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Recent developments in multimodal large language models (MLLMs) have spurred significant interest in their potential applications across various medical imaging domains. On the one hand, there is a temptation to use these generative models…

Image and Video Processing · Electrical Eng. & Systems 2024-06-05 Sulaiman Khan , Md. Rafiul Biswas , Alina Murad , Hazrat Ali , Zubair Shah

Multimodal learning, especially large-scale multimodal pre-training, has developed rapidly over the past few years and led to the greatest advances in artificial intelligence (AI). Despite its effectiveness, understanding the underlying…

Neural and Evolutionary Computing · Computer Science 2022-08-18 Haoyu Lu , Qiongyi Zhou , Nanyi Fei , Zhiwu Lu , Mingyu Ding , Jingyuan Wen , Changde Du , Xin Zhao , Hao Sun , Huiguang He , Ji-Rong Wen

Current medical AI systems are often limited to narrow applications, hindering widespread adoption. We present MedVersa, a generalist foundation model trained on tens of millions of compiled medical instances. MedVersa unlocks generalist…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Hong-Yu Zhou , Julián Nicolás Acosta , Subathra Adithan , Suvrankar Datta , Eric J. Topol , Pranav Rajpurkar

Medical patient data is always multimodal. Images, text, age, gender, histopathological data are only few examples for different modalities in this context. Processing and integrating this multimodal data with deep learning based methods is…

Artificial Intelligence · Computer Science 2025-09-11 Christian Gapp , Elias Tappeiner , Martin Welk , Rainer Schubert

In medical contexts, the imbalanced data distribution in long-tailed datasets, due to scarce labels for rare diseases, greatly impairs the diagnostic accuracy of deep learning models. Recent multimodal text-image supervised foundation…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Sirui Li , Li Lin , Yijin Huang , Pujin Cheng , Xiaoying Tang

Many real-world tasks require an agent to reason jointly over text and visual objects, (e.g., navigating in public spaces), which we refer to as context-sensitive text-rich visual reasoning. Specifically, these tasks require an…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Rohan Wadhawan , Hritik Bansal , Kai-Wei Chang , Nanyun Peng

Foundation models have emerged as a powerful approach for processing electronic health records (EHRs), offering flexibility to handle diverse medical data modalities. In this study, we present a comprehensive benchmark that evaluates the…

Machine Learning · Computer Science 2025-07-22 Kunyu Yu , Rui Yang , Jingchi Liao , Siqi Li , Huitao Li , Irene Li , Yifan Peng , Rishikesan Kamaleswaran , Nan Liu

Multimodal foundation models aim to create a unified representation space that abstracts away from surface features like language syntax or modality differences. To investigate this, we study the internal representations of three recent…

Computation and Language · Computer Science 2025-02-21 Hyunji Lee , Danni Liu , Supriti Sinhamahapatra , Jan Niehues

This study investigated whether multimodal large language models can achieve human-like sensory grounding by examining their ability to capture perceptual strength ratings across sensory modalities. We explored how model characteristics…

Computation and Language · Computer Science 2025-11-10 Jonghyun Lee , Dojun Park , Jiwoo Lee , Hoekeon Choi , Sung-Eun Lee

Multimodal large language models have advanced rapidly, but their adoption in medicine is constrained by limited domain coverage, imperfect modality alignment, and insufficient grounded reasoning. We introduce MedMO, a medical multimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ankan Deria , Komal Kumar , Adinath Madhavrao Dukre , Eran Segal , Salman Khan , Imran Razzak

Background: Large language models (LLMs) are gaining use in clinical settings, but their performance can suffer with incomplete radiology reports. We tested whether multimodal LLMs (using text and images) could improve accuracy and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Choonghan Kim , Seonhee Cho , Joo Heung Yoon

Machine learning (ML) applications in medical artificial intelligence (AI) systems have shifted from traditional and statistical methods to increasing application of deep learning models. This survey navigates the current landscape of…

Machine Learning · Computer Science 2024-01-23 Elisa Warner , Joonsang Lee , William Hsu , Tanveer Syeda-Mahmood , Charles Kahn , Olivier Gevaert , Arvind Rao

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Recent advancements in deep learning have significantly revolutionized the field of clinical diagnosis and treatment, offering novel approaches to improve diagnostic precision and treatment efficacy across diverse clinical domains, thus…

Artificial Intelligence · Computer Science 2024-12-04 Kai Sun , Siyan Xue , Fuchun Sun , Haoran Sun , Yu Luo , Ling Wang , Siyuan Wang , Na Guo , Lei Liu , Tian Zhao , Xinzhou Wang , Lei Yang , Shuo Jin , Jun Yan , Jiahong Dong

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

Clinical decision-making relies on the integrated analysis of medical images and the associated clinical reports. While Vision-Language Models (VLMs) can offer a unified framework for such tasks, they can exhibit strong biases toward one…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 David Restrepo , Ira Ktena , Maria Vakalopoulou , Stergios Christodoulidis , Enzo Ferrante

Image-text matching is a key multimodal task that aims to model the semantic association between images and text as a matching relationship. With the advent of the multimedia information age, image, and text data show explosive growth, and…

Machine Learning · Computer Science 2024-06-24 Jinyin Wang , Haijing Zhang , Yihao Zhong , Yingbin Liang , Rongwei Ji , Yiru Cang

Positional bias - where models overemphasize certain positions regardless of content - has been shown to negatively impact model performance across various tasks. While recent research has extensively examined positional bias in text…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Kebin Wu , Fatima Albreiki

Retrieving visual and textual information from medical literature and hospital records can enhance diagnostic accuracy for clinical image interpretation. However, multimodal retrieval-augmented diagnosis is highly challenging. We explore a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nir Mazor , Tom Hope
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