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Related papers: Basic concepts for the Kermack and McKendrick mode…

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In this paper, we show how to modify a compartmental epidemic model, without changing the dimension, such that separable static heterogeneity is taken into account. The derivation is based on the Kermack-McKendrick renewal equation.

Populations and Evolution · Quantitative Biology 2022-11-24 Odo Diekmann , Hisashi Inaba

The aim of this short note is twofold. We formulate the general Kermack-McKendrick epidemic model incorporating static heterogeneity and show how it simplifies to a scalar Renewal Equation (RE) when separable mixing is assumed. A key…

Populations and Evolution · Quantitative Biology 2023-08-01 M. C. J. Bootsma , K. M. D. Chan , O. Diekmann , H. Inaba

This study introduces a novel epidemiological model that expands upon the Kermack-McKendrick model by incorporating the age of infection and reinfection. By including infection age, we can classify participants, which enables a more…

Populations and Evolution · Quantitative Biology 2025-12-08 Jiayi Li , Zhihua Liu , Zihan Wang

The suggestion by K.L. Cooke (1967) that infected individuals become infective if they are exposed often enough for a natural disease resistance to be overcome is built into a Kermack-McKendrick type epidemic model with infectivity age.…

Populations and Evolution · Quantitative Biology 2024-09-27 Joan Ponce , Horst R. Thieme

Since the start of the still ongoing COVID-19 pandemic, there have been many modeling efforts to assess several issues of importance to public health. In this work, we review the theory behind some important mathematical models that have…

Populations and Evolution · Quantitative Biology 2022-01-06 Fernando Saldaña , Jorge X Velasco-Hernández

During an epidemic, the infectiousness of infected individuals is known to depend on the time since the individual was infected, that is called the age of infection. Here we study the parameter identifiability of the Kermack-McKendrick…

Analysis of PDEs · Mathematics 2023-05-10 Jacques Demongeot , Quentin Griette , Yvon Maday , Pierre Magal

We propose an approach to model spatial heterogeneity in SIR-type models for the spread of epidemics via \emph{nonlocal aggregation terms}. More precisely, we first consider an SIR model with spatial movements driven by nonlocal aggregation…

Analysis of PDEs · Mathematics 2025-04-03 Marco Di Francesco , Fatemeh Ghaderi Zefreh

The primary tool for predicting infectious disease spread and intervention effectiveness is the mass action Susceptible-Infected-Recovered model of Kermack and McKendrick. Its usefulness derives largely from its conceptual and mathematical…

Populations and Evolution · Quantitative Biology 2015-09-03 Joel C. Miller , Anja C. Slim , Erik M. Volz

We investigate the global dynamics of a general Kermack-McKendrick-type epidemic model formulated in terms of a system of renewal equations. Specifically, we consider a renewal model for which both the force of infection and the infected…

Populations and Evolution · Quantitative Biology 2018-10-04 Michael T. Meehan , Daniel G. Cocks , Johannes Müller , Emma S. McBryde

We develop a general modelling framework for compartmental epidemiological systems structured by continuous variables which are linked to the levels of expression of compartment-specific traits. We start by formulating an individual-based…

Populations and Evolution · Quantitative Biology 2025-08-14 Emanuele Bernardi , Tommaso Lorenzi , Mattia Sensi , Andrea Tosin

A generalization of Kermack-McKendick model of epidemics to the case of inhomogeneous susceptibility of population is proposed. Some quantitative and qualitative features of epidemic process development in this situation are established.

Adaptation and Self-Organizing Systems · Physics 2008-11-20 E. Sh. Gutshabash , M. M. Brook

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

Methodology · Statistics 2014-11-14 Tom Britton , Federica Giardina

In this paper, an epidemic model with spatial dependence is studied and results regarding its stability and numerical approximation are presented. We consider a generalization of the original Kermack and McKendrick model in which the size…

Numerical Analysis · Mathematics 2022-04-05 Bálint Takács , Yiannis Hadjimichael

We study an infection-age structured epidemic model in which both the infectivity and the rate of loss of immunity depend on the time-since-infection. The model can be equivalently viewed as a nonlinear renewal equation for the incidence of…

Dynamical Systems · Mathematics 2025-11-13 Francesca Scarabel , Harry Coldwell , Tyler Cassidy

A compartment epidemic model for infectious disease spreading is investigated, where movement of individuals is governed by spatial diffusion. The model includes infection age of the infected individuals and assumes a logistic growth of the…

Analysis of PDEs · Mathematics 2023-06-28 Christoph Walker

The duration of the infectious period is a crucial determinant of the ability of an infectious disease to spread. We consider an epidemic model that is network based and non-Markovian, containing classic Kermack-McKendrick, pairwise,…

Populations and Evolution · Quantitative Biology 2018-05-25 Robert R. Wilkinson , Kieran J. Sharkey

This article presents a comprehensive study of the continuous McKendrick model, which serves as a foundational framework in population dynamics and epidemiology. The model is formulated through partial differential equations that describe…

Populations and Evolution · Quantitative Biology 2026-01-23 Dragos-Patru Covei

In the real world, many complex systems interact with other systems. In addition, the intra- or inter-systems for the spread of information about infectious diseases and the transmission of infectious diseases are often not random, but with…

Physics and Society · Physics 2017-08-23 Junbo Jia , Zhen Jin , Xinchu Fu

The basic and effective reproduction numbers are widely used metrics for characterizing the dynamics of infectious disease epidemics. However, the interpretation of these numbers is based on the assumption of homogeneous mixing and may not…

Populations and Evolution · Quantitative Biology 2026-03-24 Zahra Ghadiri , Jari Saramäki , Takayuki Hiraoka

We study a class of individual-based, fixed-population size epidemic models under general assumptions, e.g., heterogeneous contact rates encapsulating changes in behavior and/or enforcement of control measures. We show that the…

Probability · Mathematics 2023-07-04 Jean-Jil Duchamps , Félix Foutel-Rodier , Emmanuel Schertzer
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