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We consider a microfluidic mixer based on hydrodynamic focusing, which is used to initiate the folding process of individual proteins. The folding process is initiated by quickly diluting a local denaturant concentration, and we define…

Fluid Dynamics · Physics 2015-01-30 Benjamin Ivorra , Juana López Redondo , Ángel M. Ramos , Juan G. Santiago

Water condensation on superhydrophobic surfaces can generate spontaneous droplet jumping, enabling rapid condensate removal and improved thermal and mass transfer. Although this effect has been extensively demonstrated on densely packed…

We address the problem of designing micro-fluidic chips for sample preparation, which is a crucial step in many experimental processes in chemical and biological sciences. One of the objectives of sample preparation is to dilute the sample…

Data Structures and Algorithms · Computer Science 2019-11-07 Miguel Coviello Gonzalez , Marek Chrobak

Submillimeter air-borne drops of well defined size are notoriously difficult to produce in the lab. Here, we demonstrate that any simple droplet dripper, in which millimetric droplets are created by letting them drip under gravity from a…

Fluid Dynamics · Physics 2019-10-17 K. S. Surabhi , Sander Wildeman

Particle beams are important tools for probing atomic and molecular interactions. Here we demonstrate that particle beams also offer a unique opportunity to investigate interactions in macroscopic systems, such as granular media. Motivated…

Soft Condensed Matter · Physics 2015-05-19 Scott R. Waitukaitis , Helge F. Gruetjen , John R. Royer , Heinrich M. Jaeger

We combine theory, numerical simulation and experiments to investigate the breakup of two identical droplets entering a Y-junction with controlled spatial offset by which the second droplet trails the first. Based on fully resolved 3D…

Fluid Dynamics · Physics 2020-08-04 Simon Schütz , Jian Wei Khor , Sindy K. Y. Tang , Tobias M. Schneider

This study presents a three-dimensional transient computational fluid dynamics simulation of droplet generation in a flow-focusing microfluidic device using the Coupled Level Set and Volume of Fluid method for interface capturing. We…

Fluid Dynamics · Physics 2025-07-17 Manohar Jammula , Somasekhara Goud Sontti

Generation of graphs is a major challenge for real-world tasks that require understanding the complex nature of their non-Euclidean structures. Although diffusion models have achieved notable success in graph generation recently, they are…

Machine Learning · Computer Science 2024-06-04 Jaehyeong Jo , Dongki Kim , Sung Ju Hwang

The hydrodynamics of droplets is significant in wide-ranging applications involving immiscible fluids and emulsions in food and pharmaceutical. The control and manipulation of droplets are primarily a function of flow governing and…

Fluid Dynamics · Physics 2022-01-19 Akepogu Venkateshwarlu , Ram Prakash Bharti

In this work, we used a coupled level set and volume of fluid (CLSVOF) computational method for studying the generation of microdroplets in a two dimensional circular co-flow microfluidic device. The fundamental understanding of shear…

Fluid Dynamics · Physics 2025-07-17 Manohar Jammula , Somasekhara Goud Sontti

Micro droplets are extensively used in chemical, biological, and medical research, primarily for conducting various tests on samples, including living organisms, using a microfluidic framework. Recent studies have shown that the physiology…

Fluid Dynamics · Physics 2025-05-27 Siddhant Jain , Saini Jatin Rao , Shubhadeep Mandal , Cameron Tropea , Saptarshi Basu

3D-printed microfluidic devices offer new ways to study fluid dynamics. We present the first clear visualization of vortex breakdown in a dividing T-junction flow. By individual control of the inflow and two outflows, we decouple the…

Fluid Dynamics · Physics 2018-06-29 San To Chan , Simon J. Haward , Amy Q. Shen

In this article, we have developed a computational model to determine the droplet formation regime and its transition in a square microfluidic flow-focusing device that eventually dictate the droplet shape, size, and its formation…

Fluid Dynamics · Physics 2025-10-28 Somasekhara Goud Sontti , Arnab Atta

The mechanical properties of biological fluids can serve as early indicators of disease, offering valuable insights into complex physiological and pathological processes. However, the existing technologies can hardly support high throughput…

Optics · Physics 2025-09-18 Zhonghao Li , Zhihan Cai , Chaoyang Gong

One of the most widespread canonical devices for fluid mixing is the T-shaped mixer, in which two opposing miscible liquid streams meet at a junction and then mix along a main channel. Laminar steady and time-periodic flows in T-shaped…

Fluid Dynamics · Physics 2025-09-15 Huixin Li , Mohammad Mehdi Zamani Asl , Bastian Bäuerlein , Kerstin Avila , Duo Xu , Marc Avila

Controlling the shape and position of moving and pinned droplets on a solid surface is an important feature often found in microfluidic applications. However, automating them, e.g., for high-throughput applications, does rarely involve…

Fluid Dynamics · Physics 2020-07-09 Henning Bonart , Christian Kahle , Jens-Uwe Repke

Mixing at the microfluidic scale is challenging due to the low Reynolds numbers and often high P\'eclet numbers. Without turbulence, mixing relies solely on diffusion, resulting in slow and inefficient mixing. We demonstrate enhanced mixing…

Fluid Dynamics · Physics 2026-03-18 Enrico Turato , Christelle N. Prinz , Jason P. Beech , Jonas. O Tegenfeldt

Microfluidic mixing is a fundamental functionality in most lab on a chip (LOC) systems,whereas realization of efficient mixing is challenging in microfluidic channels due to the small Reynolds numbers. Here, we design and fabricate a…

Applied Physics · Physics 2020-01-10 Wenbo Li , Wei Chu , Peng Wang , Jia Qi , Zhe Wang , Jintian Lin , Min Wang , Ya Cheng

Generating droplets from a continuous stream of fluid requires precise tuning of a device to find optimized control parameter conditions. It is analytically intractable to compute the necessary control parameter values of a…

Machine Learning · Computer Science 2022-01-19 Alexander E. Siemenn , Evyatar Shaulsky , Matthew Beveridge , Tonio Buonassisi , Sara M. Hashmi , Iddo Drori

A phase--field method is applied to the modeling of flow and breakup of droplets in a T--shaped junction in the hydrodynamic regime where capillary and viscous stresses dominate over inertial forces, which is characteristic of microfluidic…

Soft Condensed Matter · Physics 2009-11-11 Mario De Menech