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Agent-based modeling (ABM) is a powerful computational approach for studying complex biological and biomedical systems, yet its widespread use remains limited by significant computational demands. As models become increasingly…

Quantitative Methods · Quantitative Biology 2025-04-17 Kerri-Ann Norton , Daniel Bergman , Harsh Vardhan Jain , Trachette Jackson

Physics-Informed Neural Networks (PINNs) have emerged as a powerful tool for solving partial differential equations~(PDEs) in various scientific and engineering domains. However, traditional PINN architectures typically rely on large, fully…

Computational Engineering, Finance, and Science · Computer Science 2024-04-22 Stefano Markidis

Compartmental models provide simple and efficient tools to analyze the relevant transmission processes during an outbreak, to produce short-term forecasts or transmission scenarios, and to assess the impact of vaccination campaigns.…

Numerical Analysis · Mathematics 2025-02-19 Caterina Millevoi , Damiano Pasetto , Massimiliano Ferronato

An agent-based model (ABM) is a computational model in which the local interactions of autonomous agents with each other and with their environment give rise to global properties within a given domain. As the detail and complexity of these…

Dynamical Systems · Mathematics 2022-12-01 Daniel A. Cruz , Jack Toppen , Eunbi Park , Melissa L. Kemp , Elena S. Dimitrova

In this research, the application of the Physics-Informed Neural Network (PINN) model is explored to solve transport equation-based Partial Differential Equations (PDEs). The primary objective is to analyze the impact of different…

Machine Learning · Computer Science 2023-12-04 Akshansh Mishra

Modeling tumor growth accurately is essential for understanding cancer progression and informing treatment strategies. To estimate the parameters in the tumor growth model described by a nonlinear PDE, we adopt Physics-Informed Neural…

Analysis of PDEs · Mathematics 2025-11-21 Liu Liu , Yifei Wang , Qinyu Xu , Xiaoqian Xu

Structural failures are often caused by catastrophic events such as earthquakes and winds. As a result, it is crucial to predict dynamic stress distributions during highly disruptive events in real time. Currently available high-fidelity…

Machine Learning · Computer Science 2022-11-30 Hamed Bolandi , Gautam Sreekumar , Xuyang Li , Nizar Lajnef , Vishnu Naresh Boddeti

Reliable spacecraft attitude control depends on accurate prediction of attitude dynamics, particularly when model-based strategies such as Model Predictive Control (MPC) are employed, where performance is limited by the quality of the…

Robotics · Computer Science 2026-02-19 Carlo Cena , Mauro Martini , Marcello Chiaberge

Physics-informed neural networks (PINNs) have emerged as a promising approach to solving partial differential equations (PDEs) using neural networks, particularly in data-scarce scenarios, due to their unsupervised training capability.…

Machine Learning · Computer Science 2025-03-25 Edgar Torres , Jonathan Schiefer , Mathias Niepert

Physics-informed neural networks (PINNs) and their variants have been very popular in recent years as algorithms for the numerical simulation of both forward and inverse problems for partial differential equations. This article aims to…

Numerical Analysis · Mathematics 2024-11-20 Tim De Ryck , Siddhartha Mishra

Accurate forecasting of contagious diseases is critical for public health policymaking and pandemic preparedness. We propose a new infectious disease forecasting model based on physics-informed neural networks (PINNs), an emerging…

Machine Learning · Computer Science 2025-04-30 Ying Qian , Kui Zhang , Éric Marty , Avranil Basu , Eamon B. O'Dea , Xianqiao Wang , Spencer Fox , Pejman Rohani , John M. Drake , He Li

Predicting the infiltration of Glioblastoma (GBM) from medical MRI scans is crucial for understanding tumor growth dynamics and designing personalized radiotherapy treatment plans.Mathematical models of GBM growth can complement the data in…

Machine Learning · Computer Science 2024-08-19 Ray Zirui Zhang , Ivan Ezhov , Michal Balcerak , Andy Zhu , Benedikt Wiestler , Bjoern Menze , John S. Lowengrub

Recently, physics informed neural networks (PINNs) have been explored extensively for solving various forward and inverse problems and facilitating querying applications in fluid mechanics applications. However, work on PINNs for unsteady…

Fluid Dynamics · Physics 2024-02-28 Rahul Sundar , Dipanjan Majumdar , Didier Lucor , Sunetra Sarkar

We introduce a machine-learning framework named statistics-informed neural network (SINN) for learning stochastic dynamics from data. This new architecture was theoretically inspired by a universal approximation theorem for stochastic…

Machine Learning · Computer Science 2022-12-28 Yuanran Zhu , Yu-Hang Tang , Changho Kim

Deep learning has emerged as a powerful tool in scientific modeling, particularly for complex dynamical systems; however, accurately capturing age-structured population dynamics under policy-driven fertility changes remains a significant…

Machine Learning · Computer Science 2025-05-06 Ze Tao

Many real-world processes can naturally be modeled as systems of interacting agents. However, the long-term simulation of such agent-based models is often intractable when the system becomes too large. In this paper, starting from a…

Wire-arc directed energy deposition (DED) has emerged as a promising additive manufacturing (AM) technology for large-scale structural engineering applications. However, the complex thermal dynamics inherent to the process present…

Computational Engineering, Finance, and Science · Computer Science 2025-07-15 Michael Ryan , Mohammad Hassan Baqershahi , Hessamoddin Moshayedi , Elyas Ghafoori

Integrating theoretical neuroscience, decision theory, and probabilistic inference offers a promising route to understanding human cognition, yet concrete methodological bridges between agentic AI models and behavioral data analysis remain…

Neurons and Cognition · Quantitative Biology 2026-05-01 Dirk Ostwald , Rasmus Bruckner , Franziska Usée , Belinda Fleischmann , Joram Soch , Sean Mulready

Physics-Informed Neural Networks (PINN) are neural networks (NNs) that encode model equations, like Partial Differential Equations (PDE), as a component of the neural network itself. PINNs are nowadays used to solve PDEs, fractional…

An important inference from Neural Tangent Kernel (NTK) theory is the existence of spectral bias (SB), that is, low frequency components of the target function of a fully connected Artificial Neural Network (ANN) being learnt significantly…

Machine Learning · Computer Science 2023-01-10 Mayank Deshpande , Siddharth Agarwal , Vukka Snigdha , Arya Kumar Bhattacharya