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Related papers: Disease Gene Prioritization With Quantum Walks

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Control and characterization of networks is a paramount step for the development of many quantum technologies. Even for moderate-sized networks, this amounts to explore an extremely vast parameters space in search for the couplings defining…

Quantum Physics · Physics 2024-05-30 Claudia Benedetti , Ilaria Gianani

Data mining techniques have been widely used to mine knowledgeable information from medical data bases. In data mining classification is a supervised learning that can be used to design models describing important data classes, where class…

Computers and Society · Computer Science 2015-08-11 M. A. Jabbar , B. L Deekshatulu , Priti Chandra

Quantum walks are at the heart of modern quantum technologies. They allow to deal with quantum transport phenomena and are an advanced tool for constructing novel quantum algorithms. Quantum walks on graphs are fundamentally different from…

Quantum Physics · Physics 2019-12-18 Alexey A. Melnikov , Leonid E. Fedichkin , Alexander Alodjants

Link prediction methods use patterns in known network data to infer which connections may be missing. Previous work has shown that continuous-time quantum walks can be used to represent path-based link prediction, which we further study…

Quantum Physics · Physics 2022-12-01 João P. Moutinho , Duarte Magano , Bruno Coutinho

A major challenge in biomedical data science is to identify the causal genes underlying complex genetic diseases. Despite the massive influx of genome sequencing data, identifying disease-relevant genes remains difficult as individuals with…

Genomics · Quantitative Biology 2020-01-20 Borislav H. Hristov , Bernard Chazelle , Mona Singh

Scientific and technological advances in medicine and systems biology have unequivocally shown that health and disease must be viewed in the context of the interplay among multiple molecular and environmental factors. Understanding the…

Aiming at the limitations of traditional medical decision system in processing large-scale heterogeneous medical data and realizing highly personalized recommendation, this paper introduces a personalized medical decision algorithm…

Machine Learning · Computer Science 2024-05-29 Yafeng Yan , Shuyao He , Zhou Yu , Jiajie Yuan , Ziang Liu , Yan Chen

Heart disease is a serious worldwide health issue because it claims the lives of many people who might have been treated if the disease had been identified earlier. The leading cause of death in the world is cardiovascular disease, usually…

Machine Learning · Computer Science 2024-09-10 Akua Sekyiwaa Osei-Nkwantabisa , Redeemer Ntumy

De novo DNA sequence assembly is based on finding paths in overlap graphs, which is a NP-hard problem. We developed a quantum algorithm for de novo assembly based on quantum walks in graphs. The overlap graph is partitioned repeatedly to…

Discovering disease pathways, which can be defined as sets of proteins associated with a given disease, is an important problem that has the potential to provide clinically actionable insights for disease diagnosis, prognosis, and…

Molecular Networks · Quantitative Biology 2017-12-05 Monica Agrawal , Marinka Zitnik , Jure Leskovec

The enormous successes have been made by quantum algorithms during the last decade. In this paper, we combine the quantum random walk (QRW) with the problem of data clustering, and develop two clustering algorithms based on the one…

Machine Learning · Computer Science 2008-12-09 Qiang Li , Yan He , Jing-ping Jiang

Identifying disease genes from human genome is an important and fundamental problem in biomedical research. Despite many publications of machine learning methods applied to discover new disease genes, it still remains a challenge because of…

Quantitative Methods · Quantitative Biology 2017-05-23 Peng Yang

The healthcare industry generates enormous amounts of complex clinical data that make the prediction of disease detection a complicated process. In medical informatics, making effective and efficient decisions is very important. Data Mining…

Machine Learning · Computer Science 2023-12-11 Alhaam Alariyibi , Mohamed El-Jarai , Abdelsalam Maatuk

Gene prioritization (identifying genes potentially associated with a biological process) is increasingly tackled with Artificial Intelligence. However, existing methods struggle with the high dimensionality and incomplete labelling of…

Parkinson's disease is a progressive and slowly developing neurodegenerative disease, characterized by dopaminergic neuron loss in the substantia nigra region of the brain. Despite extensive research by scientists, there is not yet a cure…

Quantitative Methods · Quantitative Biology 2024-08-31 Pratham Kankariya , Rachita Rode , Kevin Mudaliar , Pranali Hatode

Genetic algorithms are heuristic optimization techniques inspired by Darwinian evolution. Quantum computation is a new computational paradigm which exploits quantum resources to speed up information processing tasks. Therefore, it is…

Quantum Physics · Physics 2023-02-20 Rubén Ibarrondo , Giancarlo Gatti , Mikel Sanz

Hitting the exit node from the entrance node faster on a graph is one of the properties that quantum walk algorithms can take advantage of to outperform classical random walk algorithms. Especially, continuous-time quantum walks on…

Comparative analyses of protein-protein interaction networks play important roles in the understanding of biological processes. However, the growing enormity of available data on the networks becomes a computational challenge for the…

Computational Engineering, Finance, and Science · Computer Science 2016-04-15 Anmer Daskin

We present a probabilistic programmed deep kernel learning approach to personalized, predictive modeling of neurodegenerative diseases. Our analysis considers a spectrum of neural and symbolic machine learning approaches, which we assess…

Machine Learning · Computer Science 2021-01-13 Alexander Lavin

Genetic algorithms are heuristic optimization techniques inspired by Darwinian evolution, which are characterized by successfully finding robust solutions for optimization problems. Here, we propose a subroutine-based quantum genetic…

Quantum Physics · Physics 2024-06-07 Rubén Ibarrondo , Giancarlo Gatti , Mikel Sanz