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DNA language models have advanced genomics, but their downstream performance varies widely due to differences in tokenization, pretraining data, and architecture. We argue that a major bottleneck lies in tokenizing sparse and unevenly…

Genomics · Quantitative Biology 2025-12-23 Xiaoxiao Zhou , Zihan Wang , Jingbo Shang , Yang E. Li

DNA sequences encode critical genetic information, yet their variable length and discrete nature impede direct utilization in deep learning models. Existing DNA representation schemes convert sequences into numerical vectors but fail to…

Genomics · Quantitative Biology 2025-12-16 Zhiyuan Peng , Naifan Zhang , Yuanbo Tang , Yang Li

We explore a framework for protein sequence representation learning that decomposes the task between manifold learning and distributional modelling. Specifically we present a Latent Space Diffusion architecture which combines a protein…

Machine Learning · Computer Science 2025-03-25 Eoin Quinn , Ghassene Jebali , Maxime Seince , Oliver Bent

This paper proposes a novel Attention-based Encoder-Decoder network for End-to-End Neural speaker Diarization (AED-EEND). In AED-EEND system, we incorporate the target speaker enrollment information used in target speaker voice activity…

Sound · Computer Science 2023-08-16 Zhengyang Chen , Bing Han , Shuai Wang , Yanmin Qian

Recently Transformer and Convolution neural network (CNN) based models have shown promising results in EEG signal processing. Transformer models can capture the global dependencies in EEG signals through a self-attention mechanism, while…

Signal Processing · Electrical Eng. & Systems 2023-09-11 Chenyu Liu , Xinliang Zhou , Yang Liu

Sequencing a genome to determine an individual's DNA produces an enormous number of short nucleotide subsequences known as reads, which must be reassembled to reconstruct the full genome. We present a method for analyzing this type of data…

Machine Learning · Computer Science 2025-05-23 Filip Thor , Carl Nettelblad

Automated detection of software vulnerabilities is critical for enhancing security, yet existing methods often struggle with the complexity and diversity of modern codebases. In this paper, we introduce EnStack, a novel ensemble stacking…

Software Engineering · Computer Science 2024-11-26 Shahriyar Zaman Ridoy , Md. Shazzad Hossain Shaon , Alfredo Cuzzocrea , Mst Shapna Akter

Masked language modeling has become a standard pretraining objective for training encoder-based language models. In this approach, certain tokens in the input are masked, and the model learns to predict them using the surrounding context.…

Artificial Intelligence · Computer Science 2026-05-28 Gokul Srinivasagan , Kai Hartung , Munir Georges

Specialised transformers-based models (such as BioBERT and BioMegatron) are adapted for the biomedical domain based on publicly available biomedical corpora. As such, they have the potential to encode large-scale biological knowledge. We…

Computation and Language · Computer Science 2022-12-22 Oskar Wysocki , Zili Zhou , Paul O'Regan , Deborah Ferreira , Magdalena Wysocka , Dónal Landers , André Freitas

Text images contain both visual and linguistic information. However, existing pre-training techniques for text recognition mainly focus on either visual representation learning or linguistic knowledge learning. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Pengyuan Lyu , Chengquan Zhang , Shanshan Liu , Meina Qiao , Yangliu Xu , Liang Wu , Kun Yao , Junyu Han , Errui Ding , Jingdong Wang

Transformer architectures achieve state-of-the-art performance across a wide range of pattern recognition and natural language processing tasks, but their scaling is accompanied by substantial parameter growth and redundancy in the…

Computation and Language · Computer Science 2026-03-09 Alaa El Ichi , Khalide Jbilou , Mohamed El Guide , Franck Dufrenois

The accurate interpretation of Electrocardiogram (ECG) signals is pivotal for diagnosing cardiovascular diseases. Integrating ECG signals with accompanying textual reports further holds immense potential to enhance clinical diagnostics by…

Machine Learning · Computer Science 2025-05-08 Hung Manh Pham , Aaqib Saeed , Dong Ma

In this paper, we propose a new deep learning network "GENet", it combines the multi-layer network architec- ture and graph embedding framework. Firstly, we use simplest unsupervised learning PCA/LDA as first layer to generate the low-…

Computer Vision and Pattern Recognition · Computer Science 2014-09-26 Yufei Gan , Teng Yang , Chu He

In recent years, many interpretability methods have been proposed to help interpret the internal states of Transformer-models, at different levels of precision and complexity. Here, to analyze encoder-decoder Transformers, we propose a…

Computation and Language · Computer Science 2024-04-04 Anna Langedijk , Hosein Mohebbi , Gabriele Sarti , Willem Zuidema , Jaap Jumelet

In communication and storage systems, error correction codes (ECCs) are pivotal in ensuring data reliability. As deep learning's applicability has broadened across diverse domains, there is a growing research focus on neural network-based…

Machine Learning · Computer Science 2023-08-28 Seong-Joon Park , Hee-Youl Kwak , Sang-Hyo Kim , Sunghwan Kim , Yongjune Kim , Jong-Seon No

Large language models (LLMs) achieve remarkable generative performance, yet their output quality is dependent on the decoding strategy. While sampling-based methods (e.g., top-k, nucleus) and search-and-select based methods (e.g., beam…

Machine Learning · Computer Science 2026-05-12 Benjamin Patrick Evans , Sumitra Ganesh , Leo Ardon

Learning sentence embeddings often requires a large amount of labeled data. However, for most tasks and domains, labeled data is seldom available and creating it is expensive. In this work, we present a new state-of-the-art unsupervised…

Computation and Language · Computer Science 2021-09-13 Kexin Wang , Nils Reimers , Iryna Gurevych

Learning token embeddings based on token co-occurrence statistics has proven effective for both pre-training and fine-tuning in natural language processing. However, recent studies have pointed out that the distribution of learned…

Computation and Language · Computer Science 2024-10-17 Ying Zhang , Dongyuan Li , Manabu Okumura

This study demonstrates that generative large language models can be utilized in a more flexible manner for DNA sequence analysis and classification tasks compared to traditional transformer encoder-based models. While recent encoder-based…

Computation and Language · Computer Science 2025-03-07 Hyunwoo Yoo

We frame embedding inversion as conditional masked diffusion, recovering all tokens in parallel through iterative denoising rather than sequential autoregressive generation. A masked diffusion language model is conditioned on the target…

Computation and Language · Computer Science 2026-02-19 Han Xiao