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Visual exploration of large multidimensional datasets has seen tremendous progress in recent years, allowing users to express rich data queries that produce informative visual summaries, all in real time. Techniques based on data cubes are…

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

Understanding how receptive fields emerge and organize within brain networks and how neural dynamics couple with stimuli space is fundamental to neuroscience. Models often rely on fine-tuning connectivity to match empirical data, which may…

Neurons and Cognition · Quantitative Biology 2026-01-07 Vasilii Tiselko , Alexander Gorsky , Yuri Dabaghian

Modeling car-following behavior is fundamental to microscopic traffic simulation, yet traditional deterministic models often fail to capture the full extent of variability and unpredictability in human driving. While many modern approaches…

Applications · Statistics 2026-01-30 Chengyuan Zhang , Zhengbing He , Cathy Wu , Lijun Sun

Although individual neurons and neural populations exhibit the phenomenon of representational drift, perceptual and behavioral outputs of many neural circuits can remain stable across time scales over which representational drift is…

The distinct timescales of synaptic plasticity and neural activity dynamics play an important role in the brain's learning and memory systems. Activity-dependent plasticity reshapes neural circuit architecture, determining spontaneous and…

Neurons and Cognition · Quantitative Biology 2023-06-30 Heather L Cihak , Zachary P Kilpatrick

The human visual system is an intricate network of brain regions that enables us to recognize the world around us. Despite its abundant lateral and feedback connections, object processing is commonly viewed and studied as a feedforward…

Neurons and Cognition · Quantitative Biology 2019-10-09 Tim C Kietzmann , Courtney J Spoerer , Lynn Sörensen , Radoslaw M Cichy , Olaf Hauk , Nikolaus Kriegeskorte

A pressing scientific challenge is to understand how brains work. Of particular interest is the neocortex,the part of the brain that is especially large in humans, capable of handling a wide variety of tasks including visual, auditory,…

Neural and Evolutionary Computing · Computer Science 2016-09-03 Peter U. Diehl , Matthew Cook

Active Brownian particles (ABPs) function as self-driving agents that display non-equilibrium behavior through their pairwise interactions which lead to phase separation and vortex patterns in both soft matter and living systems. A…

Soft Condensed Matter · Physics 2025-09-09 Sadra Saremi , Amirhossein Ahmadkhan Kordbacheh

Brain connectomics is still largely dominated by pairwise-based models, such as graphs, which cannot represent circulatory or higher-order functional interactions. In this paper, we propose a multimodal framework based on Topological Signal…

Neurons and Cognition · Quantitative Biology 2026-04-01 Breno C. Bispo , Stefania Sardellitti , Juliano B. Lima , Fernando A. N. Santos

We propose a probabilistic framework for developing computational models of biological neural systems. In this framework, physiological recordings are viewed as discrete-time partial observations of an underlying continuous-time stochastic…

Neurons and Cognition · Quantitative Biology 2026-02-10 Ahmed ElGazzar , Marcel van Gerven

Recent work has demonstrated that complex visual stimuli can be decoded from human brain activity using deep generative models, offering new ways to probe how the brain represents real-world scenes. However, many existing approaches first…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Pinyuan Feng , Hossein Adeli , Wenxuan Guo , Fan Cheng , Ethan Hwang , Nikolaus Kriegeskorte

Brain foundation models (BFMs) have emerged as a transformative paradigm in computational neuroscience, offering a revolutionary framework for processing diverse neural signals across different brain-related tasks. These models leverage…

Machine Learning · Computer Science 2025-07-22 Xinliang Zhou , Chenyu Liu , Zhisheng Chen , Kun Wang , Yi Ding , Ziyu Jia , Qingsong Wen

Understanding the dynamics of large-scale brain models remains a central challenge due to the inherent complexity of these systems. In this work, we explore the emergence of complex spatiotemporal patterns in a large scale-brain model…

Neurons and Cognition · Quantitative Biology 2025-12-04 Rosa Maria Delicado , Gemma Huguet , Pau Clusella

Representing dynamical systems through data-driven universal spaces has proven effective; however, achieving this universality for human brain activity remains a significant challenge, further aggravated by diverse cognitive states and…

Quantitative Methods · Quantitative Biology 2026-05-06 Ronghua Zheng , Chengyuan Qian , Weiyang Ding

This paper considers neural representation through the lens of active inference, a normative framework for understanding brain function. It delves into how living organisms employ generative models to minimize the discrepancy between…

Neurons and Cognition · Quantitative Biology 2023-10-24 Giovanni Pezzulo , Leo D'Amato , Francesco Mannella , Matteo Priorelli , Toon Van de Maele , Ivilin Peev Stoianov , Karl Friston

This paper introduces TVB C++, a streamlined and fast C++ Back-End for The Virtual Brain (TVB), a renowned platform and a benchmark tool for full-brain simulation. TVB C++ is engineered with speed as a primary focus while retaining the…

Neurons and Cognition · Quantitative Biology 2024-06-26 Ignacio Martín , Gorka Zamora , Jan Fousek , Michael Schirner , Petra Ritter , Viktor Jirsa , Gustavo Deco , Gustavo Patow

Understanding how the human brain represents visual concepts, and in which brain regions these representations are encoded, remains a long-standing challenge. Decades of work have advanced our understanding of visual representations, yet…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Navve Wasserman , Matias Cosarinsky , Yuval Golbari , Aude Oliva , Antonio Torralba , Tamar Rott Shaham , Michal Irani

We propose a neural network model of multi-neuron interacting system that simulates neurons to interact each other through the surroundings of neuronal cell bodies. We physically model the neuronal cell surroundings, include the dendrites,…

Neurons and Cognition · Quantitative Biology 2021-07-05 Yu-Juan Sun , Wei-Min Zhang

We deal with the problem of bridging the gap between two scales in neuronal modeling. At the first (microscopic) scale, neurons are considered individually and their behavior described by stochastic differential equations that govern the…

Biological Physics · Physics 2010-11-09 Olivier Faugeras , Jonathan Touboul , Bruno Cessac