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With the rapid development of biomedical software and hardware, a large amount of relational data interlinking genes, proteins, chemical components, drugs, diseases, and symptoms has been collected for modern biomedical research. Many…

Artificial Intelligence · Computer Science 2021-01-21 Yankai Chen , Yaozu Wu , Shicheng Ma , Irwin King

Most of the existing deep learning-based sequential recommendation approaches utilize the recurrent neural network architecture or self-attention to model the sequential patterns and temporal influence among a user's historical behavior and…

Information Retrieval · Computer Science 2022-01-17 Liwei Huang , Yutao Ma , Yanbo Liu , Bohong , Du , Shuliang Wang , Deyi Li

Graph convolutional networks (GCNs) can effectively capture the features of related nodes and improve the performance of the model. More attention is paid to employing GCN in Skeleton-Based action recognition. But existing methods based on…

Computer Vision and Pattern Recognition · Computer Science 2020-12-08 Tingwei Li , Ruiwen Zhang , Qing Li

Recently, there has been a growing interest in predicting human motion, which involves forecasting future body poses based on observed pose sequences. This task is complex due to modeling spatial and temporal relationships. The most…

Computer Vision and Pattern Recognition · Computer Science 2023-04-12 Hongwei Ren , Yuhong Shi , Kewei Liang

Graph Convolutional Networks (GCNs), which model skeleton data as graphs, have obtained remarkable performance for skeleton-based action recognition. Particularly, the temporal dynamic of skeleton sequence conveys significant information in…

Computer Vision and Pattern Recognition · Computer Science 2020-12-17 Jianan Li , Xuemei Xie , Zhifu Zhao , Yuhan Cao , Qingzhe Pan , Guangming Shi

With the arrival of the big data era, more and more data are becoming readily available in various real-world applications and those data are usually highly heterogeneous. Taking computational medicine as an example, we have both Electronic…

Machine Learning · Computer Science 2019-05-08 Xi Sheryl Zhang , Jingyuan Chou , Fei Wang

Effectively detecting anomalous nodes in attributed networks is crucial for the success of many real-world applications such as fraud and intrusion detection. Existing approaches have difficulties with three major issues: sparsity and…

Machine Learning · Computer Science 2020-10-01 Yulong Pei , Tianjin Huang , Werner van Ipenburg , Mykola Pechenizkiy

Structural information about protein-protein interactions, often missing at the interactome scale, is important for mechanistic understanding of cells and rational discovery of therapeutics. Protein docking provides a computational…

Biomolecules · Quantitative Biology 2020-12-17 Yue Cao , Yang Shen

Motivation: Biomedical knowledge graphs (KGs) are crucial for drug discovery and disease understanding, yet their completion and reasoning are challenging. Knowledge Embedding (KE) methods capture global semantics but struggle with dynamic…

Artificial Intelligence · Computer Science 2025-07-23 Yitong Lin , Jiaying He , Jiahe Chen , Xinnan Zhu , Jianwei Zheng , Tao Bo

The graph structure is a commonly used data storage mode, and it turns out that the low-dimensional embedded representation of nodes in the graph is extremely useful in various typical tasks, such as node classification, link prediction ,…

Social and Information Networks · Computer Science 2020-08-03 Xing Li , Wei Wei , Xiangnan Feng , Xue Liu , Zhiming Zheng

Graph Convolutional Networks (GCNs) have recently become the primary choice for learning from graph-structured data, superseding hash fingerprints in representing chemical compounds. However, GCNs lack the ability to take into account the…

Machine Learning · Computer Science 2020-07-03 Tomasz Danel , Przemysław Spurek , Jacek Tabor , Marek Śmieja , Łukasz Struski , Agnieszka Słowik , Łukasz Maziarka

Several brain disorders can be detected by observing alterations in the brain's structural and functional connectivities. Neurological findings suggest that early diagnosis of brain disorders, such as mild cognitive impairment (MCI), can…

Neurons and Cognition · Quantitative Biology 2021-10-22 Alpay Tekin , Ahmed Nebli , Islem Rekik

Accurate prediction of molecular properties is essential in drug discovery and related fields. However, existing graph neural networks (GNNs) often struggle to simultaneously capture both local and global molecular structures. In this work,…

Machine Learning · Computer Science 2025-08-26 XiaYu Liu , Chao Fan , Yang Liu , Hou-biao Li

The ongoing need for effective epidemic modeling has driven advancements in capturing the complex dynamics of infectious diseases. Traditional models, such as Susceptible-Infected-Recovered, and graph-based approaches often fail to account…

Social and Information Networks · Computer Science 2025-04-02 Songyuan Liu , Shengbo Gong , Tianning Feng , Zewen Liu , Max S. Y. Lau , Wei Jin

Accurate temporal segmentation of human actions is critical for intelligent robots in collaborative settings, where a precise understanding of sub-activity labels and their temporal structure is essential. However, the inherent noise in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Hao Xing , Kai Zhe Boey , Yuankai Wu , Darius Burschka , Gordon Cheng

Geometric deep learning has demonstrated a great potential in non-Euclidean data analysis. The incorporation of geometric insights into learning architecture is vital to its success. Here we propose a curvature-enhanced graph convolutional…

Quantitative Methods · Quantitative Biology 2023-06-27 Cong Shen , Pingjian Ding , Junjie Wee , Jialin Bi , Jiawei Luo , Kelin Xia

Image-based characterization and disease understanding involve integrative analysis of morphological, spatial, and topological information across biological scales. The development of graph convolutional networks (GCNs) has created the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-22 Kexin Ding , Mu Zhou , Zichen Wang , Qiao Liu , Corey W. Arnold , Shaoting Zhang , Dimitri N. Metaxas

Accurate identification and localisation of brain tumours from medical images remain challenging due to tumour variability and structural complexity. Convolutional Neural Networks (CNNs), particularly ResNet and Unet, have made significant…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Peixin Dai , Jingsi Zhang , Zhitao Shu

Emotion recognition is essential in the diagnosis and rehabilitation of various mental diseases. In the last decade, electroencephalogram (EEG)-based emotion recognition has been intensively investigated due to its prominative accuracy and…

Human-Computer Interaction · Computer Science 2024-08-22 Ming Jin , Enwei Zhu , Changde Du , Huiguang He , Jinpeng Li

Evaluating the blood-brain barrier (BBB) permeability of drug molecules is a critical step in brain drug development. Traditional methods for the evaluation require complicated in vitro or in vivo testing. Alternatively, in silico…

Quantitative Methods · Quantitative Biology 2022-04-07 Yan Ding , Xiaoqian Jiang , Yejin Kim