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Foundation models are experiencing a surge in popularity. The Segment Anything model (SAM) asserts an ability to segment a wide spectrum of objects but required supervised training at unprecedented scale. We compared SAM's performance…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Danielle Ferreira , Rima Arnaout

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Anwai Archit , Constantin Pape

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

This study investigates the potential of eye-tracking technology and the Segment Anything Model (SAM) to design a collaborative human-computer interaction system that automates medical image segmentation. We present the \textbf{GazeSAM}…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Bin Wang , Armstrong Aboah , Zheyuan Zhang , Ulas Bagci

Semantic segmentation requires dense pixel-level annotations, which are costly and time-consuming to acquire. To address this, we present SeSAM, a framework that uses a foundational segmentation model, i.e. Segment Anything Model (SAM),…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Anurag Das , Anna Kukleva , Xinting Hu , Yuki M. Asano , Bernt Schiele

We present ENSAM (Equivariant, Normalized, Segment Anything Model), a lightweight and promptable model for universal 3D medical image segmentation. ENSAM combines a SegResNet-based encoder with a prompt encoder and mask decoder in a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Elias Stenhede , Agnar Martin Bjørnstad , Arian Ranjbar

The modern deep learning field is a scale-centric one. Larger models have been shown to consistently perform better than smaller models of similar architecture. In many sub-domains of biomedical research, however, the model scaling is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Nicholas Kuang , Vanessa Scalon , Ji Yu

Due to the flexibility of prompting, foundation models have become the dominant force in the domains of natural language processing and image generation. With the recent introduction of the Segment Anything Model (SAM), the prompt-driven…

Image and Video Processing · Electrical Eng. & Systems 2023-08-14 Yichi Zhang , Rushi Jiao

Biomedical image analysis is fundamental for biomedical discovery in cell biology, pathology, radiology, and many other biomedical domains. Holistic image analysis comprises interdependent subtasks such as segmentation, detection, and…

Instance segmentation enables the analysis of spatial and temporal properties of cells in microscopy images by identifying the pixels belonging to each cell. However, progress is constrained by the scarcity of high-quality labeled…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Kaden Stillwagon , Alexandra Dunnum VandeLoo , Benjamin Magondu , Craig R. Forest

Accurate segmentation of brain tissues such as gray matter and white matter from magnetic resonance imaging is essential for studying brain anatomy, diagnosing neurological disorders, and monitoring disease progression. Traditional methods,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Chang Sun , Rui Shi , Tsukasa Koike , Tetsuro Sekine , Akio Morita , Tetsuya Sakai

Medical image and video segmentation is a critical task for precision medicine, which has witnessed considerable progress in developing task or modality-specific and generalist models for 2D images. However, there have been limited studies…

Image and Video Processing · Electrical Eng. & Systems 2025-04-07 Jun Ma , Zongxin Yang , Sumin Kim , Bihui Chen , Mohammed Baharoon , Adibvafa Fallahpour , Reza Asakereh , Hongwei Lyu , Bo Wang

Robust and accurate segmentation of scenes has become one core functionality in various visual recognition and navigation tasks. This has inspired the recent development of Segment Anything Model (SAM), a foundation model for general mask…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Aoran Xiao , Weihao Xuan , Heli Qi , Yun Xing , Naoto Yokoya , Shijian Lu

Although deep learning (DL) shows powerful potential in cell segmentation tasks, it suffers from poor generalization as DL-based methods originally simplified cell segmentation in detecting cell membrane boundary, lacking prominent cellular…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Fang Hu , Xuexue Sun , Ke Qing , Fenxi Xiao , Zhi Wang , Xiaolu Fan

Tongue segmentation serves as the primary step in automated TCM tongue diagnosis, which plays a significant role in the diagnostic results. Currently, numerous deep learning based methods have achieved promising results. However, when…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Shan Cao , Qunsheng Ruan , Linjian Ma

Cell segmentation is a major bottleneck in extracting quantitative single-cell information from microscopy data. The challenge is exasperated in the setting of microstructured environments. While deep learning approaches have proven useful…

Quantitative Methods · Quantitative Biology 2021-01-08 Tim Prangemeier , Christian Wildner , André O. Françani , Christoph Reich , Heinz Koeppl

Segmenting and recognizing diverse object parts is crucial in computer vision and robotics. Despite significant progress in object segmentation, part-level segmentation remains underexplored due to complex boundaries and scarce annotated…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Xinjian Wu , Ruisong Zhang , Jie Qin , Shijie Ma , Cheng-Lin Liu

The Segment Anything Model (SAM) is a powerful foundation model that introduced revolutionary advancements in natural image segmentation. However, its performance remains sub-optimal when delineating the intricate structure of biomedical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Xiangru Li , Yifei Zhang , Liang Zhao

Surgical segmentation is pivotal for scene understanding yet remains hindered by annotation scarcity and semantic inconsistency across diverse procedures. Existing approaches typically fine-tune natural foundation models (e.g., SAM) with…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 Qing Xu , Kun Yuan , Yuxiang Luo , Yuhao Zhai , Wenting Duan , Nassir Navab , Zhen Chen

With the development of Deep Neural Networks (DNNs), many efforts have been made to handle medical image segmentation. Traditional methods such as nnUNet train specific segmentation models on the individual datasets. Plenty of recent…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Xiaobao Wei , Jiajun Cao , Yizhu Jin , Ming Lu , Guangyu Wang , Shanghang Zhang
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