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Often in follow-up studies intermediate events occur in some patients, such as reinterventions or adverse events. These intermediate events directly affect the shapes of their longitudinal profiles. Our work is motivated by two studies in…

Based on the proposed time-varying JLCM (Miao and Charalambous, 2022), the heterogeneous random covariance matrix can also be considered, and a regression submodel for the variance-covariance matrix of the multivariate latent random effects…

Methodology · Statistics 2025-03-30 Ruoyu Miao , Christiana Charalambous

Joint latent class modelling has been developed considerably in the past two decades. In some instances, the models are linked by the latent class k (i.e. the number of subgroups), in others they are joined by shared random effects or a…

Methodology · Statistics 2023-03-02 Ruoyu Miao , Christiana Charalambous

Behavior prediction based on historical behavioral data have practical real-world significance. It has been applied in recommendation, predicting academic performance, etc. With the refinement of user data description, the development of…

Machine Learning · Computer Science 2023-09-27 Haobing Liu , Yanmin Zhu , Chunyang Wang , Jianyu Ding , Jiadi Yu , Feilong Tang

This paper introduces a prognostic method called FLASH that addresses the problem of joint modelling of longitudinal data and censored durations when a large number of both longitudinal and time-independent features are available. In the…

Joint models for longitudinal and survival data have become a popular framework for studying the association between repeatedly measured biomarkers and clinical events. Nevertheless, addressing complex survival data structures, especially…

A key question in clinical practice is accurate prediction of patient prognosis. To this end, nowadays, physicians have at their disposal a variety of tests and biomarkers to aid them in optimizing medical care. These tests are often…

We introduce a numerically tractable formulation of Bayesian joint models for longitudinal and survival data. The longitudinal process is modelled using generalised linear mixed models, while the survival process is modelled using a…

Methodology · Statistics 2021-04-23 Danilo Alvares , Francisco Javier Rubio

In medical and biological research, longitudinal data and survival data types are commonly seen. Traditional statistical models mostly consider to deal with either of the data types, such as linear mixed models for longitudinal data, and…

Methodology · Statistics 2021-07-12 Jizi Shangguan

In many clinical and epidemiological studies, collecting longitudinal measurements together with time-to-event outcomes is essential. Accurately estimating the association between longitudinal markers and event risks, as well as identifying…

In the field of cardio-thoracic surgery, valve function is monitored over time after surgery. The motivation for our research comes from a study which includes patients who received a human tissue valve in the aortic position. These…

In a real-life setting, little is known regarding the effectiveness of statins for primary prevention among older adults, and analysis of observational data can add crucial information on the benefits of actual patterns of use. Latent class…

Methodology · Statistics 2023-10-18 Awa Diop , Caroline Sirois , Jason Robert Guertin , Denis Talbot

Joint models initially dedicated to a single longitudinal marker and a single time-to-event need to be extended to account for the rich longitudinal data of cohort studies. Multiple causes of clinical progression are indeed usually…

Applications · Statistics 2016-01-26 Cécile Proust-Lima , Jean-François Dartigues , Hélène Jacqmin-Gadda

Dynamical phenomena such as infectious diseases are often investigated by following up subjects longitudinally, thus generating time to event data. The spatial aspect of such data is also of primordial importance, as many infectious…

Methodology · Statistics 2020-10-13 Ajmal Oodally , Estelle Kuhn , Klara Goethals , Luc Duchateau

Joint multivariate longitudinal and time-to-event data are gaining increasing attention in the biomedical sciences where subjects are followed over time to monitor the progress of a disease or medical condition. In the insurance context,…

Methodology · Statistics 2019-02-12 Edward W. Frees , Catalina Bolancé , Montserrat Guillen , Emiliano Valdez

We introduce a Bayesian approach for analyzing high-dimensional multinomial data that are referenced over space and time. In particular, the proportions associated with multinomial data are assumed to have a logit link to a latent…

Methodology · Statistics 2018-12-11 Jonathan R. Bradley , Christopher K. Wikle , Scott H. Holan

Traffic prediction has gradually attracted the attention of researchers because of the increase in traffic big data. Therefore, how to mine the complex spatio-temporal correlations in traffic data to predict traffic conditions more…

Machine Learning · Computer Science 2021-12-07 Yuchen Fang , Yanjun Qin , Haiyong Luo , Fang Zhao , Chenxing Wang

Joint modeling has become increasingly popular for characterizing the association between one or more longitudinal biomarkers and competing risks time-to-event outcomes. However, semiparametric multivariate joint modeling for large-scale…

Methodology · Statistics 2025-06-17 Shanpeng Li , Emily Ouyang , Jin Zhou , Xinping Cui , Gang Li

The objective is to model longitudinal and survival data jointly taking into account the dependence between the two responses in a real HIV/AIDS dataset using a shared parameter approach inside a Bayesian framework. We propose a linear…

Applications · Statistics 2016-05-02 Rui Martins

Time-varying covariates in longitudinal studies frequently evolve through reciprocal feedback, undergo role reversal, and reflect unobserved individual heterogeneity. Standard statistical frameworks often assume fixed covariate roles and…

Methodology · Statistics 2026-02-27 Niloofar Ramezani , Pascal Nitiema , Jeffrey R. Wilson