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Analysis of longitudinal changes in imaging studies often involves both segmentation of structures of interest and registration of multiple timeframes. The accuracy of such analysis could benefit from a tailored framework that jointly…

Computer Vision and Pattern Recognition · Computer Science 2021-02-25 Bo Li , Wiro J. Niessen , Stefan Klein , M. Arfan Ikram , Meike W. Vernooij , Esther E. Bron

We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Mikael Brudfors , Yaël Balbastre , Guillaume Flandin , Parashkev Nachev , John Ashburner

Longitudinal image registration enables studying temporal changes in brain morphology which is useful in applications where monitoring the growth or atrophy of specific structures is important. However this task is challenging due to;…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Aisha L. Shuaibu , Kieran A. Gibb , Peter A. Wijeratne , Ivor J. A. Simpson

Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted…

Machine Learning · Computer Science 2018-05-04 Ayush Jaiswal , Dong Guo , Cauligi S. Raghavendra , Paul Thompson

Longitudinal brain analysis is essential for understanding healthy aging and identifying pathological deviations. Longitudinal registration of sequential brain MRI underpins such analyses. However, existing methods are limited by reliance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Bailiang Jian , Jiazhen Pan , Yitong Li , Fabian Bongratz , Ruochen Li , Daniel Rueckert , Benedikt Wiestler , Christian Wachinger

In this paper we describe and validate a longitudinal method for whole-brain segmentation of longitudinal MRI scans. It builds upon an existing whole-brain segmentation method that can handle multi-contrast data and robustly analyze images…

Computer Vision and Pattern Recognition · Computer Science 2023-02-13 Stefano Cerri , Douglas N. Greve , Andrew Hoopes , Henrik Lundell , Hartwig R. Siebner , Mark Mühlau , Koen Van Leemput

Accurate registration of brain MRI scans is fundamental for cross-subject analysis in neuroscientific studies. This involves aligning both the cortical surface of the brain and the interior volume. Traditional methods treat volumetric and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-24 S. Mazdak Abulnaga , Andrew Hoopes , Malte Hoffmann , Robin Magnet , Maks Ovsjanikov , Lilla Zöllei , John Guttag , Bruce Fischl , Adrian Dalca

The human brain undergoes dynamic, potentially pathology-driven, structural changes throughout a lifespan. Longitudinal Magnetic Resonance Imaging (MRI) and other neuroimaging data are valuable for characterizing trajectories of change…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Agampreet Aulakh , Nils D. Forkert , Matthias Wilms

Continuous sign language recognition (CSLR) requires precise spatio-temporal modeling to accurately recognize sequences of gestures in videos. Existing frameworks often rely on CNN-based spatial backbones combined with temporal convolution…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Ahmed Abul Hasanaath , Hamzah Luqman

Classification and segmentation are crucial in medical image analysis as they enable accurate diagnosis and disease monitoring. However, current methods often prioritize the mutual learning features and shared model parameters, while…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Kai Ren , Ke Zou , Xianjie Liu , Yidi Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

We present a keypoint-based foundation model for general purpose brain MRI registration, based on the recently-proposed KeyMorph framework. Our model, called BrainMorph, serves as a tool that supports multi-modal, pairwise, and scalable…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Alan Q. Wang , Rachit Saluja , Heejong Kim , Xinzi He , Adrian Dalca , Mert R. Sabuncu

Early surgical treatment of brain tumors is crucial in reducing patient mortality rates. However, brain tissue deformation (called brain shift) occurs during the surgery, rendering pre-operative images invalid. As a cost-effective and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Soorena Salari , Amirhossein Rasoulian , Hassan Rivaz , Yiming Xiao

Recent studies have shown great promise in unsupervised representation learning (URL) for multivariate time series, because URL has the capability in learning generalizable representation for many downstream tasks without using inaccessible…

Machine Learning · Computer Science 2024-08-20 Zhiyu Liang , Jianfeng Zhang , Chen Liang , Hongzhi Wang , Zheng Liang , Lujia Pan

Machine learning analysis of longitudinal neuroimaging data is typically based on supervised learning, which requires a large number of ground-truth labels to be informative. As ground-truth labels are often missing or expensive to obtain…

Machine Learning · Computer Science 2021-06-29 Qingyu Zhao , Zixuan Liu , Ehsan Adeli , Kilian M. Pohl

The growing availability of longitudinal Magnetic Resonance Imaging (MRI) datasets has facilitated Artificial Intelligence (AI)-driven modeling of disease progression, making it possible to predict future medical scans for individual…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Lemuel Puglisi , Daniel C. Alexander , Daniele Ravì

Longitudinal magnetic resonance imaging data is used to model trajectories of change in brain regions of interest to identify areas susceptible to atrophy in those with neurodegenerative conditions like Alzheimer's disease. Most methods for…

Applications · Statistics 2024-07-25 Robert Zielinski , Kun Meng , Ani Eloyan

Numerical modeling of different structural materials that have highly nonlinear behaviors has always been a challenging problem in engineering disciplines. Experimental data is commonly used to characterize this behavior. This study aims to…

Machine Learning · Computer Science 2020-07-28 Elif Ecem Bas , Denis Aslangil , Mohamed A. Moustafa

Analyzing and predicting brain aging is essential for early prognosis and accurate diagnosis of cognitive diseases. The technique of neuroimaging, such as Magnetic Resonance Imaging (MRI), provides a noninvasive means of observing the aging…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Jingru Fu , Antonios Tzortzakakis , José Barroso , Eric Westman , Daniel Ferreira , Rodrigo Moreno

Segmenting deep brain structures from magnetic resonance images is important for patient diagnosis, surgical planning, and research. Most current state-of-the-art solutions follow a segmentation-by-registration approach, where subject MRIs…

Image and Video Processing · Electrical Eng. & Systems 2022-05-20 Mehri Baniasadi , Mikkel V. Petersen , Jorge Goncalves , Andreas Horn , Vanja Vlasov , Frank Hertel , Andreas Husch

Brain imaging analysis is fundamental in neuroscience, providing valuable insights into brain structure and function. Traditional workflows follow a sequential pipeline-brain extraction, registration, segmentation, parcellation, network…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Yao Su , Keqi Han , Mingjie Zeng , Lichao Sun , Liang Zhan , Carl Yang , Lifang He , Xiangnan Kong
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