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DNA-binding proteins (DBPs) are integral to gene regulation and cellular processes, making their accurate identification essential for understanding biological functions and disease mechanisms. Experimental methods for DBP identification…

Machine Learning · Computer Science 2025-07-29 Samiul Based Shuvo , Tasnia Binte Mamun , U Rajendra Acharya

Early diagnosis of melanoma, which can save thousands of lives, relies heavily on the analysis of dermoscopic images. One crucial diagnostic criterion is the identification of unusual pigment network (PN). However, distinguishing between…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 M. A. Rasel , Sameem Abdul Kareem , Unaizah Obaidellah

In recent years, the researches about solving partial differential equations (PDEs) based on artificial neural network have attracted considerable attention. In these researches, the neural network models are usually designed depend on…

Neural and Evolutionary Computing · Computer Science 2024-05-21 Bo Zhang , Chao Yang

Profiling core-periphery structures in networks has attracted significant attention, leading to the development of various methods. Among these, the rich-core method is distinguished for being entirely parameter-free and scalable to large…

Physics and Society · Physics 2025-04-17 Jiaqi Nie , Qi Xuan , Dehong Gao , Zhongyuan Ruan

Cluster-based descriptions of biological networks have received much attention in recent years fostered by accumulated evidence of the existence of meaningful correlations between topological network clusters and biological functional…

Molecular Networks · Quantitative Biology 2015-08-19 Ariel Berenstein , Janet Piñero , Laura Ines Furlong , Ariel Chernomoretz

This paper is concerned with distributed detection of central nodes in complex networks using closeness centrality. Closeness centrality plays an essential role in network analysis. Evaluating closeness centrality exactly requires complete…

Social and Information Networks · Computer Science 2021-06-29 Jordan F. Masakuna , Steve Kroon

In this study, we present a method of pattern mining based on network theory that enables the identification of protein structures or complexes from synthetic volume densities, without the knowledge of predefined templates or human biases…

Quantitative Methods · Quantitative Biology 2022-10-18 August George , Doo Nam Kim , Trevor Moser , Ian T. Gildea , James E. Evans , Margaret S. Cheung

Systematic identification of protein function is a key problem in current biology. Most traditional methods fail to identify functionally equivalent proteins if they lack similar sequences, structural data or extensive manual annotations.…

Genomics · Quantitative Biology 2016-03-08 Dan Ofer

Predicting interactions between biomolecules, such as protein-protein complexes, remains a challenging problem. Despite the many advancements done so far, the performances of docking protocols are deeply dependent on their capability of…

Biomolecules · Quantitative Biology 2025-08-19 Greta Grassmann , Lorenzo Di Rienzo , Giancarlo Ruocco , Mattia Miotto , Edoardo Milanetti

Composed of amino acid chains that influence how they fold and thus dictating their function and features, proteins are a class of macromolecules that play a central role in major biological processes and are required for the structure,…

Quantitative Methods · Quantitative Biology 2022-07-15 Aaron Wang

Background and Aim: Accurate classification of Magnetic Resonance Images (MRI) is essential to accurately predict Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) conversion. Meanwhile, deep learning has been successfully…

Computer Vision and Pattern Recognition · Computer Science 2021-09-03 Kshitiz Shrestha , Omar Hisham Alsadoon , Abeer Alsadoon , Tarik A. Rashid , Rasha S. Ali , P. W. C. Prasad , Oday D. Jerew

This research presents the development of an innovative algorithm tailored for the adaptive sampling of residual points within the framework of Physics-Informed Neural Networks (PINNs). By addressing the limitations inherent in existing…

Machine Learning · Computer Science 2023-06-16 Shikhar Nilabh , Fidel Grandia

We propose to learn a fully-convolutional network model that consists of a Chain of Identity Mapping Modules (CIMM) for image denoising. The CIMM structure possesses two distinctive features that are important for the noise removal task.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-22 Saeed Anwar , Cong Phouc Huynh , Fatih Porikli

Material identification is critical for understanding the relationship between mechanical properties and the associated mechanical functions. However, material identification is a challenging task, especially when the characteristic of the…

Materials Science · Physics 2022-11-29 Wensi Wu , Mitchell Daneker , Matthew A. Jolley , Kevin T. Turner , Lu Lu

As proteins with similar structures often have similar functions, analysis of protein structures can help predict protein functions and is thus important. We consider the problem of protein structure classification, which computationally…

Machine Learning · Statistics 2019-10-08 Hongyu Guo , Khalique Newaz , Scott Emrich , Tijana Milenkovic , Jun Li

Introduction: The extracellular matrix (ECM) is a networkof proteins and carbohydrates that has a structural and bio-chemical function. The ECM plays an important role in dif-ferentiation, migration and signaling. Several studies…

Quantitative Methods · Quantitative Biology 2022-02-17 Mohamed Ghafoor , Anh Nguyen

Pruning is an efficient model compression technique to remove redundancy in the connectivity of deep neural networks (DNNs). Computations using sparse matrices obtained by pruning parameters, however, exhibit vastly different parallelism…

Machine Learning · Computer Science 2019-05-15 Dongsoo Lee , Se Jung Kwon , Byeongwook Kim , Parichay Kapoor , Gu-Yeon Wei

Network representation learning (NRL) plays a vital role in a variety of tasks such as node classification and link prediction. It aims to learn low-dimensional vector representations for nodes based on network structures or node…

Social and Information Networks · Computer Science 2020-08-17 Ke Hou , Jiaying Liu , Yin Peng , Bo Xu , Ivan Lee , Feng Xia

In solving partial differential equations (PDEs), machine learning utilizing physical laws has received considerable attention owing to advantages such as mesh-free solutions, unsupervised learning, and feasibility for solving…

Machine Learning · Computer Science 2026-03-25 Tetsuro Tsuchino , Motoki Shiga

Analyzing networks requires complex algorithms to extract meaningful information. Centrality metrics have shown to be correlated with the importance and loads of the nodes in network traffic. Here, we are interested in the problem of…

Data Structures and Algorithms · Computer Science 2013-03-05 Ahmet Erdem Sariyuce , Kamer Kaya , Erik Saule , Umit V. Catalyurek
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