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One-dimensional NMR spectroscopy is one of the most widely used techniques for the characterization of organic compounds and natural products. For molecules with up to 36 non-hydrogen atoms, the number of possible structures has been…

Molecular function is largely determined by structure. Accurately aligning molecular structure with natural language is therefore essential for enabling large language models (LLMs) to reason about downstream chemical tasks. However, the…

Computation and Language · Computer Science 2026-05-11 Feiyang Cai , Guijuan He , Yi Hu , Jingjing Wang , Joshua Luo , Tianyu Zhu , Srikanth Pilla , Gang Li , Ling Liu , Feng Luo

We apply a number of atomic decomposition schemes across the standard QM7 dataset -- a small model set of organic molecules at equilibrium geometry -- to inspect the possible emergence of trends among contributions to atomization energies…

Chemical Physics · Physics 2023-04-19 Frederik Ø. Kjeldal , Janus J. Eriksen

Molecular-scale computation is crucial for smart materials and nanoscale devices, yet creating single-molecule systems capable of complex computations remains challenging. We present a theoretical framework for a single-molecule computer…

Statistical Mechanics · Physics 2024-10-01 Zhongmin Zhang , Zhiyue Lu

Supervised learning on molecules has incredible potential to be useful in chemistry, drug discovery, and materials science. Luckily, several promising and closely related neural network models invariant to molecular symmetries have already…

Machine Learning · Computer Science 2017-06-14 Justin Gilmer , Samuel S. Schoenholz , Patrick F. Riley , Oriol Vinyals , George E. Dahl

Unsupervised machine learning is widely used to mine large, unlabeled datasets to make data-driven discoveries in critical domains such as climate science, biomedicine, astronomy, chemistry, and more. However, despite its widespread…

Machine Learning · Computer Science 2025-06-06 Andersen Chang , Tiffany M. Tang , Tarek M. Zikry , Genevera I. Allen

In this paper, we address the problem of detecting small, dense, and overlapping objects, a major challenge in computer vision. Our focus is on reviewing proposed methods based on deep learning supervised approaches. We provide a detailed…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Oussama Messai , Abbass Zein-Eddine , Abdelouahid Bentamou , Mickael Picq , Nicolas Duquesne , Stéphane Puydarrieux , Yann Gavet

Molecular communication (MC) is a new communication engineering paradigm where molecules are employed as information carriers. MC systems are expected to enable new revolutionary applications such as sensing of target substances in…

Emerging Technologies · Computer Science 2018-12-14 Vahid Jamali , Arman Ahmadzadeh , Wayan Wicke , Adam Noel , Robert Schober

With the transformative technologies and the rapidly changing global R&D landscape, the multimedia and multimodal community is now faced with many new opportunities and uncertainties. With the open source dissemination platform and…

Natural language is expected to be a key medium for various human-machine interactions in the era of large language models. When it comes to the biochemistry field, a series of tasks around molecules (e.g., property prediction, molecule…

Computation and Language · Computer Science 2023-06-22 Zheni Zeng , Bangchen Yin , Shipeng Wang , Jiarui Liu , Cheng Yang , Haishen Yao , Xingzhi Sun , Maosong Sun , Guotong Xie , Zhiyuan Liu

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

Natural Language Processing (NLP) is widely used to supply summarization ability from long context to structured information. However, extracting structured knowledge from scientific text by NLP models remains a challenge because of its…

Computation and Language · Computer Science 2024-12-10 Tong Xie , Hanzhi Zhang , Shaozhou Wang , Yuwei Wan , Imran Razzak , Chunyu Kit , Wenjie Zhang , Bram Hoex

Microplastics (MPs) are ubiquitous pollutants with demonstrated potential to impact ecosystems and human health. Their microscopic size complicates detection, classification, and removal, especially in biological and environmental samples.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Paul-Tiberiu Miclea , Martin Sboron , Hardik Vaghasiya , Hoang Thinh Nguyen , Meet Gadara , Thomas Schmid

The World Wide Web (WWW) is a wonderful tool to provide users with documentation and tools that make the preparation and running of an experiment a little easier. We present a set of tools that allow one to estimate the activation of a…

