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DNA methylation is an epigenetic mechanism that regulates gene expression by adding methyl groups to DNA. Abnormal methylation patterns can disrupt gene expression and have been linked to cancer development. To quantify DNA methylation,…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Manahil Raza , Muhammad Dawood , Talha Qaiser , Nasir M. Rajpoot

Unsupervised domain adaptation (UDA) is vital for alleviating the workload of labeling 3D point cloud data and mitigating the absence of labels when facing a newly defined domain. Various methods of utilizing images to enhance the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Jingyi Xu , Weidong Yang , Lingdong Kong , Youquan Liu , Rui Zhang , Qingyuan Zhou , Ben Fei

In this paper we develop a novel Topological Data Analysis (TDA) approach for studying graph representations of time series of dynamical systems. Specifically, we show how persistent homology, a tool from TDA, can be used to yield a…

Chaotic Dynamics · Physics 2020-01-28 Audun Myers , Elizabeth Munch , Firas A. Khasawneh

A commonly recurring problem in structural protein studies, is the determination of all heavy atom positions from the knowledge of the central alpha-carbon coordinates. We employ advances in virtual reality to address the problem. The…

Biomolecules · Quantitative Biology 2014-12-30 Xubiao Peng , Alireza Chenani , Shuangwei Hu , Yifan Zhou , Antti J. Niemi

This paper proposes a method to visualize the discrimination power of intermediate-layer visual patterns encoded by a DNN. Specifically, we visualize (1) how the DNN gradually learns regional visual patterns in each intermediate layer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-08 Mingjie Li , Shaobo Wang , Quanshi Zhang

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Network visualisation techniques are important tools for the exploratory analysis of complex systems. While these methods are regularly applied to visualise data on complex networks, we increasingly have access to time series data that can…

Social and Information Networks · Computer Science 2020-08-26 Vincenzo Perri , Ingo Scholtes

Software libraries for Topological Data Analysis (TDA) offer limited support for interactive visualization. Most libraries only allow to visualize topological descriptors (e.g., persistence diagrams), and lose the connection with the…

Graphics · Computer Science 2022-04-22 Xueyi Bao , Guoxi Liu , Federico Iuricich

Cell-level dense prediction is central to computational pathology, but remains challenging due to fine-grained histological structures, strong domain shifts, and costly dense annotations. Existing ViT-based pathology foundation models rely…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Weiming Chen , Xitong Ling , Zhenyang Cai , Xidong Wang , Jiawen Li , Tian Guan , Benyou Wang , Yonghong He

Leveraging hypergraph structures to model advanced processes has gained much attention over the last few years in many areas, ranging from protein-interaction in computational biology to image retrieval using machine learning. Hypergraph…

Human-Computer Interaction · Computer Science 2021-12-07 Maximilian T. Fischer , Alexander Frings , Daniel A. Keim , Daniel Seebacher

Multi-modal retrieval becomes increasingly popular in practice. However, the existing retrievers are mostly text-oriented, which lack the capability to process visual information. Despite the presence of vision-language models like CLIP,…

Information Retrieval · Computer Science 2024-06-07 Junjie Zhou , Zheng Liu , Shitao Xiao , Bo Zhao , Yongping Xiong

Stochastic models are often used to help understand the behavior of intracellular biochemical processes. The most common such models are continuous time Markov chains (CTMCs). Parametric sensitivities, which are derivatives of expectations…

Numerical Analysis · Mathematics 2014-11-19 Elizabeth Skubak Wolf , David F. Anderson

Analyzing nonadiabatic molecular dynamics trajectories traditionally heavily relies on expert intuition and visual pattern recognition, a process that is difficult to formalize. We present VisU, a vision-driven framework that leverages the…

Chemical Physics · Physics 2026-01-06 Yifei Zhu , Jiahui Zhang , Binni Huang , Zhenggang Lan

The central dogma of molecular biology is the principal framework for understanding how nucleic acid information is propagated and used by living systems to create complex biomolecules. Here, by integrating the structural and dynamic…

Biological Physics · Physics 2018-10-04 Jihoon Shin , Junghoon Kim , Sung Ha Park , Tai Hwan Ha

Deep learning has revolutionized the early detection of breast cancer, resulting in a significant decrease in mortality rates. However, difficulties in obtaining annotations and huge variations in distribution between training sets and real…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Yuxiang Yang , Xinyi Zeng , Pinxian Zeng , Binyu Yan , Xi Wu , Jiliu Zhou , Yan Wang

Answering semantically-complicated questions according to an image is challenging in Visual Question Answering (VQA) task. Although the image can be well represented by deep learning, the question is always simply embedded and cannot well…

Computer Vision and Pattern Recognition · Computer Science 2021-12-15 JianJian Cao , Xiameng Qin , Sanyuan Zhao , Jianbing Shen

Domain shift presents a significant challenge in applying Deep Learning to the segmentation of 3D medical images from sources like Magnetic Resonance Imaging (MRI) and Computed Tomography (CT). Although numerous Domain Adaptation methods…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Boris Shirokikh , Anvar Kurmukov , Mariia Donskova , Valentin Samokhin , Mikhail Belyaev , Ivan Oseledets

2D display is a fast and economical way of visualizing polymorphism and comparing genomes, which is based on the separation of DNA fragments in two steps, according first to their size and then to their sequence composition. In this paper,…

Biomolecules · Quantitative Biology 2009-10-29 Ana-Maria Florescu , Marc Joyeux , Benedicte Lafay

A source model trained on source data and a target model learned through unsupervised domain adaptation (UDA) usually encode different knowledge. To understand the adaptation process, we portray their knowledge difference with image…

Computer Vision and Pattern Recognition · Computer Science 2021-05-05 Yunzhong Hou , Liang Zheng

Despite notable advancements, the integration of deep learning (DL) techniques into impactful clinical applications, particularly in the realm of digital histopathology, has been hindered by challenges associated with achieving robust…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Sebastian Doerrich , Francesco Di Salvo , Christian Ledig
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