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We describe a class of growth algorithms for finding low energy states of heteropolymers. These polymers form toy models for proteins, and the hope is that similar methods will ultimately be useful for finding native states of real proteins…

Soft Condensed Matter · Physics 2007-05-23 Peter Grassberger

In Machine Learning, a benchmark refers to an ensemble of datasets associated with one or multiple metrics together with a way to aggregate different systems performances. They are instrumental in (i) assessing the progress of new methods…

Computation and Language · Computer Science 2022-10-10 Pierre Colombo , Nathan Noiry , Ekhine Irurozki , Stephan Clemencon

The steady progress of quantum hardware is motivating the search for novel quantum algorithm optimization strategies for near-term, real-world applications. In this study, we propose a novel feature map optimization strategy for Quantum…

Quantum Physics · Physics 2025-03-31 Roberto Moretti , Andrea Giachero , Voica Radescu , Michele Grossi

Because of increasing amounts of intermittent and distributed generators in power systems, many demand response programs have been developed to schedule flexible energy consumption. However, proper benchmarks for comparing these methods are…

Systems and Control · Electrical Eng. & Systems 2021-03-19 Koos van der Linden , Natalia Romero , Mathijs M. de Weerdt

In applications such as molecule design or drug discovery, it is desirable to have an algorithm which recommends new candidate molecules based on the results of past tests. These molecules first need to be synthesized and then tested for…

Bayesian optimization (BO) is an efficient framework for solving black-box optimization problems with expensive function evaluations. This paper addresses the BO problem setting for combinatorial spaces (e.g., sequences and graphs) that…

Machine Learning · Computer Science 2022-02-07 Aryan Deshwal , Syrine Belakaria , Janardhan Rao Doppa

As they can travel long distances, free space optical quantum states are good candidates for carrying information in quantum information technology protocols. These states, however, are often complex to produce and require protocols whose…

Optics · Physics 2014-12-08 Jean Etesse , Bhaskar Kanseri , Rosa Tualle-Brouri

Many forms of programmable matter have been proposed for various tasks. We use an abstract model of self-organizing particle systems for programmable matter which could be used for a variety of applications, including smart paint and…

Emerging Technologies · Computer Science 2017-10-24 Alexandra Porter , Andréa W. Richa

We show that the herding procedure of Welling (2009) takes exactly the form of a standard convex optimization algorithm--namely a conditional gradient algorithm minimizing a quadratic moment discrepancy. This link enables us to invoke…

Machine Learning · Computer Science 2012-09-12 Francis Bach , Simon Lacoste-Julien , Guillaume Obozinski

We describe an algorithm to compute the extremal eigenvalues and corresponding eigenvectors of a symmetric matrix by solving a sequence of Quadratic Binary Optimization problems. This algorithm is robust across many different classes of…

Emerging Technologies · Computer Science 2022-10-12 Benjamin Krakoff , Susan M. Mniszewski , Christian F. A. Negre

We develop a hyperparameter optimisation algorithm, Automated Budget Constrained Training (AutoBCT), which balances the quality of a model with the computational cost required to tune it. The relationship between hyperparameters, model…

Machine Learning · Statistics 2024-02-06 Lukas Cironis , Jan Palczewski , Georgios Aivaliotis

This study proposed an exhaustive stable/reproducible rule-mining algorithm combined to a classifier to generate both accurate and interpretable models. Our method first extracts rules (i.e., a conjunction of conditions about the values of…

Machine Learning · Computer Science 2017-07-03 Margaux Luck , Nicolas Pallet , Cecilia Damon

Extending a recent suggestion to generate new instances for numerical black-box optimization benchmarking by interpolating pairs of the well-established BBOB functions from the COmparing COntinuous Optimizers (COCO) platform, we propose in…

Machine Learning · Computer Science 2023-06-21 Diederick Vermetten , Furong Ye , Thomas Bäck , Carola Doerr

Optimizing over separable quantum objects is challenging for two key reasons: determining separability is NP-hard, and the dimensionality of the problem grows exponentially with the number of qubits. We address both challenges by…

Quantum Physics · Physics 2025-10-01 Ankith Mohan , Tobias Haug , Kishor Bharti , Jamie Sikora

Application-based benchmarks are increasingly used to quantify and compare quantum computers' performance. However, because contemporary quantum computers cannot run utility-scale computations, these benchmarks currently test this…

We present an approach to make molecular optimization more efficient. We infer a hypergraph replacement grammar from the ChEMBL database, count the frequencies of particular rules being used to expand particular nonterminals in other rules,…

Machine Learning · Statistics 2019-06-06 Egor Kraev , Mark Harley

Quadratic unconstrained binary optimization (QUBO) problems are well-studied, not least because they can be approached using contemporary quantum annealing or classical hardware acceleration. However, due to limited precision and hardware…

Quantum Physics · Physics 2023-07-06 Sascha Mücke , Thore Gerlach , Nico Piatkowski

In this paper we present a novel strategy to solve optimization problems within a hybrid quantum-classical scheme based on quantum annealing, with a particular focus on QUBO problems. The proposed algorithm is based on an iterative…

Quantum Physics · Physics 2020-04-07 Enrico Blanzieri , Davide Pastorello

State aggregation aims to reduce the computational complexity of solving Markov Decision Processes (MDPs) while preserving the performance of the original system. A fundamental challenge lies in optimizing policies within the aggregated, or…

Machine Learning · Computer Science 2025-10-14 Shuo Zhao , Yongqiang Li , Yu Feng , Zhongsheng Hou , Yuanjing Feng

Quadratic Unconstrained Binary Optimization (QUBO) provides a versatile framework for representing NP-hard combinatorial problems, yet existing solvers often face trade-offs among speed, accuracy, and scalability. In this work, we introduce…

Quantum Physics · Physics 2025-06-06 Jiecheng Yang , Ding Wang , Xiang Zhao , Hairui Zhang , Ming Gao , Lin Yang