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In pathology, tissue samples are assessed using multiple staining techniques to enhance contrast in unique histologic features. In this paper, we introduce a multimodal CNN-GNN based graph fusion approach that leverages complementary…

Image and Video Processing · Electrical Eng. & Systems 2022-04-28 Chaitanya Dwivedi , Shima Nofallah , Maryam Pouryahya , Janani Iyer , Kenneth Leidal , Chuhan Chung , Timothy Watkins , Andrew Billin , Robert Myers , John Abel , Ali Behrooz

Tissue segmentation is an important pre-requisite for efficient and accurate diagnostics in digital pathology. However, it is well known that whole-slide scanners can fail in detecting all tissue regions, for example due to the tissue type,…

Computer Vision and Pattern Recognition · Computer Science 2017-04-04 Péter Bándi , Rob van de Loo , Milad Intezar , Daan Geijs , Francesco Ciompi , Bram van Ginneken , Jeroen van der Laak , Geert Litjens

There has been a steady increase in the incidence of skin cancer worldwide, with a high rate of mortality. Early detection and segmentation of skin lesions are crucial for timely diagnosis and treatment, necessary to improve the survival…

Computer Vision and Pattern Recognition · Computer Science 2019-12-04 Sulaiman Vesal , Nishant Ravikumar , Andreas Maier

Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Akash Modi , Sumit Kumar Jha , Purnendu Mishra , Rajiv Kumar , Kiran Aatre , Gursewak Singh , Shubham Mathur

Deep Learning has emerged as a promising approach for skin lesion analysis. However, existing methods mostly rely on fully supervised learning, requiring extensive labeled data, which is challenging and costly to obtain. To alleviate this…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Siyamalan Manivannan

Convolutional neural networks (CNNs) have achieved great success in skin lesion classification. A balanced dataset is required to train a good model. However, due to the appearance of different skin lesions in practice, severe or even…

Computer Vision and Pattern Recognition · Computer Science 2022-02-14 Keyu Chen , Di Zhuang , J. Morris Chang

Invariance learning methods aim to learn invariant features in the hope that they generalize under distributional shifts. Although many tasks are naturally characterized by continuous domains, current invariance learning techniques…

Machine Learning · Computer Science 2024-04-24 Yong Lin , Fan Zhou , Lu Tan , Lintao Ma , Jiameng Liu , Yansu He , Yuan Yuan , Yu Liu , James Zhang , Yujiu Yang , Hao Wang

Tumor spatial heterogeneity analysis requires precise correlation between Hematoxylin and Eosin H&E morphology and immunohistochemical (IHC) biomarker expression, yet current methods suffer from spatial misalignment in consecutive sections,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Yizhe Yuan , Bingsen Xue , Bangzheng Pu , Chengxiang Wang , Cheng Jin

Traditional steganalysis methods generally include two steps: feature extraction and classification.A variety of steganalysis algorithms based on CNN (Convolutional Neural Network) have appeared in recent years. Among them, the…

Cryptography and Security · Computer Science 2020-10-21 Ru Zhang , Sheng Zou , Jianyi Liu , Bingjie Lin , Dazhuang Liu

Variations in hematoxylin and eosin (H&E) stained images (due to clinical lab protocols, scanners, etc) directly impact the quality and accuracy of clinical diagnosis, and hence it is important to control for these variations for a reliable…

Image and Video Processing · Electrical Eng. & Systems 2020-06-26 Saad Nadeem , Travis Hollmann , Allen Tannenbaum

Segmentation of skin lesions is considered as an important step in computer aided diagnosis (CAD) for automated melanoma diagnosis. In recent years, segmentation methods based on fully convolutional networks (FCN) have achieved great…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Lei Bi , Dagan Feng , Jinman Kim

Background: The integration of multi-stain histopathology images through deep learning poses a significant challenge in digital histopathology. Current multi-modal approaches struggle with data heterogeneity and missing data. This study…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Valentin Koch , Sabine Bauer , Valerio Luppberger , Michael Joner , Heribert Schunkert , Julia A. Schnabel , Moritz von Scheidt , Carsten Marr

A key challenge in cancer immunotherapy biomarker research is quantification of pattern changes in microscopic whole slide images of tumor biopsies. Different cell types tend to migrate into various tissue compartments and form variable…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Amal Lahiani , Jacob Gildenblat , Irina Klaman , Nassir Navab , Eldad Klaiman

This paper proposes a sinogram consistency learning method to deal with beam-hardening related artifacts in polychromatic computerized tomography (CT). The presence of highly attenuating materials in the scan field causes an inconsistent…

Medical Physics · Physics 2019-06-06 Hyung Suk Park , Sung Min Lee , Hwa Pyung Kim , Jin Keun Seo

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

In this paper, we utilize deep visual Representation Learning to address an important problem in fashion e-commerce: color variants identification, i.e., identifying fashion products that match exactly in their design (or style), but only…

Computer Vision and Pattern Recognition · Computer Science 2021-07-02 Ujjal Kr Dutta , Sandeep Repakula , Maulik Parmar , Abhinav Ravi

Visual anomaly detection targets to detect images that notably differ from normal pattern, and it has found extensive application in identifying defective parts within the manufacturing industry. These anomaly detection paradigms…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Anindya Sundar Das , Guansong Pang , Monowar Bhuyan

Compared to hematoxylin-eosin (H&E) staining, immunohistochemistry (IHC) not only maintains the structural features of tissue samples, but also provides high-resolution protein localization, which is essential for aiding in pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Yuhang Kang , Ziyu Su , Tianyang Wang , Zaibo Li , Wei Chen , Muhammad Khalid Khan Niazi

Hematoxylin and eosin (H&E) staining visualizes histology but lacks specificity for diagnostic markers. Immunohistochemistry (IHC) staining provides protein-targeted staining but is restricted by tissue availability and antibody…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Anran Liu , Xiaofei Wang , Jing Cai , Chao Li

Hematoxylin and Eosin (H&E) staining is a widely used sample preparation procedure for enhancing the saturation of tissue sections and the contrast between nuclei and cytoplasm in histology images for medical diagnostics. However, various…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Fangda Li , Zhiqiang Hu , Wen Chen , Avinash Kak
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