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Every day, users generate digital traces (e.g., social media posts, chats, and online interactions) that are inherently timestamped and may reflect aspects of their mental state. These traces can be organized into temporal trajectories that…

Artificial Intelligence · Computer Science 2026-05-15 Loris Belcastro , Francesco Gervino , Fabrizio Marozzo , Domenico Talia , Paolo Trunfio

In the context of digital therapy interventions, such as internet-delivered Cognitive Behavioral Therapy (iCBT) for the treatment of depression and anxiety, extensive research has shown how the involvement of a human supporter or coach, who…

Human-Computer Interaction · Computer Science 2021-11-15 Anja Thieme

Large Language Models(LLMs) excel in general tasks but struggle in specialized domains like healthcare due to limited domain-specific knowledge.Supervised Fine-Tuning(SFT) data construction for domain adaptation often relies on heuristic…

Machine Learning · Computer Science 2025-09-19 Hongxin Ding , Yue Fang , Runchuan Zhu , Xinke Jiang , Jinyang Zhang , Yongxin Xu , Xu Chu , Junfeng Zhao , Yasha Wang

Attention mechanisms have played a crucial role in the development of complex architectures such as Transformers in natural language processing. However, Transformers remain hard to interpret and are considered as black-boxes. This paper…

Machine Learning · Computer Science 2023-03-28 Milan Bhan , Nina Achache , Victor Legrand , Annabelle Blangero , Nicolas Chesneau

Artificial intelligence-augmented technology represents a considerable opportunity for improving healthcare delivery. Significant progress has been made to demonstrate the value of complex models to enhance clinicians` efficiency in…

Human-Computer Interaction · Computer Science 2025-04-08 Mohammad Golam Kibria , Lauren Kucirka , Javed Mostafa

Recent studies have demonstrated promising performance of ChatGPT and GPT-4 on several medical domain tasks. However, none have assessed its performance using a large-scale real-world electronic health record database, nor have evaluated…

Computation and Language · Computer Science 2023-07-18 Jingqing Zhang , Kai Sun , Akshay Jagadeesh , Mahta Ghahfarokhi , Deepa Gupta , Ashok Gupta , Vibhor Gupta , Yike Guo

International Classification of Diseases (ICD) coding plays an important role in systematically classifying morbidity and mortality data. In this study, we propose a hierarchical label-wise attention Transformer model (HiLAT) for the…

Machine Learning · Computer Science 2022-10-04 Leibo Liu , Oscar Perez-Concha , Anthony Nguyen , Vicki Bennett , Louisa Jorm

Conversational diagnosis requires multi-turn history-taking, where an agent asks clarifying questions to refine differential diagnoses under incomplete information. Existing approaches often rely on the parametric knowledge of a model or…

Artificial Intelligence · Computer Science 2026-02-04 Jeongmoon Won , Seungwon Kook , Yohan Jo

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition whose rising prevalence places increasing demands on a lengthy diagnostic process. Machine learning (ML) has shown promise in automating ASD diagnosis, but most…

Artificial Intelligence · Computer Science 2025-12-09 Gondy Leroy , Prakash Bisht , Sai Madhuri Kandula , Nell Maltman , Sydney Rice

Current Virtual Mental Health Assistants (VMHAs) provide counseling and suggestive care. They refrain from patient diagnostic assistance because they lack training in safety-constrained and specialized clinical process knowledge. In this…

Computation and Language · Computer Science 2023-06-05 Kaushik Roy , Manas Gaur , Misagh Soltani , Vipula Rawte , Ashwin Kalyan , Amit Sheth

Objective: Large Language Models (LLMs) demonstrate significant capabilities in medical text understanding and generation. However, their diagnostic reliability in complex clinical scenarios remains limited. This study aims to enhance LLMs'…

Computation and Language · Computer Science 2025-08-04 Peixian Li , Yu Tian , Ruiqi Tu , Chengkai Wu , Jingjing Ren , Jingsong Li

Recent research leverages large language models (LLMs) for early mental health detection, such as depression, often optimized with machine-generated data. However, their detection may be subject to unknown weaknesses. Meanwhile, quality…

Computation and Language · Computer Science 2025-05-26 Zongru Shao , Xin Wang , Zhanyang Liu , Chenhan Wang , K. P. Subbalakshmi

We introduce MentalChat16K, an English benchmark dataset combining a synthetic mental health counseling dataset and a dataset of anonymized transcripts from interventions between Behavioral Health Coaches and Caregivers of patients in…

Machine Learning · Computer Science 2025-06-03 Jia Xu , Tianyi Wei , Bojian Hou , Patryk Orzechowski , Shu Yang , Ruochen Jin , Rachael Paulbeck , Joost Wagenaar , George Demiris , Li Shen

Intensive Care in-hospital mortality prediction has various clinical applications. Neural prediction models, especially when capitalising on clinical notes, have been put forward as improvement on currently existing models. However, to be…

Computation and Language · Computer Science 2022-12-14 Miguel Rios , Ameen Abu-Hanna

The classical approach to detecting depression from vision emphasizes interpretable features, such as facial expression, and classifiers such as the Support Vector Machine (SVM). With the advent of deep learning, there has been a shift in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Maneesh Bilalpur , Saurabh Hinduja , Sonish Sivarajkumar , Nicholas Allen , Yanshan Wang , Itir Onal Ertugrul , Jeffrey F. Cohn

Clinical decision-making requires synthesizing heterogeneous evidence, including patient histories, clinical guidelines, and trajectories of comparable cases. While large language models (LLMs) offer strong reasoning capabilities, they…

Artificial Intelligence · Computer Science 2026-03-03 Shuheng Chen , Namratha Patil , Haonan Pan , Angel Hsing-Chi Hwang , Yao Du , Ruishan Liu , Jieyu Zhao

Mental disorders, such as anxiety and depression, have become a global concern that affects people of all ages. Early detection and treatment are crucial to mitigate the negative effects these disorders can have on daily life. Although…

Computers and Society · Computer Science 2025-02-05 Jinghui Qin , Changsong Liu , Tianchi Tang , Dahuang Liu , Minghao Wang , Qianying Huang , Rumin Zhang

After performing comparison of the performance of seven different machine learning models on detection depression tasks to show that the choice of features is essential, we compare our methods and results with the published work of other…

Machine Learning · Statistics 2020-06-12 Milena Čukić Radenković , David Pokrajac , Victoria Lopez

Major depressive disorder is a debilitating disease affecting 264 million people worldwide. While many antidepressant medications are available, few clinical guidelines support choosing among them. Decision support tools (DSTs) embodying…

Recent success in Artificial Intelligence (AI) and Machine Learning (ML) allow problem solving automatically without any human intervention. Autonomous approaches can be very convenient. However, in certain domains, e.g., in the medical…

Artificial Intelligence · Computer Science 2021-03-03 Andreas Holzinger , André Carrington , Heimo Müller
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