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Temporal graph neural networks have shown promising results in learning inductive representations by automatically extracting temporal patterns. However, previous works often rely on complex memory modules or inefficient random walk methods…

Machine Learning · Computer Science 2024-01-10 Mohammad Ali Alomrani , Mahdi Biparva , Yingxue Zhang , Mark Coates

Analysis of large dynamic networks is a thriving research field, typically relying on 2D graph representations. The advent of affordable head mounted displays however, sparked new interest in the potential of 3D visualization for immersive…

Human-Computer Interaction · Computer Science 2020-09-11 Johannes Sorger , Manuela Waldner , Wolfgang Knecht , Alessio Arleo

Significant progress in computer hardware and software have enabled molecular dynamics (MD) simulations to model complex biological phenomena such as protein folding. However, enabling MD simulations to access biologically relevant…

Biomolecules · Quantitative Biology 2019-08-02 Heng Ma , Debsindhu Bhowmik , Hyungro Lee , Matteo Turilli , Michael T. Young , Shantenu Jha , Arvind Ramanathan

This paper focuses on representation learning for dynamic graphs with temporal interactions. A fundamental issue is that both the graph structure and the nodes own their own dynamics, and their blending induces intractable complexity in the…

Machine Learning · Computer Science 2025-10-02 Tiexin Qin , Benjamin Walker , Terry Lyons , Hong Yan , Haoliang Li

Often the analysis of time-dependent chemical and biophysical systems produces high-dimensional time-series data for which it can be difficult to interpret which individual features are most salient. While recent work from our group and…

This paper proposes a method to visualize the discrimination power of intermediate-layer visual patterns encoded by a DNN. Specifically, we visualize (1) how the DNN gradually learns regional visual patterns in each intermediate layer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-08 Mingjie Li , Shaobo Wang , Quanshi Zhang

Unsupervised graph-level anomaly detection (UGAD) has received remarkable performance in various critical disciplines, such as chemistry analysis and bioinformatics. Existing UGAD paradigms often adopt data augmentation techniques to…

Machine Learning · Computer Science 2024-05-07 Jindong Li , Qianli Xing , Qi Wang , Yi Chang

Performing full-resolution atomistic simulations of nucleic acid folding has remained a challenge for biomolecular modeling. Understanding how nucleic acids fold and how they transition between different folded structures as they unfold and…

Biomolecules · Quantitative Biology 2022-05-18 Chi H. Mak

Drug target binding affinity (DTA) is a key criterion for drug screening. Existing experimental methods are time-consuming and rely on limited structural and domain information. While learning-based methods can model sequence and structural…

Machine Learning · Computer Science 2024-06-26 Xi Xiao , Wentao Wang , Jiacheng Xie , Lijing Zhu , Gaofei Chen , Zhengji Li , Tianyang Wang , Min Xu

Dimensionality reduction is a common method for analyzing and visualizing high-dimensional data. However, reasoning dynamically about the results of a dimensionality reduction is difficult. Dimensionality-reduction algorithms use complex…

Human-Computer Interaction · Computer Science 2018-11-30 Marco Cavallo , Çağatay Demiralp

We present a Vlasov-DArwin numerical code (ViDA) specifically designed to address plasma physics problems, where small-scale high accuracy is requested even during the non linear regime to guarantee a clean description of the plasma…

Protein dynamics play a crucial role in many biological processes and drug interactions. However, measuring, and simulating protein dynamics is challenging and time-consuming. While machine learning holds promise in deciphering the…

Machine Learning · Computer Science 2024-08-23 Sina Sarparast , Aldo Zaimi , Maximilian Ebert , Michael-Rock Goldsmith

Graph embedding provides an efficient solution for graph analysis by converting the graph into a low-dimensional space which preserves the structure information. In contrast to the graph structure data, the i.i.d. node embedding can be…

Machine Learning · Computer Science 2017-05-16 Hongyun Cai , Vincent W. Zheng , Kevin Chen-Chuan Chang

A recent paper on visualizing the sensitivity of hadronic experiments to nucleon structure [1] introduces the tool PDFSense which defines measures to allow the user to judge the sensitivity of PDF fits to a given experiment. The sensitivity…

High Energy Physics - Phenomenology · Physics 2018-10-17 Dianne Cook , Ursula Laa , German Valencia

A witness drawing of a graph is a visualization that clearly shows a given property of a graph. We study and implement various drawing paradigms for witness drawings to clearly show that graphs have bounded pathwidth or treewidth. Our…

Computational Geometry · Computer Science 2025-08-28 Alvin Chiu , Thomas Depian , David Eppstein , Michael T. Goodrich , Martin Nöllenburg

Multivariate graphs are prolific across many fields, including transportation and neuroscience. A key task in graph analysis is the exploration of connectivity, to, for example, analyze how signals flow through neurons, or to explore how…

Network visualisation techniques are important tools for the exploratory analysis of complex systems. While these methods are regularly applied to visualise data on complex networks, we increasingly have access to time series data that can…

Social and Information Networks · Computer Science 2020-08-26 Vincenzo Perri , Ingo Scholtes

This article presents a novel visualization approach for dynamic graphs, the versinus method, specially useful for real world networks exhibiting free-scale properties. With a simple and fixed layout, and a small set of visual markups, the…

Social and Information Networks · Computer Science 2014-12-30 Renato Fabbri

Graphs are ubiquitous data structures for representing interactions between entities. With an emphasis on the use of graphs to represent chemical molecules, we explore the task of learning to generate graphs that conform to a distribution…

Machine Learning · Computer Science 2019-03-08 Qi Liu , Miltiadis Allamanis , Marc Brockschmidt , Alexander L. Gaunt

Single-molecule experiments provide new insights into biological processes hitherto not accessible by measurements performed on bulk systems. We report on a study of the kinetics of a triple-branch DNA molecule with four conformational…

Biological Physics · Physics 2011-06-13 Sandra Engel , Anna Alemany , Nuria Forns , Philipp Maass , Felix Ritort