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This study proposes an unsupervised sequence-to-sequence learning approach that automatically assesses the motion-induced reliability degradation of the cardiac volume signal (CVS) in multi-channel electrical impedance-based hemodynamic…

Signal Processing · Electrical Eng. & Systems 2023-05-18 Chang Min Hyun , Tae-Geun Kim , Kyounghun Lee

Non-coplanar Intensity-Modulated Radiation Therapy (IMRT) goes a step further by orienting the gantry carrying the radiation beam and the patient couch in a non-coplanar manner to accurately target the cancer region and better avoid…

Medical Physics · Physics 2023-05-16 Fang Guo , Franklin Okoli , Ulrike Schick , Dimitris Visvikis , Antoine Valeri , Julien Bert

Objectives We aimed to evaluate the diagnostic performance of deep learning (DL)-based radiomics models for the noninvasive prediction of isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion status in glioma patients using MRI…

Quantitative Methods · Quantitative Biology 2025-08-19 Somayeh Farahani , Marjaneh Hejazi , Mehnaz Tabassum , Antonio Di Ieva , Neda Mahdavifar , Sidong Liu

Medical image segmentation is vital for clinical diagnosis, yet current deep learning methods often demand extensive expert effort, i.e., either through annotating large training datasets or providing prompts at inference time for each new…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Xingjian Li , Qifeng Wu , Adithya S. Ubaradka , Yiran Ding , Colleen Que , Runmin Jiang , Jianhua Xing , Tianyang Wang , Min Xu

Diagnosis of breast carcinomas has so far been limited to the morphological interpretation of epithelial cells and the assessment of epithelial tissue architecture. Consequently, most of the automated systems have focused on characterizing…

Computer Vision and Pattern Recognition · Computer Science 2017-02-21 Babak Ehteshami Bejnordi , Jimmy Linz , Ben Glass , Maeve Mullooly , Gretchen L Gierach , Mark E Sherman , Nico Karssemeijer , Jeroen van der Laak , Andrew H Beck

Pretraining with large-scale 3D volumes has a potential for improving the segmentation performance on a target medical image dataset where the training images and annotations are limited. Due to the high cost of acquiring pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Guotai Wang , Jianghao Wu , Xiangde Luo , Xinglong Liu , Kang Li , Shaoting Zhang

Accurate, real-time monitoring of tissue ischemia is crucial to understand tissue health and guide surgery. Spectral imaging shows great potential for contactless and intraoperative monitoring of tissue oxygenation. Due to the difficulty of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Jens De Winne , Siri Willems , Siri Luthman , Danilo Babin , Hiep Luong , Wim Ceelen

Effective surgical planning for breast cancer hinges on accurately predicting pathological complete response (pCR) to neoadjuvant chemotherapy (NAC). Diffusion-weighted MRI (DWI) and machine learning offer a non-invasive approach for early…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Shir Nitzan , Maya Gilad , Moti Freiman

For several cancer patients, operative resection with curative intent can end up in early recurrence of the cancer. Current limitations in peri-operative cancer staging and especially intra-operative misidentification of visible metastases…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Thomas Schnelldorfer , Janil Castro , Atoussa Goldar-Najafi , Liping Liu

Manual counting of mitotic tumor cells in tissue sections constitutes one of the strongest prognostic markers for breast cancer. This procedure, however, is time-consuming and error-prone. We developed a method to automatically detect…

Accurate analysis of the fibrosis stage plays very important roles in follow-up of patients with chronic hepatitis B infection. In this paper, a deep learning framework is presented for automatically liver fibrosis prediction. On contrary…

Image and Video Processing · Electrical Eng. & Systems 2020-09-11 Jiali Liu , Wenxuan Wang , Tianyao Guan , Ningbo Zhao , Xiaoguang Han , Zhen Li

Cancer detection and classification from gigapixel whole slide images of stained tissue specimens has recently experienced enormous progress in computational histopathology. The limitation of available pixel-wise annotated scans shifted the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Mehdi Naouar , Gabriel Kalweit , Ignacio Mastroleo , Philipp Poxleitner , Marc Metzger , Joschka Boedecker , Maria Kalweit

Brain atrophy is an important biomarker for monitoring neurodegeneration and disease progression in conditions such as multiple sclerosis (MS). An accurate and robust quantitative measurement of brain volume change is paramount for…

Quantitative Methods · Quantitative Biology 2023-02-09 Geng Zhan , Dongang Wang , Mariano Cabezas , Lei Bai , Kain Kyle , Wanli Ouyang , Michael Barnett , Chenyu Wang

Whole abdominal organ segmentation is important in diagnosing abdomen lesions, radiotherapy, and follow-up. However, oncologists' delineating all abdominal organs from 3D volumes is time-consuming and very expensive. Deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Xiangde Luo , Wenjun Liao , Jianghong Xiao , Jieneng Chen , Tao Song , Xiaofan Zhang , Kang Li , Dimitris N. Metaxas , Guotai Wang , Shaoting Zhang

Pathological lymph node delineation is crucial in cancer diagnosis, progression assessment, and treatment planning. The MICCAI 2023 Lymph Node Quantification Challenge published the first public dataset for pathological lymph node…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Stefan M. Fischer , Johannes Kiechle , Daniel M. Lang , Jan C. Peeken , Julia A. Schnabel

Motivation: Accurate classification of mitotic figures into normal and atypical types is crucial for tumor prognostication in digital pathology. However, developing robust deep learning models for this task is challenging due to the subtle…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Sujatha Kotte , Vangala Govindakrishnan Saipradeep , Vidushi Walia , Dhandapani Nandagopal , Thomas Joseph , Naveen Sivadasan , Bhagat Singh Lali

Deep learning-based diagnostic performance increases with more annotated data, but large-scale manual annotations are expensive and labour-intensive. Experts evaluate diagnostic images during clinical routine, and write their findings in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Joeran S. Bosma , Anindo Saha , Matin Hosseinzadeh , Ilse Slootweg , Maarten de Rooij , Henkjan Huisman

From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot

The requirement for expert annotations limits the effectiveness of deep learning for medical image analysis. Although 3D self-supervised methods like volume contrast learning (VoCo) are powerful and partially address the labeling scarcity…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Po-Kai Chiu , Hung-Hsuan Chen