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The opioid epidemic is a crisis that has plagued the United States (US) for decades. One central issue is inequitable access to treatment for opioid use disorder (OUD), which puts certain populations at a higher risk of opioid overdose. We…

Physics and Society · Physics 2024-03-14 Joyce Luo , Bartolomeo Stellato

Opioid Use Disorder (OUD) has reached an epidemic level in the US. Diversion of unused prescription opioids to secondary users and black market significantly contributes to the abuse and misuse of these highly addictive drugs, leading to…

Optimization and Control · Mathematics 2022-10-17 Md Mahmudul Hasan , Tasnim Ibn Faiz , Alicia Sasser Modestino , Gary J. Young , Md. Noor-E-Alam

The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in…

Quantitative Methods · Quantitative Biology 2019-05-03 Jen J. Gong , Abigail Z. Jacobs , Toby E. Stuart , Mathijs de Vaan

Opioid overdose has emerged as a full blown epidemic in the United States. In the last few years, there has been an alarming increase in Opioid related deaths, resulting in the loss of 63,600 lives in 2016 alone. The epidemic which is…

Computers and Society · Computer Science 2018-05-16 Kaustav Basu , Sandipan Choudhuri , Arunabha Sen , Aniket Majumdar

Drug overdose deaths, including from opioids, remain a significant public health threat to the United States (US). To abate the harms of opioid misuse, understanding its prevalence at the local level is crucial for stakeholders in…

Applications · Statistics 2026-01-09 Zixuan Feng , Qiushi Chen , Paul Griffin , Le Bao

Substance Use Disorders (SUDs) involve the misuse of any or several of a wide array of substances, such as alcohol, opioids, marijuana, and methamphetamine. SUDs are characterized by an inability to decrease use despite severe social,…

Computers and Society · Computer Science 2020-06-25 Lana Yarosh , Suzanne Bakken , Alan Borning , Munmun De Choudhury , Cliff Lampe , Elizabeth Mynatt , Stephen Schueller , Tiffany Veinot

Opioid overdose rates have reached an epidemic level and state-level policy innovations have followed suit in an effort to prevent overdose deaths. State-level drug law is a set of policies that may reinforce or undermine each other, and…

Applications · Statistics 2020-10-07 Jarrod Olson , Po-Hsu Allen Chen , Marissa White , Nicole Brennan , Ning Gong

Overdose related to prescription opioids have reached an epidemic level in the US, creating an unprecedented national crisis. This has been exacerbated partly due to the lack of tools for physicians to help predict the risk of whether a…

In the last decade, the United States has lost more than 500,000 people from an overdose involving prescription and illicit opioids making it a national public health emergency (USDHHS, 2017). Medical practitioners require robust and timely…

Computation and Language · Computer Science 2024-06-17 Chenghao Yang , Tuhin Chakrabarty , Karli R Hochstatter , Melissa N Slavin , Nabila El-Bassel , Smaranda Muresan

The United States is currently experiencing an unprecedented opioid crisis, and opioid overdose has become a leading cause of injury and death. Effective opioid addiction recovery calls for not only medical treatments, but also behavioral…

Social and Information Networks · Computer Science 2019-12-04 Zhou Yang , Spencer Bradshaw , Rattikorn Hewett , Fang Jin

Opioid addiction has become a global epidemic and a national health crisis in recent years, with the number of opioid overdose fatalities steadily increasing since the 1990s. In contrast to the dynamics of a typical illicit drug or disease…

Populations and Evolution · Quantitative Biology 2019-05-03 Nicholas A. Battista , Leigh B. Pearcy , W. Christopher Strickland

According to the Center of Disease Control (CDC), the Opioid epidemic has claimed more than 72,000 lives in the US in 2017 alone. In spite of various efforts at the local, state and federal level, the impact of the epidemic is becoming…

Computer Vision and Pattern Recognition · Computer Science 2019-06-24 Sandipan Choudhuri , Kaustav Basu , Kevin Thomas , Arunabha Sen

The United States is experiencing an opioid epidemic, and there were more than 10 million opioid misusers aged 12 or older each year. Identifying patients at high risk of Opioid Use Disorder (OUD) can help to make early clinical…

We present a nation-wide network analysis of non-fatal opioid-involved overdose journeys in the United States. Leveraging a unique proprietary dataset of Emergency Medical Services incidents, we construct a journey-to-overdose geospatial…

Social and Information Networks · Computer Science 2024-08-06 Lucas H. McCabe , Naoki Masuda , Shannon Casillas , Nathan Danneman , Alen Alic , Royal Law

Opioid overdose is a growing public health crisis in the United States. This crisis, recognized as "opioid epidemic," has widespread societal consequences including the degradation of health, and the increase in crime rates and family…

Machine Learning · Computer Science 2020-06-01 Ali Mert Ertugrul , Yu-Ru Lin , Tugba Taskaya-Temizel

The drug overdose crisis in the United States continues to intensify. Fatalities have increased five-fold since 1999 reaching a record high of 108,000 deaths in 2021. The epidemic has unfolded through distinct waves of different drug types,…

Applications · Statistics 2023-09-27 Lucas Böttcher , Tom Chou , Maria R. D'Orsogna

The opioid crisis remains one of the most daunting and complex public health problems in the United States. This study investigates the national epidemic by analyzing vulnerability profiles of three key factors: opioid-related mortality…

The opioid epidemic remains one of the most severe public health crises in the United States, yet evaluating policy interventions before implementation is difficult: multiple policies interact within a dynamic system where targeting one…

Machine Learning · Computer Science 2026-02-16 Yijun Ma , Zehong Wang , Weixiang Sun , Zheyuan Zhang , Kaiwen Shi , Nitesh Chawla , Yanfang Ye

The opioid crisis remains a critical public health challenge in the United States. Despite national efforts which reduced opioid prescribing rates by nearly 45\% between 2011 and 2021, opioid-related overdose deaths more than tripled during…

Computers and Society · Computer Science 2025-08-20 Andrew Deas , Adam Spannaus , Dakotah D. Maguire , Jodie Trafton , Anuj J. Kapadia , Vasileios Maroulas

Introduction: Chronic pain patients are at increased risk of opioid-misuse. Less is known about the unique risk conferred by each pain-management treatment, as treatments are typically implemented together, confounding their independent…

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