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Recent progress on salient object detection mainly aims at exploiting how to effectively integrate multi-scale convolutional features in convolutional neural networks (CNNs). Many popular methods impose deep supervision to perform…

Computer Vision and Pattern Recognition · Computer Science 2021-01-21 Yun Liu , Ming-Ming Cheng , Xinyu Zhang , Guang-Yu Nie , Meng Wang

We introduce a model of DNA sequence evolution which can account for biases in mutation rates that depend on the identity of the neighboring bases. An analytic solution for this class of non-equilibrium models is developed by adopting…

Biological Physics · Physics 2007-05-23 Peter F. Arndt , Christopher B. Burge , Terence Hwa

The typical process for classifying and submitting a newly sequenced virus to the NCBI database involves two steps. First, a BLAST search is performed to determine likely family candidates. That is followed by checking the candidate…

Genomics · Quantitative Biology 2016-03-22 Troy Hernandez , Jie Yang

Cheap high-throughput DNA sequencing may soon become routine not only for human genomes but also for practically anything requiring the identification of living organisms from their DNA: tracking of infectious agents, control of food…

Genomics · Quantitative Biology 2014-03-05 Laurent Gautier , Ole Lund

DNA data storage systems encode digital data into DNA strands, enabling dense and durable storage. Efficient data retrieval depends on coverage depth, a key performance metric. We study the random access coverage depth problem and focus on…

Information Theory · Computer Science 2025-07-29 Şeyma Bodur , Stefano Lia , Hiram H. López , Rati Ludhani , Alberto Ravagnani , Lisa Seccia

Predicting protein secondary structure is a fundamental problem in protein structure prediction. Here we present a new supervised generative stochastic network (GSN) based method to predict local secondary structure with deep hierarchical…

Quantitative Methods · Quantitative Biology 2014-03-07 Jian Zhou , Olga G. Troyanskaya

Recent years have witnessed Spiking Neural Networks (SNNs) gaining attention for their ultra-low energy consumption and high biological plausibility compared with traditional Artificial Neural Networks (ANNs). Despite their distinguished…

Neural and Evolutionary Computing · Computer Science 2024-08-30 Jiahang Cao , Hanzhong Guo , Ziqing Wang , Deming Zhou , Hao Cheng , Qiang Zhang , Renjing Xu

String barcoding is a recently introduced technique for genomic-based identification of microorganisms. In this paper we describe the engineering of highly scalable algorithms for robust string barcoding. Our methods enable distinguisher…

Data Structures and Algorithms · Computer Science 2016-08-31 Bhaskar DasGupta , Kishori M. Konwar , Ion I. Mandoiu , Alex A. Shvartsman

A method for encoding information in DNA sequences is described. The method is based on the precision-resolution framework, and is aimed to work in conjunction with a recently suggested terminator-free template independent DNA synthesis…

Information Theory · Computer Science 2020-05-14 Siddharth Jain , Farzad Farnoud , Moshe Schwartz , Jehoshua Bruck

Despite recent improvements in computer vision, artificial visual systems' design is still daunting since an explanation of visual computing algorithms remains elusive. Salient object detection is one problem that is still open due to the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Gustavo Olague , Jose Armando Menendez-Clavijo , Matthieu Olague , Arturo Ocampo , Gerardo Ibarra-Vazquez , Rocio Ochoa , Roberto Pineda

Generating graph-structured data requires learning the underlying distribution of graphs. Yet, this is a challenging problem, and the previous graph generative methods either fail to capture the permutation-invariance property of graphs or…

Machine Learning · Computer Science 2022-06-16 Jaehyeong Jo , Seul Lee , Sung Ju Hwang

Recently, Deep Convolutional Neural Network (DCNN) has achieved tremendous success in many machine learning applications. Nevertheless, the deep structure has brought significant increases in computation complexity. Largescale deep learning…

Neural and Evolutionary Computing · Computer Science 2018-05-14 Zhe Li , Ji Li , Ao Ren , Caiwen Ding , Jeffrey Draper , Qinru Qiu , Bo Yuan , Yanzhi Wang

Because of DNA appealing features as perfect material, including minuscule size, defined structural repeat and rigidity, programmable DNA-mediated processing is a promising computing paradigm, which employs DNAs as information storing and…

Biological Physics · Physics 2015-08-17 Jian-Jun Shu , Qi-Wen Wang , Kian-Yan Yong , Fangwei Shao , Kee Jin Lee

Applying deep neural networks (DNNs) in mobile and safety-critical systems, such as autonomous vehicles, demands a reliable and efficient execution on hardware. Optimized dedicated hardware accelerators are being developed to achieve this.…

Machine Learning · Computer Science 2019-10-01 Christoph Schorn , Thomas Elsken , Sebastian Vogel , Armin Runge , Andre Guntoro , Gerd Ascheid

Distributed computing which uses Web services as fundamental elements, enables high-speed development of software applications through composing many interoperating, distributed, re-usable, and autonomous services. As a fundamental…

Artificial Intelligence · Computer Science 2019-01-18 Soheila Sadeghiram , Hui MA , Gang Chen

In this paper, we present a fully-dynamic distributed algorithm for maintaining a minimum spanning tree on general graphs with positive real edge weights. The goal of a dynamic MST algorithm is to update efficiently the minimum spanning…

Distributed, Parallel, and Cluster Computing · Computer Science 2007-05-23 Pradosh Kumar Mohapatra

With the rapid global spread of COVID-19, more and more data related to this virus is becoming available, including genomic sequence data. The total number of genomic sequences that are publicly available on platforms such as GISAID is…

Genomics · Quantitative Biology 2021-11-16 Sarwan Ali , Murray Patterson

Nucleic acid sequence design via codon optimization is a fundamental task with applications across synthetic biology, mRNA therapeutics, and vaccine design. Given a target protein, it is a major open challenge to navigate the…

Quantitative Methods · Quantitative Biology 2026-04-22 Mark Fornace , Christina Wuyan Wang , Michael Lindsey

Graph Convolutional Networks (GCNs) have been proved successful in the field of semi-supervised node classification by extracting structural information from graph data. However, the random selection of labeled nodes used by GCNs may lead…

Machine Learning · Computer Science 2023-01-12 Yao Xiao , Ji Xu , Jing Yang , Shaobo Li

We develop VSD, a method for conditioning a generative model of discrete, combinatorial designs on a rare desired class by efficiently evaluating a black-box (e.g. experiment, simulation) in a batch sequential manner. We call this task…

Machine Learning · Statistics 2025-11-24 Daniel M. Steinberg , Rafael Oliveira , Cheng Soon Ong , Edwin V. Bonilla
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