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Purpose: To explore best-practice approaches for generating synthetic chest X-ray images and augmenting medical imaging datasets to optimize the performance of deep learning models in downstream tasks like classification and segmentation.…

Supervised training of an automated medical image analysis system often requires a large amount of expert annotations that are hard to collect. Moreover, the proportions of data available across different classes may be highly imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yuan Xue , Jiarong Ye , Rodney Long , Sameer Antani , Zhiyun Xue , Xiaolei Huang

Access to high-quality datasets in the medical industry limits machine learning model performance. To address this issue, we propose a Denoising Diffusion Probabilistic Model (DDPM) combined with a UNet architecture for X-ray image…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Praveen Mahaulpatha , Thulana Abeywardane , Tomson George

Federated learning enables collaborative training of deep learning models across institutions without sharing sensitive patient data. However, its performance is often limited by small datasets and non-independent, identically distributed…

Image and Video Processing · Electrical Eng. & Systems 2026-04-17 Hongyi Pan , Ziliang Hong , Gorkem Durak , Ziyue Xu , Ulas Bagci

Since the beginning of the COVID-19 pandemic, researchers have developed deep learning models to classify COVID-19 induced pneumonia. As with many medical imaging tasks, the quality and quantity of the available data is often limited. In…

Image and Video Processing · Electrical Eng. & Systems 2021-12-15 Daniel Schaudt , Christopher Kloth , Christian Spaete , Andreas Hinteregger , Meinrad Beer , Reinhold von Schwerin

The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Kathrin Khadra , Utku Türkbey

Deep learning-based automated diagnosis of lung cancer has emerged as a crucial advancement that enables healthcare professionals to detect and initiate treatment earlier. However, these models require extensive training datasets with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Aryan Goyal , Ashish Mittal , Pranav Rao , Manoj Tadepalli , Preetham Putha

Recent advances in computer vision have shown promising results in image generation. Diffusion probabilistic models in particular have generated realistic images from textual input, as demonstrated by DALL-E 2, Imagen and Stable Diffusion.…

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Luke W. Sagers , James A. Diao , Luke Melas-Kyriazi , Matthew Groh , Pranav Rajpurkar , Adewole S. Adamson , Veronica Rotemberg , Roxana Daneshjou , Arjun K. Manrai

Developing new methods for the automated analysis of clinical fetal and neonatal MRI data is limited by the scarcity of annotated pathological datasets and privacy concerns that often restrict data sharing, hindering the effectiveness of…

Deep learning techniques for anatomical landmark localization (ALL) have shown great success, but their reliance on large annotated datasets remains a problem due to the tedious and costly nature of medical data acquisition and annotation.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Arnela Hadzic , Lea Bogensperger , Simon Johannes Joham , Martin Urschler

The rapid advancement of Artificial Intelligence (AI) in biomedical imaging and radiotherapy is hindered by the limited availability of large imaging data repositories. With recent research and improvements in denoising diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Rowan Bradbury , Katherine A. Vallis , Bartlomiej W. Papiez

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Generative image models have achieved remarkable progress in both natural and medical imaging. In the medical context, these techniques offer a potential solution to data scarcity-especially for low-prevalence anomalies that impair the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Gregory Schuit , Denis Parra , Cecilia Besa

Machine learning in neurosurgery is limited by challenges in assembling large, high-quality imaging datasets. Synthetic data offers a scalable, privacy-preserving solution. We evaluated the feasibility of generating realistic lateral…

Medical image analysis suffers from a lack of labeled data due to several challenges including patient privacy and lack of experts. Although some AI models only perform well with large amounts of data, we will move to data augmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Khadija Rais , Mohamed Amroune , Mohamed Yassine Haouam , Abdelmadjid Benmachiche

We trained a classifier with synthetic chest X-ray (CXR) images generated by Nano Banana, the latest AI model for image generation and editing, released by Google. When directly applied to real-world CXRs having only been trained with…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Jiachuan Peng , Kyle Lam , Jianing Qiu

Small datasets are common in health research. However, the generalization performance of machine learning models is suboptimal when the training datasets are small. To address this, data augmentation is one solution. Augmentation increases…

Synthesizing realistic medical images provides a feasible solution to the shortage of training data in deep learning based medical image recognition systems. However, the quality control of synthetic images for data augmentation purposes is…

Computer Vision and Pattern Recognition · Computer Science 2020-08-27 Jiarong Ye , Yuan Xue , L. Rodney Long , Sameer Antani , Zhiyun Xue , Keith Cheng , Xiaolei Huang

Acquiring large quantities of data and annotations is known to be effective for developing high-performing deep learning models, but is difficult and expensive to do in the healthcare context. Adding synthetic training data using generative…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Menghan Yu , Sourabh Kulhare , Courosh Mehanian , Charles B Delahunt , Daniel E Shea , Zohreh Laverriere , Ishan Shah , Matthew P Horning
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