English
Related papers

Related papers: Do Physicians Know How to Prompt? The Need for Aut…

200 papers

LLM performance is highly sensitive to prompt design, yet whether automatic prompt optimization can replace expert prompt engineering in linguistic tasks remains unexplored. We present the first systematic comparison of hand-crafted…

Computation and Language · Computer Science 2026-05-06 Marina Sánchez-Torrón , Daria Akselrod , Jason Rauchwerk

Large Language Models (LLMs) can perform various natural language processing tasks with suitable instruction prompts. However, designing effective prompts manually is challenging and time-consuming. Existing methods for automatic prompt…

Computation and Language · Computer Science 2024-04-04 Viet-Tung Do , Van-Khanh Hoang , Duy-Hung Nguyen , Shahab Sabahi , Jeff Yang , Hajime Hotta , Minh-Tien Nguyen , Hung Le

Prompt optimization is a practical and widely applicable alternative to fine tuning for improving large language model performance. Yet many existing methods evaluate candidate prompts by sampling full outputs, often coupled with self…

Computation and Language · Computer Science 2025-09-19 Chenzhuo Zhao , Ziqian Liu , Xinda Wang , Junting Lu , Chaoyi Ruan

This study explores a novel approach to enhance the performance of Large Language Models (LLMs) through the optimization of input data within prompts. While previous research has primarily focused on refining instruction components and…

Machine Learning · Computer Science 2025-02-18 Sam Lin , Wenyue Hua , Lingyao Li , Zhenting Wang , Yongfeng Zhang

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Artificial Intelligence · Computer Science 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

Large language models (LLMs) have shown remarkable capabilities in Natural Language Processing (NLP), especially in domains where labeled data is scarce or expensive, such as clinical domain. However, to unlock the clinical knowledge hidden…

Computation and Language · Computer Science 2023-09-18 Sonish Sivarajkumar , Mark Kelley , Alyssa Samolyk-Mazzanti , Shyam Visweswaran , Yanshan Wang

Prompt engineering has demonstrated remarkable success in enhancing the performance of large language models (LLMs) across diverse tasks. However, most existing prompt optimization methods only focus on the task-level performance,…

Artificial Intelligence · Computer Science 2025-06-02 Yilun Kong , Hangyu Mao , Qi Zhao , Bin Zhang , Jingqing Ruan , Li Shen , Yongzhe Chang , Xueqian Wang , Rui Zhao , Dacheng Tao

Large Language Models (LLMs) have achieved remarkable success across diverse tasks, largely driven by well-designed prompts. However, crafting and selecting such prompts often requires considerable human effort, significantly limiting its…

Computation and Language · Computer Science 2025-03-20 Dengyun Peng , Yuhang Zhou , Qiguang Chen , Jinhao Liu , Jingjing Chen , Libo Qin

Numerous recent works aim to enhance the efficacy of Large Language Models (LLMs) through strategic prompting. In particular, the Optimization by PROmpting (OPRO) approach provides state-of-the-art performance by leveraging LLMs as…

Computation and Language · Computer Science 2024-07-22 Tuo Zhang , Jinyue Yuan , Salman Avestimehr

Prompt engineering is crucial for achieving reliable and effective outputs from large language models (LLMs), but its design requires specialized knowledge of prompting techniques and a deep understanding of target tasks. To address this…

Computation and Language · Computer Science 2025-10-22 Yohei Ikenoue , Hitomi Tashiro , Shigeru Kuroyanagi

Large language models (LLMs) are highly sensitive to prompts, but most automatic prompt optimization (APO) methods assume access to ground-truth references (e.g., labeled validation data) that are costly to obtain. We propose the Prompt…

Computation and Language · Computer Science 2026-04-10 Yuanchen Wu , Saurabh Verma , Justin Lee , Fangzhou Xiong , Poppy Zhang , Amel Awadelkarim , Xu Chen , Yubai Yuan , Shawndra Hill

Large language models (LLMs) have achieved great success across diverse tasks, and fine-tuning is sometimes needed to further enhance generation quality. Most existing methods rely on human supervision or parameter retraining, both of which…

Computation and Language · Computer Science 2025-05-27 Zhen-Yu Zhang , Jiandong Zhang , Huaxiu Yao , Gang Niu , Masashi Sugiyama

Prompt optimization is essential for enhancing the performance of Large Language Models (LLMs) in a range of Natural Language Processing (NLP) tasks, particularly in scenarios of few-shot learning where training examples are incorporated…

Computation and Language · Computer Science 2024-08-15 Dai Do , Quan Tran , Svetha Venkatesh , Hung Le

Prompt engineering significantly influences the reliability and clinical utility of Large Language Models (LLMs) in medical applications. Current optimization approaches inadequately address domain-specific medical knowledge and safety…

Computation and Language · Computer Science 2025-08-26 Yinda Chen , Yangfan He , Jing Yang , Dapeng Zhang , Zhenlong Yuan , Muhammad Attique Khan , Jamel Baili , Por Lip Yee

Linguistic expressions of emotions such as depression, anxiety, and trauma-related states are pervasive in clinical notes, counseling dialogues, and online mental health communities, and accurate recognition of these emotions is essential…

Artificial Intelligence · Computer Science 2026-01-21 Jian Zhang , Zhangqi Wang , Zhiyuan Wang , Weiping Fu , Yu He , Haiping Zhu , Qika Lin , Jun Liu

Large language models (LLMs) typically operate in a question-answering paradigm, where the quality of the input prompt critically affects the response. Automated Prompt Optimization (APO) aims to overcome the cognitive biases of manually…

Computation and Language · Computer Science 2025-11-13 Jian Zhang , Zhangqi Wang , Haiping Zhu , Kangda Cheng , Kai He , Bo Li , Qika Lin , Jun Liu , Erik Cambria

In the past decade a surge in the amount of electronic health record (EHR) data in the United States, attributed to a favorable policy environment created by the Health Information Technology for Economic and Clinical Health (HITECH) Act of…

Computation and Language · Computer Science 2025-12-08 Ivan Makohon , Mohamad Najafi , Jian Wu , Mathias Brochhausen , Yaohang Li

Prompt engineering has emerged as a critical component in optimizing large language models (LLMs) for domain-specific tasks. However, the role of prompt specificity, especially in domains like STEM (physics, chemistry, biology, computer…

Computation and Language · Computer Science 2025-05-26 Dimitri Schreiter

Prompt engineering is effective but labor-intensive, motivating automated optimization methods. Existing methods typically require labeled datasets, which are often unavailable, and produce verbose, repetitive prompts. We introduce PrefPO,…

Computation and Language · Computer Science 2026-03-26 Rahul Singhal , Pradyumna Tambwekar , Karime Maamari

The performance of Large Language Models (LLMs) relies heavily on the quality of prompts, which are often manually engineered and task-specific, making them costly and non-scalable. We propose a novel approach, Supervisory Prompt Training…

Computation and Language · Computer Science 2024-03-28 Jean Ghislain Billa , Min Oh , Liang Du