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Ki67 is an important biomarker for breast cancer. Classification of positive and negative Ki67 cells in histology slides is a common approach to determine cancer proliferation status. However, there is a lack of generalizable and accurate…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Priya Lakshmi Narayanan , Shan E Ahmed Raza , Andrew Dodson , Barry Gusterson , Mitchell Dowsett , Yinyin Yuan

Liver cancer is one of the most prevalent and lethal forms of cancer, making early detection crucial for effective treatment. This paper introduces a novel approach for automated liver tumor segmentation in computed tomography (CT) images…

Machine Learning · Computer Science 2025-08-13 Nastaran Ghorbani , Bitasadat Jamshidi , Mohsen Rostamy-Malkhalifeh

We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Amir Gholami , Shashank Subramanian , Varun Shenoy , Naveen Himthani , Xiangyu Yue , Sicheng Zhao , Peter Jin , George Biros , Kurt Keutzer

Supervised deep learning has shown state-of-the-art performance for medical image segmentation across different applications, including histopathology and cancer research; however, the manual annotation of such data is extremely laborious.…

Pathology image segmentation is crucial in computational pathology for analyzing histological features relevant to cancer diagnosis and prognosis. However, current methods face major challenges in clinical applications due to limited…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zhixuan Chen , Junlin Hou , Liqi Lin , Yihui Wang , Yequan Bie , Xi Wang , Yanning Zhou , Ronald Cheong Kin Chan , Hao Chen

Cancer segmentation in whole-slide images is a fundamental step for viable tumour burden estimation, which is of great value for cancer assessment. However, factors like vague boundaries or small regions dissociated from viable tumour areas…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Yibao Sun , Giussepi Lopez , Yaqi Wang , Xingru Huang , Huiyu Zhou , Qianni Zhang

Despite the increasing use of deep learning in medical image segmentation, the limited availability of annotated training data remains a major challenge due to the time-consuming data acquisition and privacy regulations. In the context of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning

Breast magnetic resonance imaging is a critical tool for cancer detection and treatment planning, but its clinical utility is hindered by poor specificity, leading to high false-positive rates and unnecessary biopsies. This study introduces…

Artificial Intelligence · Computer Science 2025-10-07 Naomi Fridman , Anat Goldstein

Five different threshold segmentation based approaches have been reviewed and compared over here to extract the tumor from set of brain images. This research focuses on the analysis of image segmentation methods, a comparison of five…

Computer Vision and Pattern Recognition · Computer Science 2015-03-10 Muhammad Ali Qadar , Yan Zhaowen

Considering the increased workload in pathology laboratories today, automated tools such as artificial intelligence models can help pathologists with their tasks and ease the workload. In this paper, we are proposing a segmentation model…

Breast cancer is one of the most prevalent cancers worldwide and pathologists are closely involved in establishing a diagnosis. Tools to assist in making a diagnosis are required to manage the increasing workload. In this context,…

Brain tumor segmentation is an active research area due to the difficulty in delineating highly complex shaped and textured tumors as well as the failure of the commonly used U-Net architectures. The combination of different neural…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Lanhong Yao , Zheyuan Zhang , Ulas Bagci

Data augmentation refers to a group of techniques whose goal is to battle limited amount of available data to improve model generalization and push sample distribution toward the true distribution. While different augmentation strategies…

Quantitative Methods · Quantitative Biology 2020-06-03 Ruqian Hao , Khashayar Namdar , Lin Liu , Masoom A. Haider , Farzad Khalvati

Purpose: Accurate segmentation of prostate cancer on magnetic resonance (MR) images is crucial for planning image-guided interventions such as targeted biopsies, cryoablation, and radiotherapy. However, subtle and variable tumour…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Junqing Yang , Natasha Thorley , Ahmed Nadeem Abbasi , Shonit Punwani , Zion Tse , Yipeng Hu , Shaheer U. Saeed

Nuclei segmentation is a fundamental but challenging task in the quantitative analysis of histopathology images. Although fully-supervised deep learning-based methods have made significant progress, a large number of labeled images are…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Xinyi Yu , Guanbin Li , Wei Lou , Siqi Liu , Xiang Wan , Yan Chen , Haofeng Li

Magnetic resonance imaging (MRI) is an effective imaging modality for identifying and localizing breast lesions in women. Accurate and precise lesion segmentation using a computer-aided-diagnosis (CAD) system, is a crucial step in…

Computer Vision and Pattern Recognition · Computer Science 2017-12-15 Sulaiman Vesal , Andres Diaz-Pinto , Nishant Ravikumar , Stephan Ellmann , Amirabbas Davari , Andreas Maier

The high cure rate of cancer is inextricably linked to physicians' accuracy in diagnosis and treatment, therefore a model that can accomplish high-precision tumor segmentation has become a necessity in many applications of the medical…

Image and Video Processing · Electrical Eng. & Systems 2023-07-26 Zeqiu. Yu , Shuo. Han , Ziheng. Song

In the last decade, researchers working in the domain of computer vision and Artificial Intelligence (AI) have beefed up their efforts to come up with the automated framework that not only detects but also identifies stage of breast cancer.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-10 Shahid Munir Shah , Rizwan Ahmed Khan , Sheeraz Arif , Unaiza Sajid

Image segmentation is an important task in many medical applications. Methods based on convolutional neural networks attain state-of-the-art accuracy; however, they typically rely on supervised training with large labeled datasets. Labeling…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Amy Zhao , Guha Balakrishnan , Frédo Durand , John V. Guttag , Adrian V. Dalca