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Parkinson's disease (PD) is a common neurodegenerative disorder with a poorly understood physiopathology and no established biomarkers for the diagnosis of early stages and for prediction of disease progression. Several neuroimaging…

Parkinson's Disease (PD) is a chronic and progressive neurological disorder that results in rigidity, tremors and postural instability. There is no definite medical test to diagnose PD and diagnosis is mostly a clinical exercise. Although…

Image and Video Processing · Electrical Eng. & Systems 2021-07-28 Shanmukh Alle , U. Deva Priyakumar

In pathology, the rarity of certain diseases and the complexity in annotating pathological images significantly hinder the creation of extensive, high-quality datasets. This limitation impedes the progress of deep learning-assisted…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Hao Quan , Xinjia Li , Dayu Hu , Tianhang Nan , Xiaoyu Cui

Traditional Recurrent Neural Networks (RNNs) and Long Short-Term Memory (LSTM) units operate on discrete time steps, often failing to capture the fluid temporal dynamics of real-world physical processes. Liquid Neural Networks (LNNs),…

Machine Learning · Computer Science 2026-05-28 Ye Kyaw Thu , Thazin Myint Oo , Thepchai Supnithi

Parkinsons Disease is a neurological disorder and prevalent in elderly people. Traditional ways to diagnose the disease rely on in-person subjective clinical evaluations on the quality of a set of activity tests. The high-resolution…

Machine Learning · Computer Science 2020-10-16 Weijian Li , Wei Zhu , E. Ray Dorsey , Jiebo Luo

Limited accessibility to neurological care leads to underdiagnosed Parkinson's Disease (PD), preventing early intervention. Existing AI-based PD detection methods primarily focus on unimodal analysis of motor or speech tasks, overlooking…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Md Saiful Islam , Tariq Adnan , Jan Freyberg , Sangwu Lee , Abdelrahman Abdelkader , Meghan Pawlik , Cathe Schwartz , Karen Jaffe , Ruth B. Schneider , E Ray Dorsey , Ehsan Hoque

Parkinson disease is the second most common neurodegenerative disorder, as reported by the World Health Organization. In this paper, we propose a direct three-Class PD classification using two different modalities, namely, MRI and DTI. The…

Computer Vision and Pattern Recognition · Computer Science 2023-07-07 Sushanta Kumar Sahu , Ananda S. Chowdhury

Parkinson's Disease (PD) affects millions globally, impacting movement. Prior research utilized deep learning for PD prediction, primarily focusing on medical images, neglecting the data's underlying manifold structure. This work proposes a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Jun-En Ding , Chien-Chin Hsu , Feng Liu

Gesture recognition is a very essential technology for many wearable devices. While previous algorithms are mostly based on statistical methods including the hidden Markov model, we develop two dynamic hand gesture recognition techniques…

Computer Vision and Pattern Recognition · Computer Science 2016-08-16 Sungho Shin , Wonyong Sung

This paper presents a method for building patient-based networks that we call Precision disease networks, and its uses for predicting medical outcomes. Our methodology consists of building networks, one for each patient or case, that…

Quantitative Methods · Quantitative Biology 2019-11-01 J. Cabrera , D. Amaratunga , W. Kostis , J Kostis

Deep convolutional neural networks (CNNs) are the current state-of-the-art for digital analysis of histopathological images. The large size of whole-slide microscopy images (WSIs) requires advanced memory handling to read, display and…

Machine Learning · Computer Science 2020-11-13 André Pedersen , Marit Valla , Anna M. Bofin , Javier Pérez de Frutos , Ingerid Reinertsen , Erik Smistad

Cardiovascular disease (CVD) remains the foremost cause of mortality worldwide, underscoring the urgent need for intelligent and data-driven diagnostic tools. Traditional predictive models often struggle to generalize across heterogeneous…

Artificial Intelligence · Computer Science 2026-01-27 Rajan Das Gupta , Xiaobin Wu , Xun Liu , Jiaqi He

One major challenge in the medication of Parkinson's disease is that the severity of the disease, reflected in the patients' motor state, cannot be measured using accessible biomarkers. Therefore, we develop and examine a variety of…

Machine Learning · Computer Science 2019-04-26 Jann Goschenhofer , Franz MJ Pfister , Kamer Ali Yuksel , Bernd Bischl , Urban Fietzek , Janek Thomas

Deep neural networks (DNNs) have been widely applied to solve real-world regression problems. However, selecting optimal network structures remains a significant challenge. This study addresses this issue by linking neuron selection in DNNs…

Computation · Statistics 2025-09-30 Noah Yi-Ting Hung , Li-Hsiang Lin , Vince D. Calhoun

Handwritten Numeral recognition plays a vital role in postal automation services especially in countries like India where multiple languages and scripts are used Discrete Hidden Markov Model (HMM) and hybrid of Neural Network (NN) and HMM…

Neural and Evolutionary Computing · Computer Science 2012-03-20 Anshuman Sharma

A widely used test for the diagnosis of Parkinson's disease (PD) and Essential tremor (ET) is hand-drawn shapes,where the analysis is observationally performed by the examining neurologist. This method is subjective and is prone to bias…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Nabeel Seedat , Vered Aharonson , Ilana Schlesinger

This paper introduces a novel low-cost device prototype for the automatic diagnosis of diseases, utilizing inputted symptoms and personal background. The engineering goal is to solve the problem of limited healthcare access with a single…

Computers and Society · Computer Science 2019-01-07 Neil Deshmukh

To accurately analyze changes of anatomical structures in longitudinal imaging studies, consistent segmentation across multiple time-points is required. Existing solutions often involve independent registration and segmentation components.…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Bo Li , Wiro Niessen , Stefan Klein , Marius de Groot , Arfan Ikram , Meike Vernooij , Esther Bron

Background and Aim: Accurate classification of Magnetic Resonance Images (MRI) is essential to accurately predict Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) conversion. Meanwhile, deep learning has been successfully…

Computer Vision and Pattern Recognition · Computer Science 2021-09-03 Kshitiz Shrestha , Omar Hisham Alsadoon , Abeer Alsadoon , Tarik A. Rashid , Rasha S. Ali , P. W. C. Prasad , Oday D. Jerew

In the last decade, computer-aided early diagnostics of Alzheimer's Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research. Some recent studies have shown promising results in the AD…

Computer Vision and Pattern Recognition · Computer Science 2018-09-12 Alexander Khvostikov , Karim Aderghal , Andrey Krylov , Gwenaelle Catheline , Jenny Benois-Pineau