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Biomedical imaging and RNA sequencing with single-cell resolution improves our understanding of white blood cell diseases like leukemia. By combining morphological and transcriptomic data, we can gain insights into cellular functions and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Gizem Mert , Ario Sadafi , Raheleh Salehi , Nassir Navab , Carsten Marr

Audio-based disease prediction is emerging as a promising supplement to traditional medical diagnosis methods, facilitating early, convenient, and non-invasive disease detection and prevention. Multimodal fusion, which integrates features…

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) derived from somatic cells (SCs) provide promising resources for regenerative medicine and medical research, leading to a daily identification of new cell lines.…

Quantitative Methods · Quantitative Biology 2013-02-15 Anyou Wang

Until recently, transcriptomics was limited to bulk RNA sequencing, obscuring the underlying expression patterns of individual cells in favor of a global average. Thanks to technological advances, we can now profile gene expression across…

Quantitative Methods · Quantitative Biology 2018-11-30 Miriam Shiffman , William T. Stephenson , Geoffrey Schiebinger , Jonathan Huggins , Trevor Campbell , Aviv Regev , Tamara Broderick

To overcome the imbalanced multimodal learning problem, where models prefer the training of specific modalities, existing methods propose to control the training of uni-modal encoders from different perspectives, taking the inter-modal…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yake Wei , Siwei Li , Ruoxuan Feng , Di Hu

In this paper, an innovative multi-modal deep learning model is proposed to deeply integrate heterogeneous information from medical images and clinical reports. First, for medical images, convolutional neural networks were used to extract…

Machine Learning · Computer Science 2024-05-29 Ziyan Yao , Fei Lin , Sheng Chai , Weijie He , Lu Dai , Xinghui Fei

The ability to measure the transcriptomes of single cells has only been feasible for a few years, and is becoming an extremely popular assay. While many types of analysis and questions can be answered using single cell RNA-sequencing, a…

Genomics · Quantitative Biology 2017-08-09 Valentine Svensson , Roser Vento-Tormo , Sarah A Teichmann

A rigorous methodology is proposed to study cell division data consisting in several observed genealogical trees of possibly different shapes. The procedure takes into account missing observations, data from different trees, as well as the…

Applications · Statistics 2013-04-15 Benoîte de Saporta , Anne Gégout Petit , Laurence Marsalle

The increasing need for accurate and unified analysis of diverse biological signals, such as ECG and EEG, is paramount for comprehensive patient assessment, especially in synchronous monitoring. Despite advances in multi-sensor fusion, a…

Signal Processing · Electrical Eng. & Systems 2025-07-18 Mohammed Guhdar , Ramadhan J. Mstafa , Abdulhakeem O. Mohammed

Our knowledge of how individual cells self-organize to form complex multicellular systems is being revolutionized by a data outburst, coming from high-throughput experimental breakthroughs such as single-cell RNA sequencing and spatially…

Cell Behavior · Quantitative Biology 2021-04-20 Gabriel Torregrosa , Jordi Garcia-Ojalvo

Understanding cell identity and function through single-cell level sequencing data remains a key challenge in computational biology. We present a novel framework that leverages gene-specific textual annotations from the NCBI Gene database…

Genomics · Quantitative Biology 2025-05-14 Douglas Jiang , Zilin Dai , Luxuan Zhang , Qiyi Yu , Haoqi Sun , Feng Tian

This study proposes a novel approach combining Multimodal Deep Learning with intrinsic eXplainable Artificial Intelligence techniques to predict pathological response in non-small cell lung cancer patients undergoing neoadjuvant therapy.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Alice Natalina Caragliano , Claudia Tacconi , Carlo Greco , Lorenzo Nibid , Edy Ippolito , Michele Fiore , Giuseppe Perrone , Sara Ramella , Paolo Soda , Valerio Guarrasi

Multimodal clinical prediction is widely used to integrate heterogeneous data such as Electronic Health Records (EHR) and biosignals. However, existing methods tend to rely on static modality integration schemes and simple fusion…

Machine Learning · Computer Science 2026-01-16 Jongseok Kim , Seongae Kang , Jonghwan Shin , Yuhan Lee , Ohyun Jo

Multi-modal learning is a fast growing area in artificial intelligence. It tries to help machines understand complex things by combining information from different sources, like images, text, and audio. By using the strengths of each…

Machine Learning · Computer Science 2025-12-22 Qihang Jin , Enze Ge , Yuhang Xie , Hongying Luo , Junhao Song , Ziqian Bi , Chia Xin Liang , Jibin Guan , Joe Yeong , Xinyuan Song , Junfeng Hao

A model of multicellular systems with several types of cells is developed from the phase field model. The model is presented as a set of partial differential equations of the field variables, each of which expresses the shape of one cell.…

Biological Physics · Physics 2015-05-30 Makiko Nonomura

We are perceiving and communicating with the world in a multisensory manner, where different information sources are sophisticatedly processed and interpreted by separate parts of the human brain to constitute a complex, yet harmonious and…

Computer Vision and Pattern Recognition · Computer Science 2024-06-12 Ye Zhu , Yu Wu , Nicu Sebe , Yan Yan

Multiplexed immuno-fluorescence tissue imaging, allowing simultaneous detection of molecular properties of cells, is an essential tool for characterizing the complex cellular mechanisms in translational research and clinical practice. New…

Multimodal data arise in various applications where information about the same phenomenon is acquired from multiple sensors and across different imaging modalities. Learning from multimodal data is of great interest in machine learning and…

Machine Learning · Statistics 2022-01-20 Li Peide , Seyyid Emre Sofuoglu , Tapabrata Maiti , Selin Aviyente

Taxonomic classification in biodiversity research involves organizing biological specimens into structured hierarchies based on evidence, which can come from multiple modalities such as images and genetic information. We investigate whether…

Modern data analytics take advantage of ensemble learning and transfer learning approaches to tackle some of the most relevant issues in data analysis, such as lack of labeled data to use to train the analysis models, sparsity of the…

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