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In critical decision support systems based on medical imaging, the reliability of AI-assisted decision-making is as relevant as predictive accuracy. Although deep learning models have demonstrated significant accuracy, they frequently…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Hua Xu , Julián D. Arias-Londoño , Juan I. Godino-Llorente

The comprehensive integration of machine learning healthcare models within clinical practice remains suboptimal, notwithstanding the proliferation of high-performing solutions reported in the literature. A predominant factor hindering…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Ling Huang , Su Ruan , Yucheng Xing , Mengling Feng

Medical image classification is a core task in computer-aided diagnosis (CAD), playing a pivotal role in early disease detection, treatment planning, and patient prognosis assessment. In ophthalmic practice, fluorescein fundus angiography…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Zhuonan Wang , Wenjie Yan , Wenqiao Zhang , Xiaohui Song , Jian Ma , Ke Yao , Yibo Yu , Beng Chin Ooi

High-accurate machine learning (ML) image classifiers cannot guarantee that they will not fail at operation. Thus, their deployment in safety-critical applications such as autonomous vehicles is still an open issue. The use of fault…

Artificial Intelligence · Computer Science 2021-10-05 Raul Sena Ferreira , Jean Arlat , Jeremie Guiochet , Hélène Waeselynck

In recent years, the number of machine learning (ML) technologies gaining regulatory approval for healthcare has increased significantly allowing them to be placed on the market. However, the regulatory frameworks applied to them were…

Machine Learning · Computer Science 2022-09-02 Shakir Laher , Carla Brackstone , Sara Reis , An Nguyen , Sean White , Ibrahim Habli

Recent works have shown that deep neural networks can achieve super-human performance in a wide range of image classification tasks in the medical imaging domain. However, these works have primarily focused on classification accuracy,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-10 Gongbo Liang , Yu Zhang , Xiaoqin Wang , Nathan Jacobs

The increasing use of machine-learning (ML) enabled systems in critical tasks fuels the quest for novel verification and validation techniques yet grounded in accepted system assurance principles. In traditional system development,…

Machine Learning · Computer Science 2020-02-11 Taejoon Byun , Sanjai Rayadurgam

Machine Learning (ML) models have gained popularity in medical imaging analysis given their expert level performance in many medical domains. To enhance the trustworthiness, acceptance, and regulatory compliance of medical imaging models…

Human-Computer Interaction · Computer Science 2025-06-06 Mischa Dombrowski , Andrea Prenner , Bernhard Kainz

Machine Learning has been applied to pathology images in research and clinical practice with promising outcomes. However, standard ML models often lack the rigorous evaluation required for clinical decisions. Machine learning techniques for…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Syed Ashar Javed , Dinkar Juyal , Zahil Shanis , Shreya Chakraborty , Harsha Pokkalla , Aaditya Prakash

Uncertainty quantification in automated image analysis is highly desired in many applications. Typically, machine learning models in classification or segmentation are only developed to provide binary answers; however, quantifying the…

Mixup~\cite{zhang2017mixup} is a recently proposed method for training deep neural networks where additional samples are generated during training by convexly combining random pairs of images and their associated labels. While simple to…

Machine Learning · Statistics 2020-01-08 Sunil Thulasidasan , Gopinath Chennupati , Jeff Bilmes , Tanmoy Bhattacharya , Sarah Michalak

Highly imbalanced datasets are ubiquitous in medical image classification problems. In such problems, it is often the case that rare classes associated to less prevalent diseases are severely under-represented in labeled databases,…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Adrian Galdran , Gustavo Carneiro , Miguel A. González Ballester

Classification and segmentation are crucial in medical image analysis as they enable accurate diagnosis and disease monitoring. However, current methods often prioritize the mutual learning features and shared model parameters, while…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Kai Ren , Ke Zou , Xianjie Liu , Yidi Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Machine Learning (ML) is increasingly used to implement advanced applications with non-deterministic behavior, which operate on the cloud-edge continuum. The pervasive adoption of ML is urgently calling for assurance solutions assessing…

Machine Learning · Computer Science 2023-10-24 Marco Anisetti , Claudio A. Ardagna , Nicola Bena , Ernesto Damiani

Quantum technologies are rapidly advancing as image classification tasks grow more complex due to large image volumes and extensive parameter updates required by traditional machine learning models. Quantum Machine Learning (QML) offers a…

Quantum Physics · Physics 2025-04-29 Md Farhan Shahriyar , Gazi Tanbhir

Advanced classification algorithms are being increasingly used in safety-critical applications like health-care, engineering, etc. In such applications, miss-classifications made by ML algorithms can result in substantial financial or…

Machine Learning · Computer Science 2024-12-06 Disha Ghandwani , Neeraj Sarna , Yuanyuan Li , Yang Lin

Uncertainty estimation of trained deep learning networks is valuable for optimizing learning efficiency and evaluating the reliability of network predictions. In this paper, we propose a method for estimating uncertainty in deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Hansang Lee , Haeil Lee , Helen Hong , Junmo Kim

Machine learning (ML) has recently created many new success stories. Hence, there is a strong motivation to use ML technology in software-intensive systems, including safety-critical systems. This raises the issue of safety verification of…

Software Engineering · Computer Science 2020-07-01 Hermann Kaindl , Stefan Kramer

Image classification with deep neural networks has seen a surge of technological breakthroughs with promising applications in areas such as face recognition, medical imaging, and autonomous driving. In engineering problems, however, such as…

Computer Vision and Pattern Recognition · Computer Science 2022-07-21 Hongjiang Li , Huanyi Shui , Alemayehu Admasu , Praveen Narayanan , Devesh Upadhyay

Breast cancer (BC) remains a significant global health challenge, with personalized treatment selection complicated by the disease's molecular and clinical heterogeneity. BC treatment decisions rely on various patient-specific clinical…

Applications · Statistics 2025-07-10 Md Nahid Hasan , Md Monzur Murshed , Md Mahadi Hasan , Faysal A. Chowdhury
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