Materials Science · Physics 2007-05-23 Th. Proffen , P. F. Peterson

Recent progress in self-supervised learning has resulted in models that are capable of extracting rich representations from image collections without requiring any explicit label supervision. However, to date the vast majority of these…

Computer Vision and Pattern Recognition · Computer Science 2021-06-10 Grant Van Horn , Elijah Cole , Sara Beery , Kimberly Wilber , Serge Belongie , Oisin Mac Aodha

Quantum entanglement and nonlocality are foundational to quantum technologies, driving quantum computation, communication, and cryptography innovations. To benchmark the capabilities of these quantum techniques, efficient detection and…

Quantum Physics · Physics 2024-12-03 Zhuo Chen , Fei Shi , Qi Zhao

Molecular science is governed by the dynamics of electrons, atomic nuclei, and their interaction with electromagnetic fields. A reliable physicochemical understanding of these processes is crucial for the design and synthesis of chemicals…

Quantum Physics · Physics 2022-03-21 Hongbin Liu , Guang Hao Low , Damian S. Steiger , Thomas Häner , Markus Reiher , Matthias Troyer

Specialized computational chemistry packages have permanently reshaped the landscape of chemical and materials science by providing tools to support and guide experimental efforts and for the prediction of atomistic and electronic…

Chemical Physics · Physics 2020-05-27 E. Aprà , E. J. Bylaska , W. A. de Jong , N. Govind , K. Kowalski , T. P. Straatsma , M. Valiev , H. J. J. van Dam , Y. Alexeev , J. Anchell , V. Anisimov , F. W. Aquino , R. Atta-Fynn , J. Autschbach , N. P. Bauman , J. C. Becca , D. E. Bernholdt , K. Bhaskaran-Nair , S. Bogatko , P. Borowski , J. Boschen , J. Brabec , A. Bruner , E. Cauët , Y. Chen , G. N. Chuev , C. J. Cramer , J. Daily , M. J. O. Deegan , T. H. Dunning , M. Dupuis , K. G. Dyall , G. I. Fann , S. A. Fischer , A. Fonari , H. Früuchtl , L. Gagliardi , J. Garza , N. Gawande , S. Ghosh , K. Glaesemann , A. W. Götz , J. Hammond , V. Helms , E. D. Hermes , K. Hirao , S. Hirata , M. Jacquelin , L. Jensen , B. G. Johnson , H. Jónsson , R. A. Kendall , M. Klemm , R. Kobayashi , V. Konkov , S. Krishnamoorthy , M. Krishnan , Z. Lin , R. D. Lins , R. J. Littlefield , A. J. Logsdail , K. Lopata , W. Ma , A. V. Marenich , J. Martin del Campo , D. Mejia-Rodriguez , J. E. Moore , J. M. Mullin , T. Nakajima , D. R. Nascimento , J. A. Nichols , P. J. Nichols , J. Nieplocha , A. Otero de la Roza , B. Palmer , A. Panyala , T. Pirojsirikul , B. Peng , R. Peverati , J. Pittner , L. Pollack , R. M. Richard , P. Sadayappan , G. C. Schatz , W. A. Shelton , D. W. Silverstein , D. M. A. Smith , T. A. Soares , D. Song , M. Swart , H. L. Taylor , G. S. Thomas , V. Tipparaju , D. G. Truhlar , K. Tsemekhman , T. Van Voorhis , Á. Vázquez-Mayagoitia , P. Verma , O. Villa , A. Vishnu , K. D. Vogiatzis , D. Wang , J. H. Weare , M. J. Williamson , T. L. Windus , K. Woliński , A. T. Wong , Q. Wu , C. Yang , Q. Yu , M. Zacharias , Z. Zhang , Y. Zhao , R. J. Harrison

Molecular biology explains function of molecules by their geometrical and electronical structures that are mainly determined by utilization of quantum effects in chemistry. However, further quantum effects are not thought to play any…

Quantum Physics · Physics 2011-12-30 Onur Pusuluk , Cemsinan Deliduman