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Foundation models for medical imaging are typically pretrained on increasingly large datasets, following a "scale-at-all-costs" paradigm. However, this strategy faces two critical challenges: large-scale medical datasets often contain…

Advances in markerless motion capture are expanding access to biomechanical movement analysis, making it feasible to obtain high-quality movement data from outpatient clinics, inpatient hospitals, therapy, and even home. Expanding access to…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Ruize Yang , Ann Kennedy , R. James Cotton

Transfer learning from supervised ImageNet models has been frequently used in medical image analysis. Yet, no large-scale evaluation has been conducted to benchmark the efficacy of newly-developed pre-training techniques for medical image…

Computer Vision and Pattern Recognition · Computer Science 2021-08-16 Mohammad Reza Hosseinzadeh Taher , Fatemeh Haghighi , Ruibin Feng , Michael B. Gotway , Jianming Liang

Despite the impressive advancements achieved using deep-learning for functional brain activity analysis, the heterogeneity of functional patterns and scarcity of imaging data still pose challenges in tasks such as prediction of future onset…

Image and Video Processing · Electrical Eng. & Systems 2023-12-25 Wenhui Cui , Haleh Akrami , Ganning Zhao , Anand A. Joshi , Richard M. Leahy

Federated learning enables collaborative model training across geographically distributed medical centers while preserving data privacy. However, domain shifts and heterogeneity in data often lead to a degradation in model performance.…

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

Foundation models have become a promising paradigm for advancing medical image analysis, particularly for segmentation tasks where downstream applications often emerge sequentially. Existing fine-tuning strategies, however, remain limited:…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Yiwen Ye , Yicheng Wu , Xiangde Luo , He Zhang , Ziyang Chen , Ting Dang , Yanning Zhang , Yong Xia

In this paper, we introduce a new vision-language pre-trained model -- ImageBERT -- for image-text joint embedding. Our model is a Transformer-based model, which takes different modalities as input and models the relationship between them.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Di Qi , Lin Su , Jia Song , Edward Cui , Taroon Bharti , Arun Sacheti

While emerging 3D medical foundation models are envisioned as versatile tools with offer general-purpose capabilities, their validation remains largely confined to regional and structural imaging, leaving a significant modality discrepancy…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yichi Zhang , Feiyang Xiao , Le Xue , Wenbo Zhang , Gang Feng , Chenguang Zheng , Yuan Qi , Yuan Cheng , Zixin Hu

Deep Learning (DL) requires a large amount of training data to provide quality outcomes. However, the field of medical imaging suffers from the lack of sufficient data for properly training DL models because medical images require manual…

Computer Vision and Pattern Recognition · Computer Science 2021-10-14 Laith Alzubaidi , J. Santamaría , Mohamed Manoufali , Beadaa Mohammed , Mohammed A. Fadhel , Jinglan Zhang , Ali H. Al-Timemy , Omran Al-Shamma , Ye Duan

This paper introduces the DeepATLAS foundational model for localization tasks in the domain of high-dimensional biomedical data. Upon convergence of the proposed self-supervised objective, a pretrained model maps an input to an…

Computer Vision and Pattern Recognition · Computer Science 2024-02-16 Peter D. Chang

Foundation models, pre-trained on massive datasets, have achieved unprecedented generalizability. However, is it truly necessary to involve such vast amounts of data in pre-training, consuming extensive computational resources? This paper…

Machine Learning · Computer Science 2024-08-19 Wenxuan Yang , Weimin Tan , Yuqi Sun , Bo Yan

Current volumetric biomedical foundation models struggle to generalize as public 3D datasets are small and do not cover the broad diversity of medical procedures, conditions, anatomical regions, and imaging protocols. We address this by…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Neel Dey , Benjamin Billot , Hallee E. Wong , Clinton J. Wang , Mengwei Ren , P. Ellen Grant , Adrian V. Dalca , Polina Golland

Deep learning-based models, when trained in a fully-supervised manner, can be effective in performing complex image analysis tasks, although contingent upon the availability of large labeled datasets. Especially in the medical imaging…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Ayaan Haque , Abdullah-Al-Zubaer Imran , Adam Wang , Demetri Terzopoulos

Object detection, segmentation and classification are three common tasks in medical image analysis. Multi-task deep learning (MTL) tackles these three tasks jointly, which provides several advantages saving computing time and resources and…

Computer Vision and Pattern Recognition · Computer Science 2019-06-06 Fei Gao , Hyunsoo Yoon , Teresa Wu , Xianghua Chu

Medical imaging tasks are very challenging due to the lack of publicly available labeled datasets. Hence, it is difficult to achieve high performance with existing deep-learning models as they require a massive labeled dataset to be trained…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Anubhav Gupta , Islam Osman , Mohamed S. Shehata , John W. Braun

Radiological analysis increasingly benefits from pretrained visual representations that can support heterogeneous downstream tasks across imaging modalities. In this work, we introduce OmniRad, a self-supervised radiological foundation…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Luca Zedda , Andrea Loddo , Cecilia Di Ruberto

Current multimodal and multitask foundation models like 4M or UnifiedIO show promising results, but in practice their out-of-the-box abilities to accept diverse inputs and perform diverse tasks are limited by the (usually rather small)…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Roman Bachmann , Oğuzhan Fatih Kar , David Mizrahi , Ali Garjani , Mingfei Gao , David Griffiths , Jiaming Hu , Afshin Dehghan , Amir Zamir

Foundation models are multi-dataset and multi-task machine learning methods that once pre-trained can be fine-tuned for a large variety of downstream applications. The successful development of such general-purpose models for physics data…

High Energy Physics - Phenomenology · Physics 2024-09-10 Joschka Birk , Anna Hallin , Gregor Kasieczka