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The emerging field of optogenetics allows for optical activation or inhibition of neurons and other tissue in the nervous system. In 2005 optogenetic proteins were expressed in the nematode C. elegans for the first time. Since then, C.…

Neurons and Cognition · Quantitative Biology 2013-05-13 Steven J. Husson , Alexander Gottschalk , Andrew M. Leifer

Traditional imitation learning provides a set of methods and algorithms to learn a reward function or policy from expert demonstrations. Learning from demonstration has been shown to be advantageous for navigation tasks as it allows for…

Robotics · Computer Science 2021-08-03 Christian Ellis , Maggie Wigness , John G. Rogers , Craig Lennon , Lance Fiondella

Continuous, adaptive learning, the ability to adapt to the environment and keep improving performance, is a hallmark of natural intelligence. Biological organisms excel in acquiring, transferring, and retaining knowledge while adapting to…

Neurons and Cognition · Quantitative Biology 2026-03-03 Jie Mei , Alejandro Rodriguez-Garcia , Daigo Takeuchi , Gabriel Wainstein , Nina Hubig , Yalda Mohsenzadeh , Srikanth Ramaswamy

Animals employ strategic decision-making while carefully weighing nutritional benefits against the risks presented by aversive or harmful stimuli in their natural environment, to maximize foraging efficiency, In India, free-ranging dogs…

Other Quantitative Biology · Quantitative Biology 2025-12-02 Tuhin Subhra Pal , Srijaya Nandi , Hindoli Gope , Aniket Malakar , Rohan Sarkar , Sagarika Biswas , Anindita Bhadra

The prediction of odor characters is still impossible based on the odorant molecular structure. We designed a CNN-based regressor for computed parameters in molecular vibrations (CNN\_vib), in order to investigate the ability to predict…

Chemical Physics · Physics 2025-09-23 Yuki Harada , Shuichi Maeda , Junwei Shen , Taku Misonou , Hirokazu Hori , Shinichiro Nakamura

Self-propelling organisms locomote via generation of patterns of self-deformation. Despite the diversity of body plans, internal actuation schemes and environments in limbless vertebrates and invertebrates, such organisms often use similar…

Undulatory swimming is a widespread propulsion strategy adopted by many small-scale organisms including various single-cell eukaryotes and nematodes. In this work, we report a comprehensive study of undulatory locomotion of a finite…

Fluid Dynamics · Physics 2015-06-16 R. Berman , O. Kenneth , J. Sznitman , A. Leshansky

We present a novel outdoor navigation algorithm to generate stable and efficient actions to navigate a robot to reach a goal. We use a multi-stage training pipeline and show that our approach produces policies that result in stable and…

Robotics · Computer Science 2022-12-07 Jing Liang , Kasun Weerakoon , Tianrui Guan , Nare Karapetyan , Dinesh Manocha

Navigation is a complex skill with a long history of research in animals and humans. In this work, we simulate the Morris Water Maze in 2D to train deep reinforcement learning agents. We perform automatic classification of navigation…

Machine Learning · Computer Science 2023-11-09 Andrew Liu , Alla Borisyuk

There is renewed interest in modeling and understanding the nervous system of the nematode $\textit{Caenorhabditis elegans}$ ($\textit{C. elegans}$), as this small model system provides a path to bridge the gap between nervous system…

Neurons and Cognition · Quantitative Biology 2025-05-20 Quilee Simeon , Anshul Kashyap , Konrad P Kording , Edward S Boyden

Navigation is crucial for animal behavior and is assumed to require an internal representation of the external environment, termed a cognitive map. The precise form of this representation is often considered to be a metric representation of…

Neurons and Cognition · Quantitative Biology 2020-02-10 Tie Xu , Omri Barak

Deep phenotyping is an emerging conceptual paradigm and experimental approach that seeks to measure many aspects of phenotypes and link them to understand the underlying biology. Successful deep phenotyping has mostly been applied in…

Quantitative Methods · Quantitative Biology 2019-04-03 Nan Xu , Dhaval S. Patel , Hang Lu

With the fast and unstoppable evolution of robotics and artificial intelligence, effective autonomous navigation in real-world scenarios has become one of the most pressing challenges in the literature. However, demanding requirements, such…

Robotics · Computer Science 2024-07-11 A. Novo , F. Lobon , H. G. De Marina , S. Romero , F. Barranco

Animals excel at adapting their intentions, attention, and actions to the environment, making them remarkably efficient at interacting with a rich, unpredictable and ever-changing external world, a property that intelligent machines…

Machine Learning · Computer Science 2019-12-09 Nicolas Vecoven , Damien Ernst , Antoine Wehenkel , Guillaume Drion

Many organisms navigate gradients by alternating straight motions (runs) with random reorientations (tumbles), transiently suppressing tumbles whenever attractant signal increases. This induces a functional coupling between movement and…

Cell Behavior · Quantitative Biology 2017-04-12 Junjiajia Long , Steven W. Zucker , Thierry Emonet

Many microorganisms live and evolve in complex fluids. Examples include mammalian spermatozoa in cervical mucus, worms (e.g., \textit{C. elegans}) in wet soil, and bacteria (e.g., \textit{H. pylori}) in our stomach lining. Due to the…

Fluid Dynamics · Physics 2022-10-21 Paulo E. Arratia

Recent work has explored the problem of autonomous navigation by imitating a teacher and learning an end-to-end policy, which directly predicts controls from raw images. However, these approaches tend to be sensitive to mistakes by the…

Computer Vision and Pattern Recognition · Computer Science 2019-05-24 Guohao Li , Matthias Müller , Vincent Casser , Neil Smith , Dominik L. Michels , Bernard Ghanem

Artificial neural networks face the stability-plasticity dilemma in continual learning, while the brain can maintain memories and remain adaptable. However, the biological strategies for continual learning and their potential to inspire…

Machine Learning · Computer Science 2025-02-04 Heming Zou , Yunliang Zang , Xiangyang Ji

How can animals behave effectively in conditions involving different motivational contexts? Here, we propose how reinforcement learning neural networks can learn optimal behavior for dynamically changing motivational salience vectors.…

Neurons and Cognition · Quantitative Biology 2019-11-20 Sergey A. Shuvaev , Ngoc B. Tran , Marcus Stephenson-Jones , Bo Li , Alexei A. Koulakov

Feature interaction selection is a fundamental problem in commercial recommender systems. Most approaches equally enumerate all features and interactions by the same pre-defined operation under expert guidance. Their recommendation is…

Artificial Intelligence · Computer Science 2024-05-30 Runlong Yu , Qixiang Shao , Qi Liu , Huan Liu , Enhong Chen
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