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Recent advancements in retinal surgery have paved the way for a modern operating room equipped with a surgical robot, a microscope, and intraoperative optical coherence tomography (iOCT)- a depth sensor widely used in retinal surgery.…

During retinal microsurgery, precise manipulation of the delicate retinal tissue is required for positive surgical outcome. However, accurate manipulation and navigation of surgical tools remain difficult due to a constrained workspace and…

Robotics · Computer Science 2020-11-17 Ji Woong Kim , Peiyao Zhang , Peter Gehlbach , Iulian Iordachita , Marin Kobilarov

Robotic platforms provide consistent and precise tool positioning that significantly enhances retinal microsurgery. Integrating such systems with intraoperative optical coherence tomography (iOCT) enables image-guided robotic interventions,…

In the last decade, various robotic platforms have been introduced that could support delicate retinal surgeries. Concurrently, to provide semantic understanding of the surgical area, recent advances have enabled microscope-integrated…

Vitreoretinal surgery is challenging even for expert surgeons owing to the delicate target tissues and the diminutive workspace in the retina. In addition to improved dexterity and accuracy, robot assistance allows for (partial) task…

Robotics · Computer Science 2022-04-29 Yuki Koyama , Murilo M. Marinho , Mamoru Mitsuishi , Kanako Harada

Retinal surgery is a complex activity that can be challenging for a surgeon to perform effectively and safely. Image guided robot-assisted surgery is one of the promising solutions that bring significant surgical enhancement in treatment…

Purpose. Intraoperative Optical Coherence Tomography (iOCT) is an increasingly available imaging technique for ophthalmic microsurgery that provides high-resolution cross-sectional information of the surgical scene. We propose to build on…

Computer Vision and Pattern Recognition · Computer Science 2018-02-20 Jakob Weiss , Nicola Rieke , Mohammad Ali Nasseri , Mathias Maier , Abouzar Eslami , Nassir Navab

A fundamental challenge in retinal surgery is safely navigating a surgical tool to a desired goal position on the retinal surface while avoiding damage to surrounding tissues, a procedure that typically requires tens-of-microns accuracy. In…

Several robotic frameworks have been recently developed to assist ophthalmic surgeons in performing complex vitreoretinal procedures such as subretinal injection of advanced therapeutics. These surgical robots show promising capabilities;…

Robotics · Computer Science 2025-02-26 Satoshi Inagaki , Alireza Alikhani , Nassir Navab , Peter C. Issa , M. Ali Nasseri

Ophthalmic surgical robots offer superior stability and precision by reducing the natural hand tremors of human surgeons, enabling delicate operations in confined surgical spaces. Despite the advancements in developing vision- and…

Robotics · Computer Science 2025-07-02 Tinghe Hong , Shenlin Cai , Boyang Li , Kai Huang

Subretinal injection is a delicate vitreoretinal procedure requiring precise needle placement within the subretinal space while avoiding perforation of the retinal pigment epithelium (RPE), a layer directly beneath the target with extremely…

Despite the extensive demonstration of robotic systems for both cataract and vitreoretinal procedures, existing technologies or mechanisms still possess insufficient accuracy, precision, and degrees of freedom for instrument manipulation or…

Robotics · Computer Science 2025-11-04 Yu-Ting Lai , Jacob Rosen , Yasamin Foroutani , Ji Ma , Wen-Cheng Wu , Jean-Pierre Hubschman , Tsu-Chin Tsao

Subretinal injection is a critical procedure for delivering therapeutic agents to treat retinal diseases such as age-related macular degeneration (AMD). However, retinal motion caused by physiological factors such as respiration and…

Ophthalmic microsurgery is known to be a challenging operation, which requires very precise and dexterous manipulation. Image guided robot-assisted surgery (RAS) is a promising solution that brings significant improvements in outcomes and…

Achieving precise control of robotic tool paths is often challenged by inherent system misalignments, unmodeled dynamics, and actuation inaccuracies. This work introduces an Iterative Learning Control (ILC) strategy to enable precise…

Robotics · Computer Science 2025-11-04 Yasamin Foroutani , Yasamin Mousavi-Motlagh , Aya Barzelay , Tsu-Chin Tsao

Purpose: The integration of multimodal imaging into operating rooms paves the way for comprehensive surgical scene understanding. In ophthalmic surgery, by now, two complementary imaging modalities are available: operating microscope (OPMI)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Nikolo Rohrmoser , Ghazal Ghazaei , Michael Sommersperger , Nassir Navab

This paper presents an innovative approach to intraoperative Optical Coherence Tomography (iOCT) image segmentation in ophthalmic surgery, leveraging statistical analysis of speckle patterns to incorporate statistical pathology-specific…

Image and Video Processing · Electrical Eng. & Systems 2024-10-27 Kristina Mach , Hessam Roodaki , Michael Sommersperger , Nassir Navab

In recent years, deep learning technology has developed rapidly, and the application of deep neural networks in the medical image processing field has become the focus of the spotlight. This paper aims to achieve needle position detection…

Image and Video Processing · Electrical Eng. & Systems 2023-02-17 Jidong Xu , Jinglun Yu , Jianing Yao , Rendong Zhang

Subretinal injection methods and other procedures for treating retinal conditions and diseases (many considered incurable) have been limited in scope due to limited human motor control. This study demonstrates the next generation,…

Exudative (wet) age-related macular degeneration (AMD) is a leading cause of vision loss in older adults, typically treated with intravitreal injections. Emerging therapies, such as subretinal injections of stem cells, gene therapy, small…

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