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Newly-introduced deep learning architectures, namely BERT, XLNet, RoBERTa and ALBERT, have been proved to be robust on several NLP tasks. However, the datasets trained on these architectures are fixed in terms of size and generalizability.…

Computation and Language · Computer Science 2020-09-29 Jean-Philippe Corbeil , Hadi Abdi Ghadivel

Gene transformer models such as Nucleotide Transformer, DNABert, and LOGO are trained to learn optimal gene sequence representations by using the Masked Language Modeling (MLM) training objective over the complete Human Reference Genome.…

Computation and Language · Computer Science 2024-10-23 Soumyadeep Roy , Shamik Sural , Niloy Ganguly

Pathology text mining is a challenging task given the reporting variability and constant new findings in cancer sub-type definitions. However, successful text mining of a large pathology database can play a critical role to advance 'big…

Computation and Language · Computer Science 2022-05-17 Thiago Santos , Amara Tariq , Susmita Das , Kavyasree Vayalpati , Geoffrey H. Smith , Hari Trivedi , Imon Banerjee

NeuroEvolution is one of the most competitive evolutionary learning frameworks for designing novel neural networks for use in specific tasks, such as logic circuit design and digital gaming. However, the application of benchmark methods…

Neural and Evolutionary Computing · Computer Science 2021-10-11 Haoling Zhang , Chao-Han Huck Yang , Hector Zenil , Narsis A. Kiani , Yue Shen , Jesper N. Tegner

DNA sequence alignment involves assigning short DNA reads to the most probable locations on an extensive reference genome. This process is crucial for various genomic analyses, including variant calling, transcriptomics, and epigenomics.…

We present a framework for discriminative sequence classification where the learner works directly in the high dimensional predictor space of all subsequences in the training set. This is possible by employing a new coordinate-descent…

Machine Learning · Computer Science 2010-08-04 Georgiana Ifrim , Carsten Wiuf

A coreset is a subset of the training set, using which a machine learning algorithm obtains performances similar to what it would deliver if trained over the whole original data. Coreset discovery is an active and open line of research as…

Machine Learning · Computer Science 2020-02-21 Pietro Barbiero , Giovanni Squillero , Alberto Tonda

Most real-world classification problems deal with imbalanced datasets, posing a challenge for Artificial Intelligence (AI), i.e., machine learning algorithms, because the minority class, which is of extreme interest, often proves difficult…

Machine Learning · Computer Science 2025-04-28 Gissel Velarde , Michael Weichert , Anuj Deshmunkh , Sanjay Deshmane , Anindya Sudhir , Khushboo Sharma , Vaibhav Joshi

Gene enhancers control when and where genes switch on, yet their sequence diversity and tissue specificity make them hard to pinpoint in colorectal cancer. We take a sequence-only route and fine-tune DNABERT-2, a transformer genomic…

Genomics · Quantitative Biology 2025-10-01 Darren King , Yaser Atlasi , Gholamreza Rafiee

As a pre-trained Transformer model, BERT (Bidirectional Encoder Representations from Transformers) has achieved ground-breaking performance on multiple NLP tasks. On the other hand, Boosting is a popular ensemble learning technique which…

Computation and Language · Computer Science 2020-09-15 Tongwen Huang , Qingyun She , Junlin Zhang

Applying machine learning to biological sequences - DNA, RNA and protein - has enormous potential to advance human health, environmental sustainability, and fundamental biological understanding. However, many existing machine learning…

Machine Learning · Statistics 2023-04-11 Alan Nawzad Amin , Eli Nathan Weinstein , Debora Susan Marks

Encoder-only languages models are frequently used for a variety of standard machine learning tasks, including classification and retrieval. However, there has been a lack of recent research for encoder models, especially with respect to…

Computation and Language · Computer Science 2025-09-09 Marc Marone , Orion Weller , William Fleshman , Eugene Yang , Dawn Lawrie , Benjamin Van Durme

Efficient text classification is essential for handling the increasing volume of academic publications. This study explores the use of pre-trained language models (PLMs), including BERT, SciBERT, BioBERT, and BlueBERT, fine-tuned on the Web…

Computation and Language · Computer Science 2025-09-09 Zhyar Rzgar K Rostam , Gábor Kertész

Significant advances have been made in recent years on Natural Language Processing with machines surpassing human performance in many tasks, including but not limited to Question Answering. The majority of deep learning methods for Question…

Machine Learning · Computer Science 2024-09-05 Ayush Jain , N. M. Meenachi , B. Venkatraman

We consider the task of discovering gene regulatory networks, which are defined as sets of genes and the corresponding transcription factors which regulate their expression levels. This can be viewed as a variable selection problem,…

Methodology · Statistics 2014-12-04 Justin Bleich , Adam Kapelner , Edward I. George , Shane T. Jensen

This paper demonstrates the utility of organized numerical representations of genes in research involving flat string gene formats (i.e., FASTA/FASTQ5). FASTA/FASTQ files have several current limitations, such as their large file sizes,…

Genomics · Quantitative Biology 2023-08-11 Daniel H. Um , David A. Knowles , Gail E. Kaiser

Manual labeling of animal images remains a significant bottleneck in ecological research, limiting the scale and efficiency of biodiversity monitoring efforts. This study investigates whether state-of-the-art Vision Transformer (ViT)…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Hugo Markoff , Stefan Hein Bengtson , Michael Ørsted

Image classification is a fundamental task in computer vision, and the quest to enhance DNN accuracy without inflating model size or latency remains a pressing concern. We make a couple of advances in this regard, leading to a novel…

Computer Vision and Pattern Recognition · Computer Science 2024-04-23 Hasanul Mahmud , Kevin Desai , Palden Lama , Sushil K. Prasad

In DNA computing, it is impossible to decide whether a specific hybridization among complex DNA molecules is effective or not within acceptable time. In order to address this common problem, we introduce a new method based on the machine…

Quantitative Methods · Quantitative Biology 2018-07-03 Weijun Zhu

Transformer-based masked language models such as BERT, trained on general corpora, have shown impressive performance on downstream tasks. It has also been demonstrated that the downstream task performance of such models can be improved by…

Computation and Language · Computer Science 2023-05-04 Zhi Hong , Aswathy Ajith , Gregory Pauloski , Eamon Duede , Kyle Chard , Ian Foster