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Modern medical image segmentation methods primarily use discrete representations in the form of rasterized masks to learn features and generate predictions. Although effective, this paradigm is spatially inflexible, scales poorly to…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Yejia Zhang , Pengfei Gu , Nishchal Sapkota , Danny Z. Chen

In this paper, we develop a deep learning approach for the accurate solution of challenging problems of near-field microscopy that leverages the powerful framework of physics-informed neural networks (PINNs) for the inversion of the complex…

Optics · Physics 2024-06-12 Yuyao Chen , Luca Dal Negro

Image segmentation is a fundamental topic in image processing and has been studied for many decades. Deep learning-based supervised segmentation models have achieved state-of-the-art performance but most of them are limited by using…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 Xu Chen , Xiangde Luo , Yitian Zhao , Shaoting Zhang , Guotai Wang , Yalin Zheng

Annotation of medical images has been a major bottleneck for the development of accurate and robust machine learning models. Annotation is costly and time-consuming and typically requires expert knowledge, especially in the medical domain.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Holger Roth , Ling Zhang , Dong Yang , Fausto Milletari , Ziyue Xu , Xiaosong Wang , Daguang Xu

We introduce NeuroPINNs, a neuroscience-inspired extension of Physics-Informed Neural Networks (PINNs) that incorporates biologically motivated spiking neuron models to achieve energy-efficient PDE solving. Unlike conventional PINNs, which…

Computational Physics · Physics 2025-11-11 Shailesh Garg , Souvik Chakraborty

Implicit neural representations (INRs) have achieved remarkable successes in learning expressive yet compact signal representations. However, they are not naturally amenable to predictive tasks such as segmentation, where they must learn…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Kushal Vyas , Ashok Veeraraghavan , Guha Balakrishnan

Segmentation of organs or lesions from medical images plays an essential role in many clinical applications such as diagnosis and treatment planning. Though Convolutional Neural Networks (CNN) have achieved the state-of-the-art performance…

Computer Vision and Pattern Recognition · Computer Science 2021-05-27 Xiangde Luo , Guotai Wang , Tao Song , Jingyang Zhang , Michael Aertsen , Jan Deprest , Sebastien Ourselin , Tom Vercauteren , Shaoting Zhang

Semantic segmentation models trained on public datasets have achieved great success in recent years. However, these models didn't consider the personalization issue of segmentation though it is important in practice. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2021-09-07 Yu Zhang , Chang-Bin Zhang , Peng-Tao Jiang , Ming-Ming Cheng , Feng Mao

Physical modeling method, represented by simulation and visualization of the principles in physics, is introduced in the shape extraction of the active contours. The objectives of adopting this concept are to address the several major…

Computer Vision and Pattern Recognition · Computer Science 2009-06-30 Hongyu Lu , Shanglian Bao

With growing investigations into solving partial differential equations by physics-informed neural networks (PINNs), more accurate and efficient PINNs are required to meet the practical demands of scientific computing. One bottleneck of…

Machine Learning · Computer Science 2025-10-29 Tianchi Yu , Yiming Qi , Ivan Oseledets , Shiyi Chen

Physics-informed neural networks (PINNs), owing to their mesh-free nature, offer a powerful approach for solving high-dimensional partial differential equations (PDEs) in complex geometries, including irregular domains. This capability…

Numerical Analysis · Mathematics 2025-06-06 Hanfei Zhou , Lei Shi

Semantic segmentation of medical images is an essential first step in computer-aided diagnosis systems for many applications. However, given many disparate imaging modalities and inherent variations in the patient data, it is difficult to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Bhavani Sambaturu , Ashutosh Gupta , C. V. Jawahar , Chetan Arora

ChIP-seq, which combines chromatin immunoprecipitation with massively parallel short-read sequencing, can profile in vivo genome-wide transcription factor-DNA association with higher sensitivity, specificity and spatial resolution than…

Genomics · Quantitative Biology 2009-03-19 Xuekui Zhang , Gordon Robertson , Martin Krzywinski , Kaida Ning , Arnaud Droit , Steven Jones , Raphael Gottardo

Introducing explicit constraints on the structural predictions has been an effective way to improve the performance of semantic segmentation models. Existing methods are mainly based on insufficient hand-crafted rules that only partially…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Boxi Wu , Shuai Zhao , Wenqing Chu , Zheng Yang , Deng Cai

Image segmentation is a fundamental and challenging problem in computer vision with applications spanning multiple areas, such as medical imaging, remote sensing, and autonomous vehicles. Recently, convolutional neural networks (CNNs) have…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Ali Hatamizadeh

Physics-informed neural networks (PINNs) are a versatile tool in the burgeoning field of scientific machine learning for solving partial differential equations (PDEs). However, determining suitable training strategies for them is not…

Numerical Analysis · Mathematics 2026-03-09 Saad Qadeer , Panos Stinis

Whilst the partial differential equations that govern the dynamics of our world have been studied in great depth for centuries, solving them for complex, high-dimensional conditions and domains still presents an incredibly large…

Machine Learning · Computer Science 2023-03-07 Edward Small

Deep learning techniques have shown their success in medical image segmentation since they are easy to manipulate and robust to various types of datasets. The commonly used loss functions in the deep segmentation task are pixel-wise loss…

Image and Video Processing · Electrical Eng. & Systems 2022-10-10 Yuan Lan , Yang Xiang , Luchan Zhang

Precise object boundary detection for automatic image segmentation is critical for image analysis, including that used in computer-aided diagnosis. However, such detection traditionally uses active contour or snake models requiring accurate…

Image and Video Processing · Electrical Eng. & Systems 2021-06-14 Sinan Onal , Xin Chen , Madagedara Maduka Balasooriya

From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot