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Hyperparameter tuning is a critical yet computationally expensive step in training neural networks, particularly when the search space is high dimensional and nonconvex. Metaheuristic optimization algorithms are often used for this purpose…

Neural and Evolutionary Computing · Computer Science 2026-01-22 Amaras Nazarians , Sachin Kumar

Understanding the performance of machine learning models across diverse data distributions is critically important for reliable applications. Motivated by this, there is a growing focus on curating benchmark datasets that capture…

Machine Learning · Computer Science 2022-02-15 Weixin Liang , James Zou

Image segmentation is critical for applications such as medical imaging, augmented reality, and video surveillance. However, segmentation models often lack robustness, making them vulnerable to adversarial perturbations from subtle image…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Seif Mzoughi , Mohamed Elshafeia , Foutse Khomh

With widespread applications of artificial intelligence (AI), the capabilities of the perception, understanding, decision-making and control for autonomous systems have improved significantly in the past years. When autonomous systems…

Machine Learning · Computer Science 2020-05-26 Chongzhen Zhang , Jianrui Wang , Gary G. Yen , Chaoqiang Zhao , Qiyu Sun , Yang Tang , Feng Qian , Jürgen Kurths

Pairwise sequence alignment is one of the most computationally intensive kernels in genomic data analysis, accounting for more than 90% of the runtime for key bioinformatics applications. This method is particularly expensive for…

A major impediment to successful drug development is the complexity, cost, and scale of clinical trials. The detailed internal structure of clinical trial data can make conventional optimization difficult to achieve. Recent advances in…

The large volumes of sequencing data required to sample complex environments deeply pose new challenges to sequence analysis approaches. De novo metagenomic assembly effectively reduces the total amount of data to be analyzed but requires…

Over the past few years, the rapid development of deep learning technologies for computer vision has significantly improved the performance of medical image segmentation (MedISeg). However, the diverse implementation strategies of various…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Dong Zhang , Yi Lin , Hao Chen , Zhuotao Tian , Xin Yang , Jinhui Tang , Kwang Ting Cheng

Modern high throughput sequencing technologies like metagenomic sequencing generate millions of sequences which have to be classified based on their taxonomic rank. Modern approaches either apply local alignment and comparison to existing…

Genomics · Quantitative Biology 2023-03-14 Wolfgang Fuhl , Susanne Zabel , Kay Nieselt

Meta-learning is a general approach to equip machine learning models with the ability to handle few-shot scenarios when dealing with many tasks. Most existing meta-learning methods work based on the assumption that all tasks are of equal…

Machine Learning · Computer Science 2024-10-25 Zhaofeng Si , Shu Hu , Kaiyi Ji , Siwei Lyu

Life science is entering a new era of petabyte-level sequencing data. Converting such big data to biological insights represents a huge challenge for computational analysis. To this end, we developed DeepMetabolism, a biology-guided deep…

Genomics · Quantitative Biology 2017-05-10 Weihua Guo , You Xu , Xueyang Feng

In many personalized recommendation scenarios, the generalization ability of a target task can be improved via learning with additional auxiliary tasks alongside this target task on a multi-task network. However, this method often suffers…

Machine Learning · Computer Science 2022-03-15 Yun He , Xue Feng , Cheng Cheng , Geng Ji , Yunsong Guo , James Caverlee

The marine environment is one of the most important sources for microbial biodiversity on the planet. These microbes are drivers for many biogeochemical processes, and their enormous genetic potential is still not fully explored or…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-04-15 Espen Mikal Robertsen , Tim Kahlke , Inge Alexander Raknes , Edvard Pedersen , Erik Kjærner Semb , Martin Ernstsen , Lars Ailo Bongo , Nils Peder Willassen

Ternary Neural Networks (TNNs) have received much attention due to being potentially orders of magnitude faster in inference, as well as more power efficient, than full-precision counterparts. However, 2 bits are required to encode the…

Machine Learning · Computer Science 2021-07-30 Peng Chen , Bohan Zhuang , Chunhua Shen

The first step toward Seed Phenotyping i.e. the comprehensive assessment of complex seed traits such as growth, development, tolerance, resistance, ecology, yield, and the measurement of pa-rameters that form more complex traits is the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Venkat Margapuri , Mitchell Neilsen

Gradient based meta-learning methods are prone to overfit on the meta-training set, and this behaviour is more prominent with large and complex networks. Moreover, large networks restrict the application of meta-learning models on low-power…

Machine Learning · Computer Science 2022-06-06 Arnav Chavan , Rishabh Tiwari , Udbhav Bamba , Deepak K. Gupta

Optimization is key to solve many problems in computational biology. Global optimization methods provide a robust methodology, and metaheuristics in particular have proven to be the most efficient methods for many applications. Despite…

Optimization and Control · Mathematics 2013-11-25 Jose A Egea , David Henriques , Thomas Cokelaer , Alejandro F Villaverde , Julio R Banga , Julio Saez-Rodriguez

The accurate screening of candidate drug ligands against target proteins through computational approaches is of prime interest to drug development efforts. Such virtual screening depends in part on methods to predict the binding affinity…

Machine Learning · Computer Science 2024-10-22 Ho-Joon Lee , Prashant S. Emani , Mark B. Gerstein

Fine-grained visual classification aims to recognize objects belonging to many subordinate categories of a supercategory, where appearance alone often fails to distinguish highly similar classes. We propose a unified framework that…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Sumit Mamtani , Yash Thesia

Heterogeneity is a hallmark of complex diseases. Regression-based heterogeneity analysis, which is directly concerned with outcome-feature relationships, has led to a deeper understanding of disease biology. Such an analysis identifies the…

Methodology · Statistics 2022-11-29 Ziye Luo , Xinyue Yao , Yifan Sun , Xinyan Fan