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Minimum flow decomposition (MFD) (the problem of finding a minimum set of paths that perfectly decomposes a flow) is a classical problem in Computer Science, and variants of it are powerful models in multiassembly problems in Bioinformatics…

Genomics · Quantitative Biology 2022-05-31 Fernando H. C. Dias , Lucia Williams , Brendan Mumey , Alexandru I. Tomescu

Minimum flow decomposition (MFD) -- the problem of finding a minimum set of weighted source-to-sink paths that perfectly decomposes a flow -- is a classical problem in Computer Science, and variants of it are powerful models in different…

Data Structures and Algorithms · Computer Science 2023-01-18 Fernando H. C. Dias , Lucia Williams , Brendan Mumey , Alexandru I. Tomescu

Minimum flow decomposition (MFD) is the strongly NP-hard problem of finding a smallest set of integer weighted $s$-$t$ paths in an $s$-$t$ DAG $G$ whose weighted sum is equal to a given flow $f$ on $G$. Despite its many practical…

Data Structures and Algorithms · Computer Science 2025-12-01 Andreas Grigorjew , Wanchote Jiamjitrak , Brendan Mumey , Alexandru I. Tomescu

Many important problems in Bioinformatics (e.g., assembly or multi-assembly) admit multiple solutions, while the final objective is to report only one. A common approach to deal with this uncertainty is finding safe partial solutions (e.g.,…

Data Structures and Algorithms · Computer Science 2023-02-01 Fernando H. C. Dias , Manuel Caceres , Lucia Williams , Brendan Mumey , Alexandru I. Tomescu

Minimum flow decomposition (MFD) is the NP-hard problem of finding a smallest decomposition of a network flow/circulation $X$ on a directed graph $G$ into weighted source-to-sink paths whose superposition equals $X$. We show that, for…

Data Structures and Algorithms · Computer Science 2023-05-11 Manuel Cáceres , Massimo Cairo , Andreas Grigorjew , Shahbaz Khan , Brendan Mumey , Romeo Rizzi , Alexandru I. Tomescu , Lucia Williams

In this paper, we generalize the minimum flow decomposition problem (MFD) to incorporate uncertain edge capacities and tackle it from the perspective of robust optimization. In the classical flow decomposition problem, a network flow is…

Optimization and Control · Mathematics 2025-10-17 Moritz Stinzendörfer , Philine Schiewe , Fabricio Oliveira

Decomposing a flow on a Directed Acyclic Graph (DAG) into a weighted sum of a small number of paths is an essential task in operations research and bioinformatics. This problem, referred to as Sparse Flow Decomposition (SFD), has gained…

Optimization and Control · Mathematics 2025-07-22 Mathieu Besançon

The Flow Decomposition problem, which asks for the smallest set of weighted paths that "covers" a flow on a DAG, has recently been used as an important computational step in transcript assembly. We prove the problem is in FPT when…

Data Structures and Algorithms · Computer Science 2017-08-31 Kyle Kloster , Philipp Kuinke , Michael P. O'Brien , Felix Reidl , Fernando Sánchez Villaamil , Blair D. Sullivan , Andrew van der Poel

Densest Subgraph Problem (DSP) is an important primitive problem with a wide range of applications, including fraud detection, community detection and DNA motif discovery. Edge-based density is one of the most common metrics in DSP.…

Databases · Computer Science 2023-10-31 Yugao Zhu , Shenghua Liu , Wenjie Feng , Xueqi Cheng

Solving the Multi-Agent Path Finding (MAPF) problem optimally is known to be NP-Hard for both make-span and total arrival time minimization. While many algorithms have been developed to solve MAPF problems, there is no dominating optimal…

Multiagent Systems · Computer Science 2024-12-20 Jingyao Ren , Vikraman Sathiyanarayanan , Eric Ewing , Baskin Senbaslar , Nora Ayanian

Multi-assembly methods rely at their core on a flow decomposition problem, namely, decomposing a weighted graph into weighted paths or walks. However, most results over the past decade have focused on decompositions over directed acyclic…

Data Structures and Algorithms · Computer Science 2025-11-25 Francisco Sena , Alexandru I. Tomescu

In this work, we consider compressible single-phase flow problems in a porous media containing a fracture. In the latter, a non-linear pressure-velocity relation is prescribed. Using a non-overlapping domain decomposition procedure, we…

Determining the maximum demand a water distribution network can satisfy is crucial for ensuring reliable supply and planning network expansion. This problem, typically formulated as a mixed-integer nonlinear program (MINLP), is…

Optimization and Control · Mathematics 2026-01-13 Sai Krishna Kanth Hari , Russell Bent

In this paper we provide new randomized algorithms with improved runtimes for solving linear programs with two-sided constraints. In the special case of the minimum cost flow problem on $n$-vertex $m$-edge graphs with integer…

Data Structures and Algorithms · Computer Science 2021-08-24 Jan van den Brand , Yin Tat Lee , Yang P. Liu , Thatchaphol Saranurak , Aaron Sidford , Zhao Song , Di Wang

We formalize Multi-Agent Path Finding with Deadlines (MAPF-DL). The objective is to maximize the number of agents that can reach their given goal vertices from their given start vertices within the deadline, without colliding with each…

Artificial Intelligence · Computer Science 2018-06-13 Hang Ma , Glenn Wagner , Ariel Felner , Jiaoyang Li , T. K. Satish Kumar , Sven Koenig

Approximate linear programming (ALP) is an efficient approach to solving large factored Markov decision processes (MDPs). The main idea of the method is to approximate the optimal value function by a set of basis functions and optimize…

Artificial Intelligence · Computer Science 2012-06-18 Branislav Kveton , Milos Hauskrecht

Embedding deep neural networks (NNs) into mixed-integer programs (MIPs) is attractive for decision making with learned constraints, yet state-of-the-art monolithic linearisations blow up in size and quickly become intractable. In this…

Optimization and Control · Mathematics 2025-11-13 Shuli Zeng , Sijia Zhang , Feng Wu , Shaojie Tang , Xiang-Yang Li

Dynamic mode decomposition (DMD) represents an effective means for capturing the essential features of numerically or experimentally generated flow fields. In order to achieve a desirable tradeoff between the quality of approximation and…

Fluid Dynamics · Physics 2014-12-11 Mihailo R. Jovanović , Peter J. Schmid , Joseph W. Nichols

In numerical linear algebra, considerable effort has been devoted to obtaining faster algorithms for linear systems whose underlying matrices exhibit structural properties. A prominent success story is the method of generalized nested…

Data Structures and Algorithms · Computer Science 2023-10-26 Sally Dong , Gramoz Goranci , Lawrence Li , Sushant Sachdeva , Guanghao Ye

We formalize the problem of multi-agent path finding with deadlines (MAPF-DL). The objective is to maximize the number of agents that can reach their given goal vertices from their given start vertices within a given deadline, without…

Artificial Intelligence · Computer Science 2018-05-15 Hang Ma , Glenn Wagner , Ariel Felner , Jiaoyang Li , T. K. Satish Kumar , Sven Koenig
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