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Modelling and predicting protein configurations is crucial for advancing drug discovery, enabling the design of treatments for life-threatening diseases. A critical aspect of this challenge is rotamer optimisation - the determination of…

Quantum Physics · Physics 2025-07-28 Anastasia Agathangelou , Dilhan Manawadu , Ivano Tavernelli

Atomic level qubits in silicon are attractive candidates for large-scale quantum computing, however, their quantum properties and controllability are sensitive to details such as the number of donor atoms comprising a qubit and their…

Mesoscale and Nanoscale Physics · Physics 2020-03-17 Muhammad Usman , Yi Z. Wong , Charles D. Hill , Lloyd C. L. Hollenberg

Quantum machine learning (QML) is promising for potential speedups and improvements in conventional machine learning (ML) tasks (e.g., classification/regression). The search for ideal QML models is an active research field. This includes…

Quantum Physics · Physics 2022-02-07 Mahabubul Alam , Swaroop Ghosh

In this paper, we propose a quantum computing oriented benchmark for combinatorial optimization. This benchmark, coined as QOPTLib, is composed of 40 instances equally distributed over four well-known problems: Traveling Salesman Problem,…

Quantum Physics · Physics 2024-04-25 Eneko Osaba , Esther Villar-Rodriguez

Recent work suggests that quantum machine learning techniques can be used for classical image classification by encoding the images in quantum states and using a quantum neural network for inference. However, such work has been restricted…

Quantum Physics · Physics 2021-10-13 Ali Mohsen , Mo Tiwari

ROM-based quantum computation (QC) is an alternative to oracle-based QC. It has the advantages of being less ``magical'', and being more suited to implementing space-efficient computation (i.e. computation using the minimum number of…

Quantum Physics · Physics 2009-11-07 D. R. Sypher , I. M. Brereton , H. M. Wiseman , B. L. Hollis , B. C. Travaglione

Quantum image processing is a research field that explores the use of quantum computing and algorithms for image processing tasks such as image encoding and edge detection. Although classical edge detection algorithms perform reasonably…

This paper aims to implement and evaluate the performance of quantum computing on solving combinatorial optimization problems arising from the operations of the power grid. To this end, we construct a novel mixed integer conic programming…

Systems and Control · Electrical Eng. & Systems 2022-08-17 Phuong Ngo , Christan Thomas , Hieu Nguyen , Abdullah Eroglu , Konstantinos Oikonomou

The experimental realization of quantum information systems will be difficult due to how sensitive quantum information is to noise. Overcoming this sensitivity is central to designing quantum networks capable of transmitting quantum…

Quantum Physics · Physics 2023-07-13 Matheus Guedes de Andrade , Jake Navas , Inès Montaño , Don Towsley

The rapid growth of computer vision and increasingly complex image recognition tasks has exposed fundamental computational limitations of classical machine learning models, motivating the exploration of quantum computing as an emerging new…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Sudip Vhaduri , Ryan Gammon , Sayanton Dibbo

Quantum computations are typically compiled into a circuit of basic quantum gates. Just like for classical circuits, a quantum compiler should optimize the quantum circuit, e.g. by minimizing the number of required gates. Optimizing quantum…

Quantum Physics · Physics 2023-03-31 Raban Iten , Romain Moyard , Tony Metger , David Sutter , Stefan Woerner

Many computational problems are unchanged under some symmetry operation. In classical machine learning, this can be reflected with the layer structure of the neural network. In quantum machine learning, the ansatz can be tuned to correspond…

One of the major benefits of quantum computing is the potential to resolve complex computational problems faster than can be done by classical methods. There are many prototype-based clustering methods in use today, and the selection of the…

Quantum Physics · Physics 2023-05-16 Nicholas R. Allgood , Ajinkya Borle , Charles K. Nicholas

Quantum Approximate Optimization Algorithms (QAOA) promise efficient solutions to classically intractable combinatorial optimization problems by harnessing shallow-depth quantum circuits. Yet, their performance and scalability often hinge…

Quantum Physics · Physics 2025-05-02 Kuan-Cheng Chen , Hiromichi Matsuyama , Wei-Hao Huang

In the oracle identification problem, we are given oracle access to an unknown N-bit string x promised to belong to a known set C of size M and our task is to identify x. We present a quantum algorithm for the problem that is optimal in its…

Quantum Physics · Physics 2014-04-24 Robin Kothari

This work presents a novel fundamental algorithm for for defining and training Neural Networks in Quantum Information based on time evolution and the Hamiltonian. Classical Neural Network algorithms (ANN) are computationally expensive. For…

Machine Learning · Computer Science 2020-03-24 Aditya Dendukuri , Blake Keeling , Arash Fereidouni , Joshua Burbridge , Khoa Luu , Hugh Churchill

Time series play a fundamental role in many domains, capturing a plethora of information about the underlying data-generating processes. When a process generates multiple synchronized signals we are faced with multidimensional time series.…

Data Structures and Algorithms · Computer Science 2026-03-20 Matteo Ceccarello , Francesco Pio Monaco , Francesco Silvestri

Quantum heuristics have shown promise in solving various optimization problems, including lattice protein folding. Equally relevant is the inverse problem, protein design, where one seeks sequences that fold to a given target structure. The…

This work shows that minimizing the depth of a quantum circuit composed of commuting operations reduces to a vertex coloring problem on an appropriately constructed graph, where gates correspond to vertices and edges encode…

Quantum Physics · Physics 2026-02-11 Hochang Lee , Kyung Chul Jeong , Panjin Kim

Magnetic resonance image reconstruction starting from undersampled k-space data requires the recovery of many potential nonlinear features, which is very difficult for algorithms to recover these features. In recent years, the development…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Shuo Zhou , Yihang Zhou , Congcong Liu , Yanjie Zhu , Hairong Zheng , Dong Liang , Haifeng Wang