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Uncertainty of labels in clinical data resulting from intra-observer variability can have direct impact on the reliability of assessments made by deep neural networks. In this paper, we propose a method for modelling such uncertainty in the…

Electrocardiography (ECG) signal is a highly applied measurement for individual heart condition, and much effort have been endeavored towards automatic heart arrhythmia diagnosis based on machine learning. However, traditional machine…

Signal Processing · Electrical Eng. & Systems 2021-11-01 Ziyu Liu , Xiang Zhang

Most estimators collapse all uncertainty modes into a single confidence score, preventing reliable reasoning about when to allocate more compute or adjust inference. We introduce Uncertainty-Guided Inference-Time Selection, a lightweight…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Divake Kumar , Patrick Poggi , Sina Tayebati , Devashri Naik , Nilesh Ahuja , Amit Ranjan Trivedi

The classification of electrocardiogram (ECG) signals is crucial for early detection of arrhythmias and other cardiac conditions. However, despite advances in machine learning, many studies fail to follow standardization protocols, leading…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Guilherme Silva , Pedro Silva , Gladston Moreira , Vander Freitas , Jadson Gertrudes , Eduardo Luz

AI computation in healthcare faces significant challenges when clinical datasets are limited and heterogeneous. Integrating datasets from multiple sources and different equipments is critical for effective AI computation but is complicated…

Signal Processing · Electrical Eng. & Systems 2025-04-07 Baozhuo Su , Qingli Dou , Kang Liu , Zhengxian Qu , Jerry Deng , Ting Tan , Yanan Gu

Certain cancer types, notably pancreatic cancer, are difficult to detect at an early stage, motivating robust biomarker-based screening. Liquid biopsies enable non-invasive monitoring of circulating biomarkers, but typical machine learning…

Machine Learning · Computer Science 2025-11-21 Chongmin Lee , Jihie Kim

Deep learning models for pulmonary disease screening from Computed Tomography (CT) scans promise to alleviate the immense workload on radiologists. Still, their high computational cost, stemming from processing entire 3D volumes, remains a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-19 Qian Shao , Bang Du , Yixuan Wu , Zepeng Li , Qiyuan Chen , Qianqian Tang , Jian Wu , Jintai Chen , Hongxia Xu

Mathematical modeling in systems toxicology enables a comprehensive understanding of the effects of pharmaceutical substances on cardiac health. However, the complexity of these models limits their widespread application in early drug…

Deep neural networks (DNN) are prone to miscalibrated predictions, often exhibiting a mismatch between the predicted output and the associated confidence scores. Contemporary model calibration techniques mitigate the problem of…

Machine Learning · Computer Science 2022-12-21 Ramya Hebbalaguppe , Rishabh Patra , Tirtharaj Dash , Gautam Shroff , Lovekesh Vig

This paper introduces a framework for uncertainty quantification in regression models defined in metric spaces. Leveraging a newly defined notion of homoscedasticity, we develop a conformal prediction algorithm that offers finite-sample…

Machine Learning · Statistics 2025-07-22 Gábor Lugosi , Marcos Matabuena

Reasonably and effectively monitoring arrhythmias through ECG signals has significant implications for human health. With the development of deep learning, numerous ECG classification algorithms based on deep learning have emerged. However,…

Signal Processing · Electrical Eng. & Systems 2023-08-28 Ninghao Pu , Zhongxing Wu , Ao Wang , Hanshi Sun , Zijin Liu , Hao Liu

Predicting the health risks of patients using Electronic Health Records (EHR) has attracted considerable attention in recent years, especially with the development of deep learning techniques. Health risk refers to the probability of the…

Machine Learning · Computer Science 2022-11-15 Yuxi Liu , Shaowen Qin , Antonio Jimeno Yepes , Wei Shao , Zhenhao Zhang , Flora D. Salim

Artificial intelligence holds strong potential to support clinical decision making in intensive care units where timely and accurate risk assessment is critical. However, many existing models focus on isolated outcomes or limited data…

Machine learning (ML) applied to routine patient monitoring within intensive care units (ICUs) has the potential to improve care by providing clinicians with novel insights into each patient's health and expected response to interventions.…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Thomas Kite , Uzair Tahamid Siam , Brian Ayers , Nicholas Houstis , Aaron D Aguirre

This paper addresses a multi-label predictive fault classification problem for multidimensional time-series data. While fault (event) detection problems have been thoroughly studied in literature, most of the state-of-the-art techniques…

Machine Learning · Computer Science 2020-01-29 Wenyu Zhang , Devesh K. Jha , Emil Laftchiev , Daniel Nikovski

In this work, we propose a multi-task recurrent neural network with attention mechanism for predicting cardiovascular events from electronic health records (EHRs) at different time horizons. The proposed approach is compared to a standard…

While the volume of electronic health records (EHR) data continues to grow, it remains rare for hospital systems to capture dense physiological data streams, even in the data-rich intensive care unit setting. Instead, typical EHR records…

Machine Learning · Computer Science 2018-12-04 Satya Narayan Shukla , Benjamin M. Marlin

Background: The huge quantity of data produced in Biomedical research needs sophisticated algorithmic methodologies for its storage, analysis, and processing. High Performance Computing (HPC) appears as a magic bullet in this challenge.…

Quantitative Methods · Quantitative Biology 2016-10-19 Gianni D'Angelo , Salvatore Rampone

Artificial intelligence (AI) systems accelerate medical workflows and improve diagnostic accuracy in healthcare, serving as second-opinion systems. However, the unpredictability of AI errors poses a significant challenge, particularly in…

Electrocardiogram (ECG) is the most widely used diagnostic tool to monitor the condition of the cardiovascular system. Deep neural networks (DNNs), have been developed in many research labs for automatic interpretation of ECG signals to…

Signal Processing · Electrical Eng. & Systems 2020-12-02 Linhai Ma , Liang Liang