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Related papers: Applying Large Language Models for Causal Structur…

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The causal capabilities of large language models (LLMs) are a matter of significant debate, with critical implications for the use of LLMs in societally impactful domains such as medicine, science, law, and policy. We conduct a "behavorial"…

Artificial Intelligence · Computer Science 2024-08-21 Emre Kıcıman , Robert Ness , Amit Sharma , Chenhao Tan

Clinical Decision Support Systems (CDSS) utilize evidence-based knowledge and patient data to offer real-time recommendations, with Large Language Models (LLMs) emerging as a promising tool to generate plain-text explanations for medical…

Computation and Language · Computer Science 2023-10-04 D. Umerenkov , G. Zubkova , A. Nesterov

Large language models (LLMs) are trained on enormous amounts of data and encode knowledge in their parameters. We propose a pipeline to elicit causal relationships from LLMs. Specifically, (i) we sample many documents from LLMs on a given…

Machine Learning · Computer Science 2026-03-05 Takashi Kameyama , Masahiro Kato , Yasuko Hio , Yasushi Takano , Naoto Minakawa

Large Language Models (LLMs) have shown their success in language understanding and reasoning on general topics. However, their capability to perform inference based on user-specified structured data and knowledge in corpus-rare concepts,…

Computation and Language · Computer Science 2024-10-29 Haitao Jiang , Lin Ge , Yuhe Gao , Jianian Wang , Rui Song

To perform effective causal inference in high-dimensional datasets, initiating the process with causal discovery is imperative, wherein a causal graph is generated based on observational data. However, obtaining a complete and accurate…

Machine Learning · Computer Science 2025-04-18 Elahe Khatibi , Mahyar Abbasian , Zhongqi Yang , Iman Azimi , Amir M. Rahmani

Designing proper experiments and selecting optimal intervention targets is a longstanding problem in scientific or causal discovery. Identifying the underlying causal structure from observational data alone is inherently difficult.…

Artificial Intelligence · Computer Science 2025-03-05 Junyi Li , Yongqiang Chen , Chenxi Liu , Qianyi Cai , Tongliang Liu , Bo Han , Kun Zhang , Hui Xiong

Large language models (LLMs) are introducing a paradigm shift in molecular discovery by enabling text-guided interaction with chemical spaces through natural language, symbolic notations, with emerging extensions to incorporate multi-modal…

Machine Learning · Computer Science 2025-05-23 Ziqing Wang , Kexin Zhang , Zihan Zhao , Yibo Wen , Abhishek Pandey , Han Liu , Kaize Ding

Large Language Models (LLMs) have recently shown great promise in planning and reasoning applications. These tasks demand robust systems, which arguably require a causal understanding of the environment. While LLMs can acquire and reflect…

Artificial Intelligence · Computer Science 2024-10-29 John Gkountouras , Matthias Lindemann , Phillip Lippe , Efstratios Gavves , Ivan Titov

The validity of medical studies based on real-world clinical data, such as observational studies, depends on critical assumptions necessary for drawing causal conclusions about medical interventions. Many published studies are flawed…

Artificial Intelligence · Computer Science 2024-07-30 Ahmed Alaa , Rachael V. Phillips , Emre Kıcıman , Laura B. Balzer , Mark van der Laan , Maya Petersen

Causality is essential in scientific research, enabling researchers to interpret true relationships between variables. These causal relationships are often represented by causal graphs, which are directed acyclic graphs. With the recent…

Computation and Language · Computer Science 2025-02-19 Ivaxi Sheth , Bahare Fatemi , Mario Fritz

Causal discovery seeks to uncover causal relations from data, typically represented as causal graphs, and is essential for predicting the effects of interventions. While expert knowledge is required to construct principled causal graphs,…

Artificial Intelligence · Computer Science 2026-02-19 Zihao Li , Fabrizio Russo

Large Language Models (LLMs) have revolutionised the field of Natural Language Processing (NLP) and have achieved state-of-the-art performance in practically every task in this field. However, the prevalent approach used in text generation,…

Computation and Language · Computer Science 2024-08-12 Nicolo Micheletti , Samuel Belkadi , Lifeng Han , Goran Nenadic

We assess the ability of large language models (LLMs) to answer causal questions by analyzing their strengths and weaknesses against three types of causal question. We believe that current LLMs can answer causal questions with existing…

Objective: This study investigates the potential of Large Language Models (LLMs) as an alternative to human expert elicitation for extracting structured causal knowledge and facilitating causal modeling in biometric and healthcare…

Artificial Intelligence · Computer Science 2025-04-15 Olha Shaposhnyk , Daria Zahorska , Svetlana Yanushkevich

Causal inference has shown potential in enhancing the predictive accuracy, fairness, robustness, and explainability of Natural Language Processing (NLP) models by capturing causal relationships among variables. The emergence of generative…

Computation and Language · Computer Science 2025-03-24 Xiaoyu Liu , Paiheng Xu , Junda Wu , Jiaxin Yuan , Yifan Yang , Yuhang Zhou , Fuxiao Liu , Tianrui Guan , Haoliang Wang , Tong Yu , Julian McAuley , Wei Ai , Furong Huang

Estimating individualized treatment effects from observational data presents a persistent challenge due to unmeasured confounding and structural bias. Causal Machine Learning (causal ML) methods, such as causal trees and doubly robust…

Machine Learning · Computer Science 2025-08-12 Po-Han Lee , Yu-Cheng Lin , Chan-Tung Ku , Chan Hsu , Pei-Cing Huang , Ping-Hsun Wu , Yihuang Kang

Accurate prediction of treatment outcomes in lung cancer remains challenging due to the sparsity, heterogeneity, and contextual overload of real-world electronic health data. Traditional models often fail to capture semantic information…

Lung cancer is an extremely lethal disease primarily due to its late-stage diagnosis and significant mortality rate, making it the major cause of cancer-related demises globally. Machine Learning (ML) and Convolution Neural network (CNN)…

Image and Video Processing · Electrical Eng. & Systems 2025-01-03 Asha V , Bhavanishankar K

Causal reasoning is a cornerstone of human intelligence and a critical capability for artificial systems aiming to achieve advanced understanding and decision-making. This thesis delves into various dimensions of causal reasoning and…

Computation and Language · Computer Science 2025-04-22 Zhijing Jin

Large language models (LLMs) have emerged as transformative tools in medicine, with strong capabilities in language understanding, reasoning, and structured information extraction. Radiation oncology is particularly well suited for LLM…