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Quantum algorithms on near-term quantum processors are typically executed using shallow quantum circuits composed of one- and two-qubit gates. However, as circuit depth and gate number increase, gate imperfections and qubit decoherence…

We study a hardware-efficient variational quantum algorithm ansatz tailored for the trapped-ion quantum simulator, HEA-TI. We leverage programmable single-qubit rotations and global spin-spin interactions among all ions, reducing the…

Quantum Physics · Physics 2024-07-04 J. -Z. Zhuang , Y. -K. Wu , L. -M. Duan

Unitary operations are the building blocks of quantum programs. Our task is to design effcient or optimal implementations of these unitary operations by employing the intrinsic physical resources of a given n-qubit system. The most common…

Quantum Physics · Physics 2007-05-23 Robert Zeier , Markus Grassl , Thomas Beth

Topological quantum computing has recently proven itself to be a very powerful model when considering large- scale, fully error corrected quantum architectures. In addition to its robust nature under hardware errors, it is a software driven…

Quantum Physics · Physics 2016-11-17 Alexandru Paler , Simon J. Devitt , Kae Nemoto , Ilia Polian

Many researches have been working on the protein folding problem from more than half century. Protein folding is indeed one of the major unsolved problems in science. In this work, we discuss a model for the simulation of protein…

Optimization and Control · Mathematics 2008-11-20 A. Mucherino , O. Seref , P. M. Pardalos

Quantum chemistry and materials science are among the most promising areas for demonstrating algorithmic quantum advantage and quantum utility due to their inherent quantum mechanical nature. Still, large-scale simulations of quantum…

Simulating noninteracting fermion systems is a common task in computational many-body physics. In absence of translational symmetries, modeling free fermions on $N$ modes usually requires poly$(N)$ computational resources. While often…

Quantum Physics · Physics 2026-02-24 Maarten Stroeks , Daan Lenterman , Barbara Terhal , Yaroslav Herasymenko

Molecular biology and biochemistry interpret microscopic processes in the living world in terms of molecular structures and their interactions, which are quantum mechanical by their very nature. Whereas the theoretical foundations of these…

Quantum Physics · Physics 2023-07-07 Alberto Baiardi , Matthias Christandl , Markus Reiher

The advent of quantum computing processors with possibility to scale beyond experimental capacities magnifies the importance of studying their applications. Combinatorial optimization problems can be one of the promising applications of…

Quantum Physics · Physics 2017-08-18 Ehsan Zahedinejad , Arman Zaribafiyan

Quantum computing promises the ability to compute properties of quantum systems exponentially faster than classical computers. Quantum advantage is achieved when a practical problem is solved more efficiently on a quantum computer than on a…

Quantum Physics · Physics 2025-12-03 William A. Simon , Peter J. Love

Accurate prediction of protein active-site structures remains a central challenge in structural biology, particularly for short and flexible peptide fragments where conventional and simulation-based methods often fail. Here, we present a…

Quantum computation appears to offer significant advantages over classical computation and this has generated a tremendous interest in the field. In this thesis we consider the application of quantum computers to scientific computing and…

Quantum Physics · Physics 2018-05-10 Stuart Hadfield

We define some of the programming and system-level challenges facing the application of quantum processing to high-performance computing. Alongside barriers to physical integration, prominent differences in the execution of quantum and…

Quantum Physics · Physics 2017-12-06 Keith A. Britt , Fahd A. Mohiyaddin , Travis S. Humble

Accurate simulation of dynamical processes in molecules and reactions is among the most challenging problems in quantum chemistry. Quantum computers promise efficient chemical simulation, but the existing quantum algorithms require many…

We present a quantum algorithm for the simulation of molecular systems that is asymptotically more efficient than all previous algorithms in the literature in terms of the main problem parameters. As in previous work [Babbush et al., New…

A quantum computer consists of a set of quantum bits upon which operations called gates are applied to perform computations. In order to perform quantum algorithms, physicists would like to design arbitrary gates to apply to quantum bits.…

Quantum Physics · Physics 2012-06-18 Jeffrey Booth

We provide practical simulation methods for scalar field theories on a quantum computer that yield improved asymptotics as well as concrete gate estimates for the simulation and physical qubit estimates using the surface code. We achieve…

Quantum computing has the potential to revolutionize multiple fields by solving complex problems that can not be solved in reasonable time with current classical computers. Nevertheless, the development of quantum computers is still in its…

Quantum computing has brought a paradigm change in computer science, where non-classical technologies have promised to outperform their classical counterpart. Such an advantage was only demonstrated for tasks without practical applications,…

Major obstacles remain to the implementation of macroscopic quantum computing: hardware problems of noise, decoherence, and scaling; software problems of error correction; and, most important, algorithm construction. Finding truly quantum…

Quantum Physics · Physics 2020-07-17 Nathan Thompson , James Steck , Elizabeth Behrman
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