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Low-intensity Transcranial Ultrasonic Stimulation (TUS) is a non-invasive brain stimulation technique enabling cortical and deep brain targeting with unprecedented spatial accuracy. Given the high rate of adoption by new users with varying…
As transcranial ultrasound stimulation (TUS) advances as a precise, non-invasive neuromodulatory method, there is a need for consistent reporting standards to enable comparison and reproducibility across studies. To this end, the…
Transcranial ultrasonic stimulation (TUS) has the potential to usher in a new era for human neuroscience by allowing spatially precise and high-resolution non-invasive targeting of both deep and superficial brain regions. Currently,…
Low-intensity transcranial focused ultrasound (tFUS) is rapidly emerging as a transformative non-invasive brain stimulation (NIBS) modality characterized by high spatial resolution and ability to target deep brain circuits. Unlike…
Transcranial ultrasonic stimulation (TUS) is rapidly gaining traction for non-invasive human neuromodulation, with a pressing need to establish protocols that maximise neuromodulatory efficacy. In this review, we aggregate and examine…
Transcranial magnetic stimulation (TMS) is a technique for noninvasively stimulating a brain area for therapeutic, rehabilitation treatments and neuroscience research. Despite our understanding of the physical principles and experimental…
Objective. While ultrasound is largely established for use in diagnostic imaging and heating therapies, its application for neuromodulation is relatively new and not well understood. The objective of the present study was to investigate…
Transcranial focused ultrasound (tFUS) is an emerging form of non-surgical human neuromodulation that confers advantages over existing electro and electromagnetic technologies by providing a superior spatial resolution on the millimeter…
Transcranial MRI-guided focused ultrasound (TcMRgFUS) thermal ablation is a noninvasive functional neurosurgery technique. Previous reports have shown that bone marrow damage in the skull can occur at high acoustic energies. While this…
Identifying what aspects of brain activity are responsible for conscious perception remains one of the most challenging problems in science. While progress has been made through psychophysical studies employing EEG and fMRI, research would…
In this article, we design a novel Transcranial Electrical Stimulator for medical applications, which is very cheap and can produce the desired signals very accurately. Our fabricated stimulator generates all current signals related to…
Background: Individual skull models of bone density and geometry are important when planning the expected transcranial ultrasound acoustic field and estimating mechanical and thermal safety in low-intensity transcranial ultrasound…
Transcranial photobiomodulation is an optical method for non-invasive brain stimulation. The method projects red and near-infrared light through the scalp within 600-1100 nm and low energy within the 1-20 J/cm2 range. Recent studies have…
For decades, focal non-invasive neuromodulation of deep brain regions has not been possible because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic…
Background: Trans-spinal FUS (tsFUS) has recently been shown promise in modulating spinal reflexes in rodents, opening new avenues for spinal cord interventions in motor control and pain management. However, anatomical differences between…
Focused ultrasound spinal cord neuromodulation studies have demonstrated spinal cord neuromodulation in small animals. The safe and efficacious translation of these approaches to human scale requires an understanding of ultrasound…
Transcranial ultrasound (TUS) has emerged as a promising tool in clinical and research settings due to its potential to modulate neuronal activity, open the blood-brain barrier, facilitate targeted drug delivery via nanoparticles, and…
This work explored an element-wise approach to model transcranial MRI-guided focused ultrasound (TcMRgFUS) thermal ablation, a noninvasive approach to neurosurgery. Each element of the phased array transducer was simulated individually and…
Background: The use of near-infrared lasers for transcranial photobiomodulation (tPBM) offers a non-invasive method for influencing brain activity and is beneficial for various neurological conditions. Objective: To investigate the safety…
The main objective of the electrical stimulation of the brain is to generate action potentials from the application of electromagnetic fields. Among the available techniques, transcranial electrical stimulation (TES) represents a popular…