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We present a method for efficient differentiable simulation of articulated bodies. This enables integration of articulated body dynamics into deep learning frameworks, and gradient-based optimization of neural networks that operate on…

Machine Learning · Computer Science 2021-09-17 Yi-Ling Qiao , Junbang Liang , Vladlen Koltun , Ming C. Lin

Recent breakthroughs in artificial intelligence (AI) are reshaping the way we construct computational counterparts of the brain, giving rise to a new class of ``surrogate brains''. In contrast to conventional hypothesis-driven biophysical…

Neurons and Cognition · Quantitative Biology 2025-10-14 Yinuo Zhang , Demao Liu , Zhichao Liang , Jiani Cheng , Kexin Lou , Jinqiao Duan , Ting Gao , Bin Hu , Quanying Liu

Solving large dense linear systems and eigenvalue problems is a core requirement in many areas of scientific computing, but scaling these operations beyond a single GPU remains challenging within modern programming frameworks. While highly…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-22 Roeland Wiersema

Modern deep neural networks increasingly make use of features such as dynamic control flow, data structures and dynamic tensor shapes. Existing deep learning systems focus on optimizing and executing static neural networks which assume a…

Programming Languages · Computer Science 2021-03-15 Haichen Shen , Jared Roesch , Zhi Chen , Wei Chen , Yong Wu , Mu Li , Vin Sharma , Zachary Tatlock , Yida Wang

Artificial Intelligence (AI) systems based solely on neural networks or symbolic computation present a representational complexity challenge. While minimal representations can produce behavioral outputs like locomotion or simple…

Neurons and Cognition · Quantitative Biology 2022-10-19 Bradly Alicea , Jesse Parent

This perspective analyzes the intricate interplay among neuroscience, Brain-Inspired Intelligence (BII), and Brain-Inspired Navigation (BIN), revealing a current lack of cooperative relationship between Brain-Computer Interfaces (BCIs) and…

Emerging Technologies · Computer Science 2025-10-21 Xu He , Xiaolin Meng , Youdong Zhang , Lingfei Mo , Wenxuan Yin

Limitations in processing capabilities and memory of today's computers make spiking neuron-based (human) whole-brain simulations inevitably characterized by a compromise between bio-plausibility and computational cost. It translates into…

Neurons and Cognition · Quantitative Biology 2020-07-17 Gianluca Susi , Pilar Garces , Alessandro Cristini , Emanuele Paracone , Mario Salerno , Fernando Maestu , Ernesto Pereda

Biologically-informed neural networks (BINNs), an extension of physics-informed neural networks [1], are introduced and used to discover the underlying dynamics of biological systems from sparse experimental data. In the present work, BINNs…

Quantitative Methods · Quantitative Biology 2021-01-27 John H. Lagergren , John T. Nardini , Ruth E. Baker , Matthew J. Simpson , Kevin B. Flores

BrainLesion Suite is a versatile toolkit for building modular brain lesion image analysis pipelines in Python. Following Pythonic principles, BrainLesion Suite is designed to provide a 'brainless' development experience, minimizing…

Models capable of "thinking with images" by dynamically grounding their reasoning in visual evidence represent a major leap in multimodal AI. However, replicating and advancing this ability is non-trivial, with current methods often trapped…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Zhaoyang Wei , Wenchao Ding , Yanchao Hao , Xi Chen

User simulation is important for developing and evaluating human-centered AI, yet current student simulation in educational applications has significant limitations. Existing approaches focus on single learning experiences and do not…

Computers and Society · Computer Science 2026-01-27 Zhengyuan Liu , Stella Xin Yin , Bryan Chen Zhengyu Tan , Roy Ka-Wei Lee , Guimei Liu , Dion Hoe-Lian Goh , Wenya Wang , Nancy F. Chen

We introduce BriLLM, a brain-inspired large language model that fundamentally redefines the foundations of machine learning through its implementation of Signal Fully-connected flowing (SiFu) learning. This work addresses the critical…

Computation and Language · Computer Science 2025-09-09 Hai Zhao , Hongqiu Wu , Dongjie Yang , Anni Zou , Jiale Hong

In this work, we present HiAER-Spike, a modular, reconfigurable, event-driven neuromorphic computing platform designed to execute large spiking neural networks with up to 160 million neurons and 40 billion synapses - roughly twice the…

Pipeline parallelism is a crucial paradigm for large-scale model training. However, imbalances in memory footprint across stages can lead to significant GPU memory wastage, limiting the model sizes that pipeline parallelism can effectively…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-12 Xuan Peng , Xuanhua Shi , Haolin Zhang , Yunfei Zhao , Xuehai Qian

Simulation plays a central role in scientific discovery. In many applications, the bottleneck is no longer running a simulator; it is choosing among large families of plausible simulators, each corresponding to different forward…

One of the fundamental tasks in machine learning is image classification, which serves as a key benchmark for validating algorithm performance and practical potential. However, effectively processing high-dimensional, detail-rich images, a…

Quantum Physics · Physics 2025-09-09 Chenghua Duan , Xiuxing Li , Wending Zhao , Lin Yao , Qing Li , Ziyu Li , Fukang Li , Junhao Ma , Xia Wu

What is it about human brains that allows us to reason symbolically whereas most other animals cannot? There is evidence that dynamic binding, the ability to combine neurons into groups on the fly, is necessary for symbolic thought, but…

Neural and Evolutionary Computing · Computer Science 2025-08-22 John E. Hummel , Rachel F. Heaton

Human intelligence emerged through the process of natural selection and evolution on Earth. We investigate what it would take to re-create this process in silico. While past work has often focused on low-level processes (such as simulating…

Artificial Intelligence · Computer Science 2024-09-04 Chris Lu , Michael Beukman , Michael Matthews , Jakob Foerster

Neuromorphic systems open up opportunities to enlarge the explorative space for computational research. However, it is often challenging to unite efficiency and usability. This work presents the software aspects of this endeavor for the…

The massively parallel nature of biological information processing plays an important role for its superiority to human-engineered computing devices. In particular, it may hold the key to overcoming the von Neumann bottleneck that limits…