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Diabetic retinopathy (DR) is a leading cause of blindness worldwide and a common complication of diabetes. As two different imaging tools for DR grading, color fundus photography (CFP) and infrared fundus photography (IFP) are…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Fan Xiao , Junlin Hou , Ruiwei Zhao , Rui Feng , Haidong Zou , Lina Lu , Yi Xu , Juzhao Zhang

Glaucoma is a complex group of eye diseases marked by optic nerve damage, commonly linked to elevated intraocular pressure and biomarkers like retinal nerve fiber layer thickness. Understanding how these biomarkers interact is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-24 Cheng Huang , Weizheng Xie , Tsengdar Lee , Karanjit Kooner , Ning Zhang , Jia Zhang

Glaucoma is a top cause of irreversible blindness globally, making early detection and longitudinal follow-up pivotal to preventing permanent vision loss. Current screening and progression assessment, however, rely on single tests or…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Wenbin Wei , Suyuan Yao , Cheng Huang , Xiangyu Gao

In this manuscript, we automate the procedure of grading of diabetic retinopathy and macular edema from fundus images using an ensemble of convolutional neural networks. The availability of limited amount of labeled data to perform…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Avinash Kori , Sai Saketh Chennamsetty , Mohammed Safwan K. P. , Varghese Alex

Foundation models (FMs) have shown great promise in medical image analysis by improving generalization across diverse downstream tasks. In ophthalmology, several FMs have recently emerged, but there is still no clear answer to fundamental…

Automatic diagnosis techniques have evolved to identify age-related macular degeneration (AMD) by employing single modality Fundus images or optical coherence tomography (OCT). To classify ocular diseases, fundus and OCT images are the most…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Pragya Gupta , Subhamoy Mandal , Debashree Guha , Debjani Chakraborty

The optic nerve head (ONH) typically experiences complex neural- and connective-tissue structural changes with the development and progression of glaucoma, and monitoring these changes could be critical for improved diagnosis and prognosis…

For accurate glaucoma diagnosis and monitoring, reliable retinal layer segmentation in OCT images is essential. However, existing 2D segmentation methods often suffer from slice-to-slice inconsistencies due to the lack of contextual…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Hyunwoo Kim , Heesuk Kim , Wungrak Choi , Jae-Sang Hyun

Purpose: The optic nerve head (ONH) undergoes complex and deep 3D morphological changes during the development and progression of glaucoma. Optical coherence tomography (OCT) is the current gold standard to visualize and quantify these…

Image and Video Processing · Electrical Eng. & Systems 2022-04-21 Fabian A. Braeu , Alexandre H. Thiéry , Tin A. Tun , Aiste Kadziauskiene , George Barbastathis , Tin Aung , Michaël J. A. Girard

In this paper, we present a self-training-based framework for glaucoma grading using OCT B-scans under the presence of domain shift. Particularly, the proposed two-step learning methodology resorts to pseudo-labels generated during the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-24 Gabriel García , Adrián Colomer , Rafael Verdú-Monedero , José Dolz , Valery Naranjo

Previous approaches using deep learning algorithms to classify glaucomatous damage on fundus photographs have been limited by the requirement for human labeling of a reference training set. We propose a new approach using spectral-domain…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Felipe A. Medeiros , Alessandro A. Jammal , Atalie C. Thompson

Existing multi-modal learning methods on fundus and OCT images mostly require both modalities to be available and strictly paired for training and testing, which appears less practical in clinical scenarios. To expand the scope of clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Lehan Wang , Chongchong Qi , Chubin Ou , Lin An , Mei Jin , Xiangbin Kong , Xiaomeng Li

Objective: To develop an explainable multimodal large language model (MM-LLM) that (1) screens optic nerve head (ONH) OCT circle scans for quality and (2) generates structured clinical reports that include glaucoma diagnosis and sector-wise…

Observing retinal fundus images by an ophthalmologist is a major diagnosis approach for glaucoma. However, it is still difficult to distinguish the features of the lesion solely through manual observations, especially, in glaucoma early…

Image and Video Processing · Electrical Eng. & Systems 2020-01-08 Peng Liu , Ruogu Fang

Glaucoma is the number one cause of irreversible blindness globally. A major challenge for accurate glaucoma detection and progression forecasting is the bottleneck of limited labeled patients with the state-of-the-art (SOTA) 3D retinal…

Computer Vision and Pattern Recognition · Computer Science 2023-08-28 Yan Luo , Min Shi , Yu Tian , Tobias Elze , Mengyu Wang

Deep learning and computer vision methods are nowadays predominantly used in the field of ophthalmology. In this paper, we present an attention-aided DenseNet-121 for classifying normal and glaucomatous eyes from fundus images. It involves…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Soham Chakraborty , Ayush Roy , Payel Pramanik , Daria Valenkova , Ram Sarkar

We propose a new method for training convolutional neural networks which integrates reinforcement learning along with supervised learning and use ti for transfer learning for classification of glaucoma from colored fundus images. The…

Image and Video Processing · Electrical Eng. & Systems 2021-05-19 Hardit Singh , Simarjeet Saini , Vasudevan Lakshminarayanan

Vision-Language Models (VLMs) have achieved remarkable success on multimodal tasks such as image-text retrieval and zero-shot classification, yet they can exhibit demographic biases even when explicit protected attributes are absent during…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Ahsan Habib Akash , Greg Murray , Annahita Amireskandari , Joel Palko , Carol Laxson , Binod Bhattarai , Prashnna Gyawali

Purpose: (1) To assess the performance of geometric deep learning (PointNet) in diagnosing glaucoma from a single optical coherence tomography (OCT) 3D scan of the optic nerve head (ONH); (2) To compare its performance to that obtained with…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Alexandre H. Thiery , Fabian Braeu , Tin A. Tun , Tin Aung , Michael J. A. Girard

Glaucoma is a severe eye disease that is known to deteriorate optic never fibers, causing cup size to increase, which could result in permanent loss of vision. Glaucoma is the second leading cause of blindness after cataract, but glaucoma…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Maleeha Khalid Khan , Syed Muhammad Anwar