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We introduce ICE-TIDE, a method for cryogenic electron tomography (cryo-ET) that simultaneously aligns observations and reconstructs a high-resolution volume. The alignment of tilt series in cryo-ET is a major problem limiting the…
3D dense reconstruction refers to the process of obtaining the complete shape and texture features of 3D objects from 2D planar images. 3D reconstruction is an important and extensively studied problem, but it is far from being solved. This…
Curvilinear structures frequently appear in microscopy imaging as the object of interest. Crystallographic defects, i.e., dislocations, are one of the curvilinear structures that have been repeatedly investigated under transmission electron…
Light-field microscopy (LFM) enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms. The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D fluorescence imaging,…
Deep learning has demonstrated superb efficacy in processing imaging data, yet its suitability in solving challenging inverse problems in scientific imaging has not been fully explored. Of immense interest is the determination of local…
Synchrotron-based X-ray computed tomography is widely used for investigating inner structures of specimens at high spatial resolutions. However, potential beam damage to samples often limits the X-ray exposure during tomography experiments.…
Dual-energy computed tomography (DECT) enables material-specific imaging through acquisitions at two different X-ray energy spectra. Material decomposition from DECT data is an ill-posed inverse problem that is highly sensitive to noise…
Multiple approaches to use deep learning for image restoration have recently been proposed. Training such approaches requires well registered pairs of high and low quality images. While this is easily achievable for many imaging modalities,…
This paper introduces a deep neural network based method, i.e., DeepOrganNet, to generate and visualize high-fidelity 3D / 4D organ geometric models from single-view medical image in real time. Traditional 3D / 4D medical image…
Cryogenic electron microscopy (cryo-EM) provides a unique opportunity to study the structural heterogeneity of biomolecules. Being able to explain this heterogeneity with atomic models would help our understanding of their functional…
Cryo-Electron Microscopy (Cryo-EM) is a Nobel prize-winning technology for determining the 3D structure of particles at near-atomic resolution. A fundamental step in the recovering of the 3D single-particle structure is to align its 2D…
This letter presents a novel hybrid method that leverages deep learning to exploit the multi-resolution analysis capability of the wavelets, in order to denoise a photoplethysmography (PPG) signal. Under the proposed method, a noisy PPG…
At X-ray beamlines of synchrotron light sources, the achievable time-resolution for 3D tomographic imaging of the interior of an object has been reduced to a fraction of a second, enabling rapidly changing structures to be examined. The…
Recovering textured 3D models of non-rigid human body shapes is challenging due to self-occlusions caused by complex body poses and shapes, clothing obstructions, lack of surface texture, background clutter, sparse set of cameras with…
Image denoising is a fundamental and challenging task in the field of computer vision. Most supervised denoising methods learn to reconstruct clean images from noisy inputs, which have intrinsic spectral bias and tend to produce…
We present a deep neural network to reduce coherent noise in three-dimensional quantitative phase imaging. Inspired by the cycle generative adversarial network, the denoising network was trained to learn a transform between two image…
Colloidoscope is a deep learning pipeline employing a 3D residual Unet architecture, designed to enhance the tracking of dense colloidal suspensions through confocal microscopy. This methodology uses a simulated training dataset that…
We present a novel approach for extracting 3D atomic-level information from transmission electron microscopy (TEM) images affected by significant noise. The approach is based on formulating depth estimation as a semantic segmentation…
Computed tomography has propelled scientific advances in fields from biology to materials science. This technology allows for the elucidation of 3-dimensional internal structure by the attenuation of x-rays through an object at different…
Electrocardiogram (ECG) signals are frequently corrupted by noise, such as baseline wander (BW), muscle artifacts (MA), and electrode motion (EM), which significantly degrade their diagnostic utility. To address this issue, we propose…