael A. Osborne

The rapid proliferation of high-quality synthetic data -- generated by advanced AI models or collected as auxiliary data from related tasks -- presents both opportunities and challenges for statistical inference. This paper introduces a…

Methodology · Statistics 2026-02-19 Meshi Bashari , Yonghoon Lee , Roy Maor Lotan , Edgar Dobriban , Yaniv Romano

Deep neural networks demonstrate strong performance under aligned training-test distributions. However, real-world test data often exhibit domain shifts. Test-Time Adaptation (TTA) addresses this challenge by adapting the model to test data…

Artificial Intelligence · Computer Science 2025-08-27 Byung-Joon Lee , Jin-Seop Lee , Jee-Hyong Lee
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