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Hippocampus segmentation plays a key role in diagnosing various brain disorders such as Alzheimer's disease, epilepsy, multiple sclerosis, cancer, depression and others. Nowadays, segmentation is still mainly performed manually by…
Based on recent health statistics, there are several thousands of people with limb disability and gait disorders that require a medical assistance. A robot assisted rehabilitation therapy can help them recover and return to a normal life.…
Agitation is one of the most prevalent symptoms in people with dementia (PwD) that can place themselves and the caregiver's safety at risk. Developing objective agitation detection approaches is important to support health and safety of PwD…
Sleep studies are imperative to recapitulate phenotypes associated with sleep loss and uncover mechanisms contributing to psychopathology. Most often, investigators manually classify the polysomnography into vigilance states, which is…
Dementia is characterized by a decline in memory and thinking that is significant enough to impair function in activities of daily living. Patients seen in dementia specialty clinics are highly heterogeneous with a variety of different…
To optimize mobile health interventions and advance domain knowledge on intervention design, it is critical to understand how the intervention effect varies over time and with contextual information. This study aims to assess how a push…
While depression has been studied via multimodal non-verbal behavioural cues, head motion behaviour has not received much attention as a biomarker. This study demonstrates the utility of fundamental head-motion units, termed \emph{kinemes},…
Introduction Schizophrenia is a severe mental disorder, and early diagnosis is key to improving outcomes. Its complexity makes predicting onset and progression challenging. EEG has emerged as a valuable tool for studying schizophrenia, with…
Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…
Clinical electroencephalography is routinely used to evaluate patients with diverse and often overlapping neurological conditions, yet interpretation remains manual, time-intensive, and variable across experts. While automated EEG analysis…
Sleep behaviour and in-bed movements contain rich information on the neurophysiological health of people, and have a direct link to the general well-being and quality of life. Standard clinical practices rely on polysomnography for sleep…
We frequently encounter multiple series that are temporally correlated in our surroundings, such as EEG data to examine alterations in brain activity or sensors to monitor body movements. Segmentation of multivariate time series data is a…
Recently, various deep neural networks have been applied to classify electroencephalogram (EEG) signal. EEG is a brain signal that can be acquired in a non-invasive way and has a high temporal resolution. It can be used to decode the…
Behavioral changes are the earliest signs of a mental disorder, but arguably, the dynamics of brain function gets affected even earlier. Subsequently, spatio-temporal structure of disorder-specific dynamics is crucial for early diagnosis…
Clinical methods that assess gait in Parkinson's Disease (PD) are mostly qualitative. Quantitative methods necessitate costly instrumentation or cumbersome wearable devices, which limits their usability. Only few of these methods can…
Activity recognition computer vision algorithms can be used to detect the presence of autism-related behaviors, including what are termed "restricted and repetitive behaviors", or stimming, by diagnostic instruments. The limited data that…
Learning and understanding the typical patterns in the daily activities and routines of people from low-level sensory data is an important problem in many application domains such as building smart environments, or providing intelligent…
Mental disorders including depression, anxiety, and other neurological disorders pose a significant global challenge, particularly among individuals exhibiting social avoidance tendencies. This study proposes a hybrid approach by leveraging…
As a mental disorder progresses, it may affect brain structure, but brain function expressed in brain dynamics is affected much earlier. Capturing the moment when brain dynamics express the disorder is crucial for early diagnosis. The…
Longitudinal patient data has the potential to improve clinical risk stratification models for disease. However, chronic diseases that progress slowly over time are often heterogeneous in their clinical presentation. Patients may progress…