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Resting-state functional magnetic resonance imaging (rs-fMRI) offers a non-invasive approach to examining abnormal brain connectivity associated with brain disorders. Graph neural network (GNN) gains popularity in fMRI representation…

Quantitative Methods · Quantitative Biology 2023-08-22 Junhao Zhang , Qianqian Wang , Xiaochuan Wang , Lishan Qiao , Mingxia Liu

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Resting-state functional magnetic resonance imaging (rs-fMRI)-derived functional connectivity patterns have been extensively utilized to delineate global functional organization of the human brain in health, development, and…

Quantitative Methods · Quantitative Biology 2020-10-02 Li Xiao , Biao Cai , Gang Qu , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Resting-state functional MRI (rs-fMRI) is widely used to noninvasively study human brain networks. Network functional connectivity is often estimated by calculating the timeseries correlation between blood-oxygen-level dependent (BOLD)…

Quantitative Methods · Quantitative Biology 2017-01-25 Nan Xu , R. Nathan Spreng , Peter C. Doerschuk

Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

Predicting cognition from neuroimaging data in healthy individuals offers insights into the neural mechanisms underlying cognitive abilities, with potential applications in precision medicine and early detection of neurological and…

Machine Learning · Computer Science 2025-07-29 Jagruti Patel , Mikkel Schöttner , Thomas A. W. Bolton , Patric Hagmann

Due to the spontaneous nature of resting-state fMRI (rs-fMRI) signals, cross-subject comparison and therefore, group studies of rs-fMRI are challenging. Most existing group comparison methods use features extracted from the fMRI time…

Signal Processing · Electrical Eng. & Systems 2020-12-15 Anand A. Joshi , Soyoung Choi , Haleh Akrami , Richard M. Leahy

Evaluating similarity between graphs is of major importance in several computer vision and pattern recognition problems, where graph representations are often used to model objects or interactions between elements. The choice of a distance…

Computer Vision and Pattern Recognition · Computer Science 2017-06-15 Sofia Ira Ktena , Sarah Parisot , Enzo Ferrante , Martin Rajchl , Matthew Lee , Ben Glocker , Daniel Rueckert

Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

Resting-state functional MRI (rs-fMRI) is a rich imaging modality that captures spontaneous brain activity patterns, revealing clues about the connectomic organization of the human brain. While many rs-fMRI studies have focused on static…

Machine Learning · Computer Science 2019-08-20 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert R. Sabuncu

Psychiatric research has been hampered by an explanatory gap between psychiatric symptoms and their neural underpinnings, which has resulted in poor treatment outcomes. This situation has prompted us to shift from symptom-based diagnosis to…

Resting-state functional MRI (rs-fMRI) in functional neuroimaging techniques have improved in brain disorders, dysfunction studies via mapping the topology of the brain connections, i.e. connectopic mapping. Since, there are the slight…

Image and Video Processing · Electrical Eng. & Systems 2019-07-18 Jalal Mirakhorli , Hamidreza Amindavar , Mojgan Mirakhorli

The Blood-Oxygen-Level-Dependent (BOLD) signal of resting-state fMRI (rs-fMRI) records the temporal dynamics of intrinsic functional networks in the brain. However, existing deep learning methods applied to rs-fMRI either neglect the…

Machine Learning · Computer Science 2021-06-30 Soham Gadgil , Qingyu Zhao , Adolf Pfefferbaum , Edith V. Sullivan , Ehsan Adeli , Kilian M. Pohl

Contrastive self-supervised learning has recently benefited fMRI classification with inductive biases. Its weak label reliance prevents overfitting on small medical datasets and tackles the high intraclass variances. Nonetheless, existing…

Machine Learning · Computer Science 2022-07-19 Xuesong Wang , Lina Yao , Islem Rekik , Yu Zhang

We propose a matrix factorization technique that decomposes the resting state fMRI (rs-fMRI) correlation matrices for a patient population into a sparse set of representative subnetworks, as modeled by rank one outer products. The…

Signal Processing · Electrical Eng. & Systems 2018-07-26 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

Functional brain connectivity, as revealed through distant correlations in the signals measured by functional Magnetic Resonance Imaging (fMRI), is a promising source of biomarkers of brain pathologies. However, establishing and using…

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

Neurons and Cognition · Quantitative Biology 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Structural magnetic resonance imaging (sMRI) has shown great clinical value and has been widely used in deep learning (DL) based computer-aided brain disease diagnosis. Previous approaches focused on local shapes and textures in sMRI that…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Gongshu Wang , Ning Jiang , Yunxiao Ma , Tiantian Liu , Duanduan Chen , Jinglong Wu , Guoqi Li , Dong Liang , Tianyi Yan

Functional magnetic resonance imaging (fMRI) data have become increasingly available and are useful for describing functional connectivity (FC), the relatedness of neuronal activity in regions of the brain. This FC of the brain provides…

Machine Learning · Statistics 2020-10-14 Andrew DiLernia , Karina Quevedo , Jazmin Camchong , Kelvin Lim , Wei Pan , Lin Zhang

Resting-state functional magnetic resonance imaging (rs-fMRI) can reflect spontaneous neural activities in brain and is widely used for brain disorder analysis.Previous studies propose to extract fMRI representations through diverse…

Quantitative Methods · Quantitative Biology 2023-06-27 Qianqian Wang , Wei Wang , Yuqi Fang , P. -T. Yap , Hongtu Zhu , Hong-Jun Li , Lishan Qiao , Mingxia Liu
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