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Brain network analysis based on functional Magnetic Resonance Imaging (fMRI) is pivotal for diagnosing brain disorders. Existing approaches typically rely on predefined functional sub-networks to construct sub-network associations. However,…
In clinical practice, human radiologists actually review medical images with high resolution monitors and zoom into region of interests (ROIs) for a close-up examination. Inspired by this observation, we propose a hierarchical graph neural…
The medical image is characterized by the inter-class indistinction, high variability, and noise, where the recognition of pixels is challenging. Unlike previous self-attention based methods that capture context information from one level,…
We consider the problem of abnormality localization for clinical applications. While deep learning has driven much recent progress in medical imaging, many clinical challenges are not fully addressed, limiting its broader usage. While…
The proliferation of high-dimensional datasets in fields such as genomics, healthcare, and finance has created an urgent need for machine learning models that are both highly accurate and inherently interpretable. While traditional deep…
The growing demand for head magnetic resonance imaging (MRI) examinations, along with a global shortage of radiologists, has led to an increase in the time taken to report head MRI scans around the world. For many neurological conditions,…
The detection of weak, spatially distributed anomalies in volumetric medical imaging remains challenging due to the difficulty of integrating subtle signals across non-adjacent regions. This study presents a controlled comparison of sixteen…
Graph-level anomaly detection aims to identify abnormal graphs that exhibit deviant structures and node attributes compared to the majority in a graph set. One primary challenge is to learn normal patterns manifested in both fine-grained…
Brain networks, graphical models such as those constructed from MRI, have been widely used in pathological prediction and analysis of brain functions. Within the complex brain system, differences in neuronal connection strengths parcellate…
Purpose: The goal of this work was to develop a deep network for whole-head segmentation including clinical MRIs with abnormal anatomy, and compile the first public benchmark dataset for this purpose. We collected 98 MRIs with volumetric…
Mining human-brain networks to discover patterns that can be used to discriminate between healthy individuals and patients affected by some neurological disorder, is a fundamental task in neuroscience. Learning simple and interpretable…
Brain networks has attracted the interests of many neuroscientists. From functional MRI (fMRI) data, statistical tools have been developed to recover brain networks. However, the dimensionality of whole-brain fMRI, usually in hundreds of…
Autism Spectrum Disorder (ASD) is a pervasive developmental disorder of the central nervous system, primarily manifesting in childhood. It is characterized by atypical and repetitive behaviors. Currently, diagnostic methods mainly rely on…
Leveraging knowledge from electronic health records (EHRs) to predict a patient's condition is essential to the effective delivery of appropriate care. Clinical notes of patient EHRs contain valuable information from healthcare…
When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…
The estimation of sparse hierarchical components reflecting patterns of the brain's functional connectivity from rsfMRI data can contribute to our understanding of the brain's functional organization, and can lead to biomarkers of diseases.…
The increasing digitization of medical imaging enables machine learning based improvements in detecting, visualizing and segmenting lesions, easing the workload for medical experts. However, supervised machine learning requires reliable…
The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…
Anomaly detection consists in identifying, within a dataset, those samples that significantly differ from the majority of the data, representing the normal class. It has many practical applications, e.g. ranging from defective product…
In this paper, we describe our method for classification of brain magnetic resonance (MR) images into different abnormalities and healthy classes based on the deep neural network. We propose our method to detect high and low-grade glioma,…