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Whole Slide Imaging (WSI) is a cornerstone of digital pathology, offering detailed insights critical for diagnosis and research. Yet, the gigapixel size of WSIs imposes significant computational challenges, limiting their practical utility.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-15 Ravi Kant Gupta , Shounak Das , Amit Sethi

Due to the recent advancements in machine vision, digital pathology has gained significant attention. Histopathology images are distinctly rich in visual information. The tissue glass slide images are utilized for disease diagnosis.…

Image and Video Processing · Electrical Eng. & Systems 2020-11-02 Danial Maleki , Mehdi Afshari , Morteza Babaie , H. R. Tizhoosh

Artificial intelligence has started to transform histopathology impacting clinical diagnostics and biomedical research. However, while many computational pathology approaches have been proposed, most current AI models are limited with…

Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…

Computer Vision and Pattern Recognition · Computer Science 2017-09-08 Marc Aubreville , Maximilian Krappmann , Christof Bertram , Robert Klopfleisch , Andreas Maier

Computational pathology and whole-slide image (WSI) analysis are pivotal in cancer diagnosis and prognosis. However, the ultra-high resolution of WSIs presents significant modeling challenges. Recent advancements in pathology foundation…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Honglin Li , Zhongyi Shui , Yunlong Zhang , Chenglu Zhu , Lin Yang

Vision transformers (ViT) have been shown to allow for more flexible feature detection and can outperform convolutional neural network (CNN) when pre-trained on sufficient data. Due to their promising feature detection capabilities, we…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Nghia , Nguyen , Amer Wahed , Andy Quesada , Yasir Ali , Hanadi El Achi , Y. Helen Zhang , Jocelyn Ursua , Alex Banerjee , Sahib Kalra , L. Jeffrey Medeiros , Jie Xu

Prostate cancer is the most prevalent cancer among men in Western countries, with 1.1 million new diagnoses every year. The gold standard for the diagnosis of prostate cancer is a pathologists' evaluation of prostate tissue. To potentially…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Hans Pinckaers , Wouter Bulten , Jeroen van der Laak , Geert Litjens

Automated skin lesion analysis is very crucial in clinical practice, as skin cancer is among the most common human malignancy. Existing approaches with deep learning have achieved remarkable performance on this challenging task, however,…

Computer Vision and Pattern Recognition · Computer Science 2019-09-06 Xueying Shi , Qi Dou , Cheng Xue , Jing Qin , Hao Chen , Pheng-Ann Heng

Metadata are general characteristics of the data in a well-curated and condensed format, and have been proven to be useful for decision making, knowledge discovery, and also heterogeneous data organization of biobank. Among all data types…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Wei-Hung Weng , Yuannan Cai , Angela Lin , Fraser Tan , Po-Hsuan Cameron Chen

Whole slide image (WSI) analysis in digital pathology presents unique challenges due to the gigapixel resolution of WSIs and the scarcity of dense supervision signals. While Multiple Instance Learning (MIL) is a natural fit for slide-level…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Sofiène Boutaj , Marin Scalbert , Pierre Marza , Florent Couzinie-Devy , Maria Vakalopoulou , Stergios Christodoulidis

Neural networks promise to bring robust, quantitative analysis to medical fields, but adoption is limited by the technicalities of training these networks. To address this translation gap between medical researchers and neural networks in…

Image and Video Processing · Electrical Eng. & Systems 2019-02-20 Brendon Lutnick , Brandon Ginley , Darshana Govind , Sean D. McGarry , Peter S. LaViolette , Rabi Yacoub , Sanjay Jain , John E. Tomaszewski , Kuang-Yu Jen , Pinaki Sarder

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

In Recent Years, Digital Technologies Have Made Significant Strides In Augmenting-Human-Health, Cognition, And Perception, Particularly Within The Field Of Computational-Pathology. This Paper Presents A Novel Approach To Enhancing The…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Xiaoqian Hu

The examination of histopathology images is considered to be the gold standard for the diagnosis and stratification of cancer patients. A key challenge in the analysis of such images is their size, which can run into the gigapixels and can…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Joseph Boyd , Mykola Liashuha , Eric Deutsch , Nikos Paragios , Stergios Christodoulidis , Maria Vakalopoulou

Recent advances in machine learning are transforming medical image analysis, particularly in cancer detection and classification. Techniques such as deep learning, especially convolutional neural networks (CNNs) and vision transformers…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Arezoo Borji , Gernot Kronreif , Bernhard Angermayr , Sepideh Hatamikia

Vision Transformers are at the heart of the current surge of interest in foundation models for histopathology. They process images by breaking them into smaller patches following a regular grid, regardless of their content. Yet, not all…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Clément Grisi , Geert Litjens , Jeroen van der Laak

Most uses of Meta-Learning in visual recognition are very often applied to image classification, with a relative lack of works in other tasks {such} as segmentation and detection. We propose a generic Meta-Learning framework for few-shot…

Computer Vision and Pattern Recognition · Computer Science 2023-05-12 Hugo Oliveira , Pedro H. T. Gama , Isabelle Bloch , Roberto Marcondes Cesar

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Noriaki Hashimoto , Daisuke Fukushima , Ryoichi Koga , Yusuke Takagi , Kaho Ko , Kei Kohno , Masato Nakaguro , Shigeo Nakamura , Hidekata Hontani , Ichiro Takeuchi
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