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Optimizing the mRNA codon has an essential impact on gene expression for a specific target protein. It is an NP-hard problem; thus, exact solutions to such optimization problems become computationally intractable for realistic problem sizes…

Quantum Physics · Physics 2024-05-13 Hongfeng Zhang , Aritra Sarkar , Koen Bertels

We develop and implement automated methods for optimizing quantum circuits of the size and type expected in quantum computations that outperform classical computers. We show how to handle continuous gate parameters and report a collection…

Quantum Physics · Physics 2018-06-04 Yunseong Nam , Neil J. Ross , Yuan Su , Andrew M. Childs , Dmitri Maslov

We present a quantum algorithmic routine that extends the realm of Grover-based heuristics for tackling combinatorial optimization problems with arbitrary efficiently computable objective and constraint functions. Building on previously…

Quantum Physics · Physics 2025-12-10 Sören Wilkening

Variational quantum algorithms are believed to be promising for solving computationally hard problems and are often comprised of repeated layers of quantum gates. An example thereof is the quantum approximate optimization algorithm (QAOA),…

Benson's outer approximation algorithm and its variants are the most frequently used methods for solving linear multiobjective optimization problems. These algorithms have two intertwined components: one-dimensional linear optimization one…

Optimization and Control · Mathematics 2019-03-21 Laszlo Csirmaz

Quantum algorithm design usually assumes access to a perfect quantum computer with ideal properties like full connectivity, noise-freedom and arbitrarily long coherence time. In Noisy Intermediate-Scale Quantum (NISQ) devices, however, the…

Quantum Physics · Physics 2020-09-11 Xiangzhen Zhou , Sanjiang Li , Yuan Feng

We present a quantum interior point method with worst case running time $\widetilde{O}(\frac{n^{2.5}}{\xi^{2}} \mu \kappa^3 \log (1/\epsilon))$ for SDPs and $\widetilde{O}(\frac{n^{1.5}}{\xi^{2}} \mu \kappa^3 \log (1/\epsilon))$ for LPs,…

Quantum Physics · Physics 2018-08-29 Iordanis Kerenidis , Anupam Prakash

We study quantum algorithms for approximating Lasserre's hierarchy values for polynomial optimization. Let $f,g_1,\ldots,g_m$ be real polynomials in $n$ variables and $f^\star$ the infimum of $f$ over the semialgebraic set $S(g)=\{x:…

Quantum Physics · Physics 2025-11-19 Daniel Stilck França , Ngoc Hoang Anh Mai

Quantum circuit mapping is a critical process in quantum computing that involves adapting logical quantum circuits to adhere to hardware constraints, thereby generating physically executable quantum circuits. Current quantum circuit mapping…

Quantum Physics · Physics 2025-07-08 Wenjie Sun , Xiaoyu Li , Lianhui Yu , Zhigang Wang , Geng Chen , Guowu Yang

We propose a novel exact algorithm for the transportation problem, one of the paradigmatic network optimization problems. The algorithm, denoted Iterated Inside Out, requires in input a basic feasible solution and is composed by two main…

Optimization and Control · Mathematics 2023-03-30 Roberto Bargetto , Federico Della Croce , Rosario Scatamacchia

Solving linear systems and quadratic programming (QP) problems are both ubiquitous tasks in the engineering and computing fields. Direct methods for solving systems, such as Cholesky, LU, and QR factorizations, exhibit data-independent time…

Optimization and Control · Mathematics 2025-07-08 Liang Wu , Richard D. Braatz

We describe a general method to obtain quantum speedups of classical algorithms which are based on the technique of backtracking, a standard approach for solving constraint satisfaction problems (CSPs). Backtracking algorithms explore a…

Quantum Physics · Physics 2016-01-05 Ashley Montanaro

We describe algorithms, and experimental strategies, for the Pareto optimal control problem of simultaneously driving an arbitrary number of quantum observable expectation values to their respective extrema. Conventional quantum optimal…

Quantum Physics · Physics 2009-11-13 Raj Chakrabarti , Rebing Wu , Herschel Rabitz

We study quantum interior point methods (QIPMs) for second-order cone programming (SOCP), guided by the example use case of portfolio optimization (PO). We provide a complete quantum circuit-level description of the algorithm from problem…

We introduce a novel hybrid quantum-classical variational optimization method for unconstrained binary combinatorial optimization problems on gate-model quantum computers, integrating a custom variational ansatz, staged feedback-based dual…

Quantum optimization has emerged as a promising frontier of quantum computing, providing novel numerical approaches to mathematical optimization problems. The main goal of this paper is to facilitate interdisciplinary research between the…

Optimization and Control · Mathematics 2025-09-05 Alexey Bochkarev , Raoul Heese , Sven Jäger , Philine Schiewe , Anita Schöbel

We propose an inexact infeasible arc-search interior-point method for solving linear optimization problems. The method combines an arc-search strategy with inexact solutions to Newton systems and admits a polynomial iteration complexity…

Optimization and Control · Mathematics 2026-01-08 Einosuke Iida , Makoto Yamashita

The growing demand for solving large-scale, data-intensive linear and conic optimization problems, particularly in applications such as artificial intelligence and machine learning, has highlighted the limitations of classical interior…

Classical optimization algorithms in machine learning often take a long time to compute when applied to a multi-dimensional problem and require a huge amount of CPU and GPU resource. Quantum parallelism has a potential to speed up machine…

Quantum Physics · Physics 2019-11-21 Venkat R. Dasari , Mee Seong Im , Lubjana Beshaj

A quantum computer consists of a set of quantum bits upon which operations called gates are applied to perform computations. In order to perform quantum algorithms, physicists would like to design arbitrary gates to apply to quantum bits.…

Quantum Physics · Physics 2012-06-18 Jeffrey Booth