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Medical imaging classifiers can achieve high predictive accuracy, but quantifying their uncertainty remains an unresolved challenge, which prevents their deployment in medical clinics. We present an algorithm that can modify any classifier…

Machine Learning · Computer Science 2024-08-12 Roy Hirsch , Jacob Goldberger

In clinical practice, medical image interpretation often involves multi-labeled classification, since the affected parts of a patient tend to present multiple symptoms or comorbidities. Recently, deep learning based frameworks have attained…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Jintai Chen , Hongyun Yu , Ruiwei Feng , Danny Z. Chen , Jian Wu

Although machine learning (ML) models of AI achieve high performances in medicine, they are not free of errors. Empowering clinicians to identify incorrect model recommendations is crucial for engendering trust in medical AI. Explainable AI…

Artificial Intelligence · Computer Science 2022-12-20 Isil Guzey , Ozlem Ucar , Nukhet Aladag Ciftdemir , Betul Acunas

The use of machine learning systems in clinical routine is still hampered by the necessity of a medical device certification and/or by difficulty to implement these systems in a clinic's quality management system. In this context, the key…

Medical Physics · Physics 2022-10-18 Lorenzo Mercolli , Axel Rominger , Kuangyu Shi

Mixed Integer Linear Programming (MILP) is a pillar of mathematical optimization that offers a powerful modeling language for a wide range of applications. During the past decades, enormous algorithmic progress has been made in solving…

Optimization and Control · Mathematics 2024-02-09 Lara Scavuzzo , Karen Aardal , Andrea Lodi , Neil Yorke-Smith

In an era of escalating cyber threats, malware poses significant risks to individuals and organizations, potentially leading to data breaches, system failures, and substantial financial losses. This study addresses the urgent need for…

Cryptography and Security · Computer Science 2025-01-28 Marzieh Esnaashari , Nima Moradi

Deep learning models have revolutionized the field of medical image analysis, due to their outstanding performances. However, they are sensitive to spurious correlations, often taking advantage of dataset bias to improve results for…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Diogo J. Araújo , M. Rita Verdelho , Alceu Bissoto , Jacinto C. Nascimento , Carlos Santiago , Catarina Barata

Neural network models have become the leading solution for a large variety of tasks, such as classification, language processing, protein folding, and others. However, their reliability is heavily plagued by adversarial inputs: small input…

Machine Learning · Computer Science 2022-10-04 Natan Levy , Guy Katz

The recent success of machine learning (ML) has been fueled by the increasing availability of computing power and large amounts of data in many different applications. However, the trustworthiness of the resulting models can be compromised…

Cryptography and Security · Computer Science 2024-03-11 Antonio Emanuele Cinà , Kathrin Grosse , Ambra Demontis , Battista Biggio , Fabio Roli , Marcello Pelillo

As cyber attacks continue to increase in frequency and sophistication, detecting malware has become a critical task for maintaining the security of computer systems. Traditional signature-based methods of malware detection have limitations…

Cryptography and Security · Computer Science 2024-03-05 Khatoon Mohammed

Human tissue and its constituent cells form a microenvironment that is fundamentally three-dimensional (3D). However, the standard-of-care in pathologic diagnosis involves selecting a few two-dimensional (2D) sections for microscopic…

Medical patient data is always multimodal. Images, text, age, gender, histopathological data are only few examples for different modalities in this context. Processing and integrating this multimodal data with deep learning based methods is…

Artificial Intelligence · Computer Science 2025-09-11 Christian Gapp , Elias Tappeiner , Martin Welk , Rainer Schubert

Brain-computer interfaces (BCIs) turn brain signals into functionally useful output, but they are not always accurate. A good Machine Learning classifier should be able to indicate how confident it is about a given classification, by giving…

Machine Learning · Computer Science 2025-07-17 Joris Suurmeijer , Ivo Pascal de Jong , Matias Valdenegro-Toro , Andreea Ioana Sburlea

Deep Learning sets the state-of-the-art in many challenging tasks showing outstanding performance in a broad range of applications. Despite its success, it still lacks robustness hindering its adoption in medical applications. Modeling…

Computer Vision and Pattern Recognition · Computer Science 2019-09-19 Agnieszka Tomczack , Nassir Navab , Shadi Albarqouni

Aim: To review how machine learning (ML) is applied to imaging biomarkers in neuro-oncology, in particular for diagnosis, prognosis, and treatment response monitoring. Materials and Methods: The PubMed and MEDLINE databases were searched…

Quantitative Methods · Quantitative Biology 2019-10-17 Thomas Booth , Matthew Williams , Aysha Luis , Jorge Cardoso , Ashkan Keyoumars , Haris Shuaib

In multi-label classification, machine learning encounters the challenge of domain generalization when handling tasks with distributions differing from the training data. Existing approaches primarily focus on vision object recognition and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Yuxin Qiao , Keqin Li , Junhong Lin , Rong Wei , Chufeng Jiang , Yang Luo , Haoyu Yang

Machine learning (ML) components are increasingly integrated into software products, yet their complexity and inherent uncertainty often lead to unintended and hazardous consequences, both for individuals and society at large. Despite these…

Software Engineering · Computer Science 2025-09-15 Yining Hong , Christopher S. Timperley , Christian Kästner

Developing artificial intelligence (AI) and machine learning (ML) models for medical imaging typically involves extensive training and testing on large datasets, consuming significant computational time, energy, and resources. There is a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Raj Hansini Khoiwal , Alan B. McMillan

The full acceptance of Deep Learning (DL) models in the clinical field is rather low with respect to the quantity of high-performing solutions reported in the literature. Particularly, end users are reluctant to rely on the rough…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Benjamin Lambert , Florence Forbes , Alan Tucholka , Senan Doyle , Harmonie Dehaene , Michel Dojat

In recent times, machine learning (ML) and artificial intelligence (AI) based systems have evolved and scaled across different industries such as finance, retail, insurance, energy utilities, etc. Among other things, they have been used to…

Machine Learning · Computer Science 2019-10-02 Akshay Arora , Arun Nethi , Priyanka Kharat , Vency Verghese , Grant Jenkins , Steve Miff , Vikas Chowdhry , Xiao Wang