Related papers: A nonlocal equation describing tumor growth
Both compressible and incompressible porous medium models are used in the literature to describe the mechanical properties of living tissues. These two classes of models can be related using a stiff pressure law. In the incompressible…
In the present article the diffusion equation is used to model the spatio-temporal dynamics of a tumor, taking into account the heterogeneous of the medium. This approach makes it possible to take into account the complex geometric shape of…
The main target of this paper is to present an efficient method to solve a nonlinear free boundary mathematical model of prostate tumor. This model consists of two parabolics, one elliptic and one ordinary differential equations that are…
Cancer is viewed as a multistep process whereby a normal cell is transformed into a cancer cell through the acquisition of mutations. We reduce the complexities of cancer progression to a simple set of underlying rules that govern the…
For tumor growth, the morphological instability provides a mechanism for invasion via tumor fingering and fragmentation. This work considers the asymptotic stability of a free boundary tumor model with a periodic supply of external…
We consider a mathematical model for the evolutionary dynamics of tumour cells in vascularised tumours under chemotherapy. The model comprises a system of coupled partial integro-differential equations for the phenotypic distribution of…
In this paper, we study a nonlinearly coupled initial-boundary value problem describing the evolution of brain tumor growth including lactate metabolism. In our modeling approach, we also take into account the viscoelastic properties of the…
Cancer stem cells have been shown to be critical to the development of a variety of solid cancers. The precise interplay mechanisms between cancer stem cells and the rest of a tissue are still not elucidated. To shed light on the…
This paper presents a model for tumor growth using nonlocal velocity. We establish some results on the existence and uniqueness of the solution for a nonlocal tumor growth model. Many experiences show that tumor spheroid can be invariant by…
In this paper, we study a tumor growth model where the growth is driven by nutrient availability and the tumor expands according to Darcy's law with a mechanical pressure resulting from the incompressibility of the cells. Our focus is on…
In this paper we study the onset of angiogenesis and derive a new model to describe it. This new model takes the form of a nonlocal Burgers equation with both diffusive and dispersive terms. For a particular value of the parameters, the…
In this paper we study the rigorous sharp interface limit of a diffuse interface model related to the dynamics of tumor growth, when a parameter $\epsilon$, representing the interface thickness between the tumorous and non tumorous cells,…
We report on a simple model of spatial extend anti-tumor system with a fluctuation in growth rate, which can undergo a nonequilibrium phase transition. Three states as excited, sub-excited and non-excited states of a tumor are defined to…
We develop an existence and regularity theory for solutions to a geometric free boundary problem motivated by models of tumor growth. In this setting, the tumor invades an accessible region $D$, its motion is directed along a constant…
Williams and Bjerknes proposed a simple stochastic growth model to describe the tumor growth in the basal layer of an epithelium. In this work we generalize this model by including the possibility of saturation in the tumor growth as it is…
Formulating tumor models that predict growth under therapy is vital for improving patient-specific treatment plans. In this context, we present our recent work on simulating non-small-scale cell lung cancer (NSCLC) in a simple,…
In this paper, we investigate the tumor instability by employing both analytical and numerical techniques to validate previous results and extend the analytical findings presented in a prior study by Feng et al 2023. Building upon the…
Although the immune response is often regarded as acting to suppress tumor growth, it is now clear that it can be both stimulatory and inhibitory. The interplay between these competing influences has complex implications for tumor…
Recently, we have proposed a nutrient-limited model for the avascular growth of tumors including cell proliferation, motility and death \cite{jr}, that, qualitatively reproduces commonly observed morphologies for carcinomas {\it in situ}.…
Most human tumors result from the accumulation of multiple genetic and epigenetic alterations in a single cell. Mutations that confer a fitness advantage to the cell are known as driver mutations and are causally related to tumorigenesis.…